7S-amino-2-(2-hydroxy-3-methoxy-6-methylbenzoyl)-2-methyl[1,3]oxazocane-4,8-dione

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 7S-amino-2-(2-hydroxy-3-methoxy-6-methylbenzoyl)-2-methyl[1,3]oxazocane-4,8-dione
• 英文别名: pyriferine C；Pyriferine C；(7R)-7-amino-2-(2-hydroxy-3-methoxy-6-methylbenzoyl)-2-methyl-1,3-oxazocane-4,8-dione
• 化学式: C₁₆H₂₀N₂O₆
• 分子量: 336.345
• InChiKey: SUPKVFVCJYCZRK-MGFKIWBESA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  24
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.44
• 拓扑面积：
  128
• 氢给体数：
  3
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  7S-amino-2-(2-hydroxy-3-methoxy-6-methylbenzoyl)-2-methyl[1,3]oxazocane-4,8-dione 在 盐酸 、 水 作用下， 反应 24.0h， 生成 DL-谷氨酸
  参考文献：
  名称：

  Alkaloids from the Mushroom Pseudobaeospora pyrifera, Pyriferines A−C

  摘要：

  Three novel alkaloids (1-3), named pyriferines A-C, were isolated from fruiting bodies of Pseudobaeospora pyrifera. They possess an unusual eight-membered N/O-acetal ring, derived from L-glutamtic acid, that is connected to an enolized 1,3-diketo moiety. The structures were determined by spectroscopic methods, and the absolute configuration of the glutamic acid moiety was established using GC-MS after Mosher-type derivatization.

  DOI：

  10.1021/np800365f

文献信息

• Alkaloids from the Mushroom <i>Pseudobaeospora pyrifera</i>, Pyriferines A−C
  作者：Dang Ngoc Quang、Peter Spiteller、Andrea Porzel、Jürgen Schmidt、Torsten Geissler、Norbert Arnold、Ludger Wessjohann

  DOI：10.1021/np800365f

  日期：2008.9.1

  Three novel alkaloids (1-3), named pyriferines A-C, were isolated from fruiting bodies of Pseudobaeospora pyrifera. They possess an unusual eight-membered N/O-acetal ring, derived from L-glutamtic acid, that is connected to an enolized 1,3-diketo moiety. The structures were determined by spectroscopic methods, and the absolute configuration of the glutamic acid moiety was established using GC-MS after Mosher-type derivatization.