Dodecyl β-D-ribofuranoside

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: Dodecyl β-D-ribofuranoside
• 英文别名: (2R,3R,4S,5R)-2-dodecoxy-5-(hydroxymethyl)oxolane-3,4-diol
• 化学式: C₁₇H₃₄O₅
• 分子量: 318.454
• InChiKey: NXWOMTNQJLXSFE-QBPKDAKJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  22
• 可旋转键数：
  13
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  79.2
• 氢给体数：
  3
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  D-核糖 、 十二烷醇 在 silica-alumina cracking catalyst HA-HPV 作用下， 70.0 ℃ 、2.0 kPa 条件下， 反应 24.0h， 生成 Dodecyl β-D-ribofuranoside
  参考文献：
  名称：

  Synthesis of Alkyl Fructosides Using Solid Acid Catalysts. Part I: Silica-Alumina Cracking Catalysts

  摘要：

  Silica-alumina cracking catalysts and acid clays efficiently catalyze the 2-O-alkylation of D-fructose with long chain alcohols. Under the conditions applied virtually no degradation of fructose is observed. L-Sorbose and the aldopentoses also undergo silica-alumina-catalyzed alkylation. The rate of conversion is related to the solubility of the monosaccharide and the stability of the intermediate oxocarbenium ion. Best results in fructose alkylation are obtained by applying a recirculation method with butyl fructoside as soluble intermediate.

  DOI：

  10.1080/07328309608005657

文献信息

• Synthesis of Alkyl Fructosides Using Solid Acid Catalysts. Part I: Silica-Alumina Cracking Catalysts
  作者：A. T.J.W. de Goede、M. P.J. van Deurzen、I. G. van der Leij、A. M. van der Heijden、J. M.A. Baas、F. van Rantwijk、H. van Bekkum

  DOI：10.1080/07328309608005657

  日期：1996.4

  Silica-alumina cracking catalysts and acid clays efficiently catalyze the 2-O-alkylation of D-fructose with long chain alcohols. Under the conditions applied virtually no degradation of fructose is observed. L-Sorbose and the aldopentoses also undergo silica-alumina-catalyzed alkylation. The rate of conversion is related to the solubility of the monosaccharide and the stability of the intermediate oxocarbenium ion. Best results in fructose alkylation are obtained by applying a recirculation method with butyl fructoside as soluble intermediate.