二十烷酸钾 | 18080-76-7

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 二十烷酸钾
• 英文名称: potassium icosanoate
• 英文别名: Kaliumeicosat；potassium arachidate；eicosanoic acid ; potassium salt；potassium n-C19H39CO2(1-)；Eicosansaeure; Kaliumsalz；potassium;icosanoate
• CAS: 18080-76-7
• 化学式: C₂₀H₃₉O₂*K
• 分子量: 350.627
• InChiKey: JFZDUSDRGGZYDF-UHFFFAOYSA-M

计算性质

• 辛醇/水分配系数(LogP)：
  2.78
• 重原子数：
  23
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.95
• 拓扑面积：
  40.1
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2915900090

反应信息

• 作为反应物：
  描述：

  rasagiline-N-chloromethyl formate 、 二十烷酸钾 在 四丁基碘化铵 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 以43.78%的产率得到methyl ((rasagiline-N-formyl)oxy)icosanoate
  参考文献：
  名称：

  LONG-ACTING RASAGILINE PRODRUG, PREPARATION METHOD AND USE THEREOF

  摘要：

  提供了拉沙吉林的长效前药、制备方法及其用途。拉沙吉林的长效前药具有如下结构式（I），其中T为空缺，或T选自（II）；R1和R2中的每一个独立选自H、D和烷基；W为空缺，或W选自（CH2）n，其中n为1至15之间的整数；X为空缺，或X选自（CH2）m，其中m为1至10之间的整数；Y为空缺，或Y选自-C(=O)NH-、-NHC(=O)-；R3选自取代或未取代的C1-C30烷基、取代或未取代的C2-C30烯基、取代或未取代的C2-C30炔基、取代或未取代的C3-C30环烷基、胆烷脂肪基、-R3a-C(=O)O-R3b、-R3a-OC(=O)-R3b、-R3a-C(=O)NH-R3b、-R3a-NHC(=O)-R3b、-R3a-S(=O)1-2O-R3b和-R3a-OS(=O)1-2-R3b。所提供的拉沙吉林前药具有高熔点和低溶解度，如果以注射剂形式制备，则可在体内形成药物储库，延长前药在体内的释放速率，达到长效治疗的效果。

  公开号：

  EP3674289A1

文献信息

• Fuel oil additive and fuel oil products containing the fuel oil additive
  申请人：——

  公开号：US20040065002A1

  公开（公告）日：2004-04-08

  The present invention provides a fuel oil additive capable of effectively improving the quality of fuel oils, which comprises an oil-soluble metal salt of organic acid having the general formula MR, where R is an organic acid radical and the corresponding organic acid is a C 1 -C 40 saturated or unsaturated fatty acid, naphthenic acid, aromatic acid or alkylphenol, M is a metal cation and the corresponding metal is an alkali metal, alkali-earth metal, rare-earth metal, transition metal, or the like. The present invention also provides fuel oil products added to the fuel oil additive, including gasoline, diesel oil, kerosene, heavy oil, resid, or the like. The present invention especially provides a gasoline antiknock agent and a gasoline having excellent antiknock property, and this kind of gasoline antiknock agent is characteristic of effectiveness, economy, safety, no environmental pollution, no toxicity to human body, no adverse effect on parts of automobile engine, use convenience, and the like.

  本发明提供了一种能够有效改善燃料油质量的燃料油添加剂，它包括通式为 MR 的有机酸的油溶性金属盐，其中 R 是有机酸基，相应的有机酸是 C 1 -C 40 饱和或不饱和脂肪酸、环烷酸、芳香酸或烷基酚，M 是金属阳离子，相应的金属是碱金属、碱土金属、稀土金属、过渡金属或类似金属。本发明还提供添加到燃料油添加剂中的燃料油产品，包括汽油、柴油、煤油、重油、渣油或类似产品。本发明特别提供了一种汽油抗爆剂和一种抗爆性能优异的汽油，这种汽油抗爆剂具有高效、经济、安全、无环境污染、对人体无毒性、对汽车发动机部件无不良影响、使用方便等特点。
• An infrared reflection spectroscopy study of oriented cadmium arachidate monolayer films on evaporated silver
  作者：D. L. Allara、J. D. Swalen

  DOI：10.1021/j100211a029

  日期：1982.7
• Self-Assembled Multibilayers of Europium Alkanoates:  Structure, Photophysics, and Mesomorphic Behavior
  作者：Haolong Li、Weifeng Bu、Wei Qi、Lixin Wu

  DOI：10.1021/jp053980o

  日期：2005.11.1

  A series of europium alkanoates (Cn-1H2n-1CO2)(3)EU, (n = 14, 16, 18, 20) have been synthesized and characterized in detail. X-ray diffraction and Fourier transform infrared spectroscopic measurements confirm the multibilayer structure of these homologues. In such bilayers, the europium ionic layers are well separated by the highly ordered alkyl chains which are in an all-trans conformation and perpendicular to both sides of the europium ionic layers. There is a mixed-coordination type of chelating bidentate and bridging bidentate between the carboxylate groups and the europium ions. All samples exhibit characteristic emission of europium, though the luminescent intensity has been partly quenched by the carboxylate groups. Differential scanning caloritnetry (DSC) shows multiple melting points for these homologues, and temperature-dependent X-ray diffraction measurements also confirm the existence of the mesophase on heating. This mesophase is not truly liquid crystalline, but is similar to the smectic A phase of organic rodlike molecules. Meanwhile, it seems that with increasing atomic number of lanthanide ions, longer alkyl chains will be required to form such a mesophase for the corresponding lanthanide alkanoates.
• SCHATOWITZ, BERT;GERCKEN, GUNTHER, J. CHROMATOGR., 409,(1987) 43-54
  作者：SCHATOWITZ, BERT、GERCKEN, GUNTHER

  DOI：——

  日期：——
• EP1080071A4
  申请人：——

  公开号：EP1080071A4

  公开（公告）日：2002-06-26