2-aminomethylpyrimidine acetic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2-aminomethylpyrimidine acetic acid
• 英文别名: 2-{[(Pyrimidin-2-yl)methyl]amino}acetic acid；2-(pyrimidin-2-ylmethylamino)acetic acid
• 化学式: C₇H₉N₃O₂
• 分子量: 167.167
• InChiKey: IHBUDBAUOLDQOD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -3.1
• 重原子数：
  12
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  75.1
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  S)-4-(3-氯-4-甲氧基苯氨基)-5-羧基-2-(2-羟甲基-1-吡咯基)嘧啶 、 2-aminomethylpyrimidine acetic acid 在 1-羟基苯并三唑 、 盐酸-N-乙基-Nˊ-(3-二甲氨基丙基)碳二亚胺 、 三乙胺 作用下， 以 N,N-二甲基甲酰胺 、 甲醇 为溶剂， 反应 10.08h， 以68 g的产率得到阿伐那非
  参考文献：
  名称：

  [EN] POLYMORPHS OF AVANAFIL
  [FR] POLYMORPHES D'AVANAFIL

  摘要：

  公开号：

  WO2014174529A3

文献信息

• NEAR INFRARED RAY ABSORBENT COMPOSITION, NEAR INFRARED RAY CUT FILTER, SOLID IMAGE PICKUP ELEMENT, AND CAMERA MODULE
  申请人：FUJIFILM Corporation

  公开号：US20170227690A1

  公开（公告）日：2017-08-10

  Provided are a near infrared ray absorbent composition which can form a cured film having excellent near infrared ray shielding properties, a near infrared ray cut filter, a manufacturing method of a near infrared ray cut filter, a solid image pickup element, and a camera module. The near infrared ray absorbent composition includes a copper complex that is other than a copper phthalocyanine complex and has a maximum absorption wavelength in a wavelength range of 700 to 1,200 nm and in which a molar light absorption coefficient at the maximum absorption wavelength is greater than or equal to 100 (L/mol·cm).
• NEAR INFRARED ABSORBING COMPOSITION, NEAR INFRARED CUT FILTER, METHOD OF MANUFACTURING NEAR INFRARED CUT FILTER, DEVICE, METHOD OF MANUFACTURING COPPER-CONTAINING POLYMER, AND COPPER-CONTAINING POLYMER
  申请人：FUJIFILM Corporation

  公开号：US20180094086A1

  公开（公告）日：2018-04-05

  The near infrared absorbing composition includes: a copper-containing polymer having a copper complex site at a polymer side chain; and a solvent, in which the copper complex site includes a site multidentate-coordinated to a copper atom and at least one selected from the group consisting of a site monodentate-coordinated to a copper atom and a counter ion to a copper complex skeleton, and a polymer main chain and a copper atom at the copper complex site are bonded to each other through the site monodentate-coordinated to a copper atom or the counter ion.
• [EN] POLYMORPHS OF AVANAFIL<br/>[FR] POLYMORPHES D'AVANAFIL
  申请人：HETERO RESEARCH FOUNDATION

  公开号：WO2014174529A3

  公开（公告）日：2015-04-02