二(4-硝基-2-(3,6,9-三氧杂癸基氧羰基)苯基)草酸酯 | 103638-91-1

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 中文名称: 二(4-硝基-2-(3,6,9-三氧杂癸基氧羰基)苯基)草酸酯
• 英文名称: Bis(4-nitro-2-(3,6,9-trioxadecyloxycarbonyl)phenyl)oxalate
• 英文别名: bis[2-[2-[2-(2-methoxyethoxy)ethoxy]ethoxycarbonyl]-4-nitrophenyl] oxalate
• CAS: 103638-91-1
• 化学式: C30H36N2O18
• 分子量: 712.6
• InChiKey: XDJYPHQPTUDHFO-UHFFFAOYSA-N

物化性质

• 熔点：
  65～69℃

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  50
• 可旋转键数：
  27
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  252
• 氢给体数：
  0
• 氢受体数：
  18

文献信息

• Colorimetric assay for the determination of density or activity of viable cells
  申请人：KING BREWERY CO., Ltd.

  公开号：EP0566109A1

  公开（公告）日：1993-10-20

  A convenient and rapid assay for activity and density of living cells in many samples is provided. That is, a oxidized type quinone such as 1,4-naphthoquinone, 2-methyl-1,4-naphthoquinone or tetramethyl-p-benzoquinone is reacted with a system to be determined. The Hydrogen peroxide thus produced is indirectly reacted with the colorimetric reagent by using enzyme or directly with the colorimetric reagent, the intensity of the color development thus caused is determined with a spectro phtometer(a colorimeter). A proper enzyme of the acceptor of hydrogen peroxide is peroxidase, indirect color reagent is sodium salt of N-(carboxymethylaminocarbonyl)-4,4'-bis(dimethylamino)-diphenylamine or leucocrystal violet are suitable for indirect colometric reagent, and direct colorimetric reagent is cytochrome c peroxidase.

  本发明提供了一种方便快捷的检测方法，用于检测许多样品中活细胞的活性和密度。即氧化型醌，如 1,4-萘醌、2-甲基-1,4-萘醌或四甲基对苯醌与待测定的系统反应。由此产生的过氧化氢通过酶与比色试剂间接反应，或直接与比色试剂反应，由此产生的显色强度用分光光度计（比色计）测定。适当的过氧化氢受体酶是过氧化物酶，间接比色试剂是 N-（羧甲基氨基羰基）-4,4'-双（二甲基氨基）-二苯胺钠盐或亮晶紫，它们都适用于间接比色试剂，直接比色试剂是细胞色素 c 过氧化物酶。
• [EN] LUMINESCENCE<br/>[FR] LUMINESCENCE
  申请人：UCL BUSINESS PLC

  公开号：WO2009056782A1

  公开（公告）日：2009-05-07

  The present invention provides an assay method comprising the steps of: (a)contacting a phthalimide with a developing agent to produce a chemiluminescent molecule or a chemiluminescent substrate; and (b)producing the chemiluminescent molecule or chemiluminescent substrate. The assay method can be, for example, a method of detecting a target or detecting migration of a phthalimide from a first location to a second location. The phthalimide is preferably 3-aminophthalimide or 5-aminophthalimide and the phthalimide is suitably a component of a complex comprising the phthalimide and a molecule such as a peptide, oligopeptide, polypeptide or antibody. The molecule to which the phthalimide is linked can be a target binding agent having a binding affinity for a target or be a cellular probe. Detection of a target may also include determining the amount of target as an assay result. The amount of chemiluminescence may be indicative of the amount of target.
• [EN] METHOD OF DETECTING VIRUS HAVING HEMAGGLUTININ-ESTERASE ACTIVITY<br/>[FR] MÉTHODE DE DÉTECTION DE VIRUS PRÉSENTANT UNE ACTIVITÉ D'HÉMAGGLUTININE-ESTÉRASE
  申请人：LEE JI HOON

  公开号：WO2021188568A1

  公开（公告）日：2021-09-23

  A method of detecting a virus having a hemagglutinin-esterase activity in a sample is disclosed, the method includes: contacting the sample with a substrate for an enzyme of hemagglutinin-esterase (HE) of coronavirus or hemagglutinin-esterase fusion protein (HEF) of influenza C virus; and detecting activity of the enzyme, the detection of the activity indicates that the sample contains coronavirus or influenza C virus.