3-allyl-2-(p-ethoxylphenylimino)-4-(4′-bromophenyl)-3H-thiazole

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 3-allyl-2-(p-ethoxylphenylimino)-4-(4′-bromophenyl)-3H-thiazole
• 英文别名: (2Z)-4-(4-Bromophenyl)-N-(4-ethoxyphenyl)-3-(prop-2-EN-1-YL)-2,3-dihydro-1,3-thiazol-2-imine；4-(4-bromophenyl)-N-(4-ethoxyphenyl)-3-prop-2-enyl-1,3-thiazol-2-imine
• 化学式: C₂₀H₁₉BrN₂OS
• mdl: MFCD00857036
• 分子量: 415.354
• InChiKey: XJPJDVYJOHPBKU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.6
• 重原子数：
  25
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  50.1
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  对乙氧基苯胺 、 2,4'-二溴苯乙酮 、 天然芥菜籽油 在 poly(4-vinylpyridine) 作用下， 以 乙醇 为溶剂， 反应 12.0h， 以97%的产率得到3-allyl-2-(p-ethoxylphenylimino)-4-(4′-bromophenyl)-3H-thiazole
  参考文献：
  名称：

  One-Pot, Three Component Synthesis of Thiazol-2(3H)-imines Using Poly(4-vinylpyridine) as an Efficient Reusable Heterogeneous Basic Catalyst

  摘要：

  Poly(4-vinylpyridine) is reported as a green, efficient and reusable basic catalyst for the synthesis of thiazol-2(3H)-imines under one-pot, three component reaction conditions. This simple method produces the products at room temperature in excellent yields (83-97%). Furthermore, this catalyst can be recovered by simple filtration and recycled up to four consecutive runs without any loss of its efficiency

  DOI：

  10.3987/com-14-13122

文献信息

• One-Pot, Three Component Synthesis of Thiazol-2(3H)-imines Using Poly(4-vinylpyridine) as an Efficient Reusable Heterogeneous Basic Catalyst
  作者：Asieh Yahyazadeh、Jafar Abbasi Shiran、Bohari M. Yamin、Farhad Shirini、Manouchehr Mamaghani

  DOI：10.3987/com-14-13122

  日期：——

  Poly(4-vinylpyridine) is reported as a green, efficient and reusable basic catalyst for the synthesis of thiazol-2(3H)-imines under one-pot, three component reaction conditions. This simple method produces the products at room temperature in excellent yields (83-97%). Furthermore, this catalyst can be recovered by simple filtration and recycled up to four consecutive runs without any loss of its efficiency