2,2-dimethyl-3R-(1',2'-dibromo-2',2'-difluoroethyl)-cyclopropane-1R-carboxylic acid

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 2,2-dimethyl-3R-(1',2'-dibromo-2',2'-difluoroethyl)-cyclopropane-1R-carboxylic acid
• 英文别名: (1R,3R)-3-(1,2-dibromo-2,2-difluoroethyl)-2,2-dimethylcyclopropane-1-carboxylic acid
• 化学式: C₈H₁₀Br₂F₂O₂
• 分子量: 335.971
• InChiKey: ZSLSWXUSULSWQT-QRHDOFTISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.88
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  S-烯丙醇酮 、 2,2-dimethyl-3R-(1',2'-dibromo-2',2'-difluoroethyl)-cyclopropane-1R-carboxylic acid 生成 (1R,3R)-3-(1,2-Dibromo-2,2-difluoro-ethyl)-2,2-dimethyl-cyclopropanecarboxylic acid (S)-3-allyl-2-methyl-4-oxo-cyclopent-2-enyl ester
  参考文献：
  名称：

  DE2742546

  摘要：

  公开号：
• 作为产物：
  描述：

  2,2-dimethyl-3R-(2',2'-difluorovinyl)-cyclopropane-1R-carboxylic acid 在 溴 作用下， 以 四氯化碳 、 二氯甲烷 为溶剂， 生成 2,2-dimethyl-3R-(1',2'-dibromo-2',2'-difluoroethyl)-cyclopropane-1R-carboxylic acid
  参考文献：
  名称：

  Polyhalogenated carboxylic acids

  摘要：

  化合物的名称为Novel polyhalogenated cyclopropane carboxylic acid compounds，化学式为##STR1## 其中X.sub.1 可选自氢、氟、氯和溴，X.sub.2 可选自氟、氯和溴，X.sub.3 可选自氯、溴和碘，R 可选自羟基、卤素、1到7个碳原子的烷氧基或R代表OM基团，其中M可选自金属、有机碱、有机羧酸酰基和该酸的酰基，其可能的异构体形式有用于制造其杀虫酯中间体的，并且具有抗真菌和生物杀灭活性。

  公开号：

  US04179575A1

文献信息

• Novel cyclopropane carboxylic acid esters
  申请人：Roussel Uclaf

  公开号：US04224227A1

  公开（公告）日：1980-09-23

  Novel cyclopropane carboxylic acid esters of the formula ##STR1## wherein X.sub.1 is selected from the group consisting of hydrogen, fluorine, chlorine and bromine, X.sub.2 is selected from the group consisting of fluorine, chlorine and bromine, X.sub.3 is selected from the group consisting of chlorine, bromine and iodine and R is selected from the group consisting of ##STR2## and benzyl optionally substituted with at least one member of the group consisting of alkyl of 1 to 4 carbon atoms, alkenyl of 2 to 6 carbon atoms, alkenyloxy of 2 to 6 carbon atoms, alkadienyl of 4 to 8 carbon atoms, methylenedioxy, benzyl and halogens, R.sub.1 is selected from the group consisting of hydrogen and methyl, R.sub.2 is selected from the group consisting of monocyclic aryl and --CH.sub.2 --C.tbd.CH,R.sub.3 is an aliphatic of 2 to 6 carbon atoms having at least one double bond, R.sub.4 is selected from the group consisting of hydrogen, --CN and --C.tbd.CH, R.sub.5 is selected from the group consisting of chlorine and methyl, n is 0, 1 or 2, R.sub.6, R.sub.7, R.sub.8 and R.sub.9 are individually selected from the group consisting of hydrogen, chlorine and methyl and S/I indicates that the ring may be aromatic, dihydro or tetrahydro having pesticidal properties, and a process for their preparation.

  化合物的名称为新颖的环丙烷羧酸酯，其化学式为##STR1## 其中X.sub.1从氢、氟、氯和溴的群体中选择，X.sub.2从氟、氯和溴的群体中选择，X.sub.3从氯、溴和碘的群体中选择，R从##STR2##和苄基中选择，后者可选择用1至4个碳原子的烷基、2至6个碳原子的烯基、2至6个碳原子的烯氧基、4至8个碳原子的烯二烯基、亚甲二氧基、苯甲基和卤素中的至少一种成员替代，R.sub.1从氢和甲基的群体中选择，R.sub.2从单环芳基和--CH.sub.2 --C.tbd.CH的群体中选择，R.sub.3是具有至少一个双键的2至6个碳原子的脂肪基，R.sub.4从氢、--CN和--C.tbd.CH的群体中选择，R.sub.5从氯和甲基的群体中选择，n为0、1或2，R.sub.6、R.sub.7、R.sub.8和R.sub.9分别从氢、氯和甲基的群体中选择，S/I表示环可以是具有杀虫性质的芳香、二氢或四氢，并提供了它们的制备方法。
• Phthalimidomethyl cyclopropane carboxylic acid esters
  申请人：Roussel Uclaf

  公开号：US04231932A1

  公开（公告）日：1980-11-04

  Novel cyclopropane carboxylic acid esters of the formula ##STR1## wherein X.sub.1 is selected from the group consisting of hydrogen, fluorine, chlorine and bromine, X.sub.2 is selected from the group consisting of fluorine, chlorine and bromine, X.sub.3 is selected from the group consisting of chlorine, bromine and iodine and R is selected from the group consisting of ##STR2## and benzyl optionally substituted with at least one member of the group consisting of alkyl of 1 to 4 carbon atoms, alkenyl of 2 to 6 carbon atoms, alkenyloxy of 2 to 6 carbon atoms, alkadienyl of 4 to 8 carbon atoms, methylenedioxy, benzyl and halogens, R.sub.1 is selected from the group consisting of hydrogen and methyl, R.sub.2 is selected from the group consisting of monocyclic aryl and --CH.sub.2 --C.tbd.CH,R.sub.3 is an aliphatic of 2 to 6 carbon atoms having at least one double bond, R.sub.4 is selected from the group consisting of hydrogen, --CN and --C.tbd.CH, R.sub.5 is selected from the group consisting of chlorine and methyl, n is 0, 1 or 2, R.sub.6, R.sub.7, R.sub.8 and R.sub.9 are individually selected from the group consisting of hydrogen, chlorine and methyl and S/I indicates that the ring may be aromatic, dihydro or tetrahydro having pesticidal properties, and a process for their preparation.

  化合物的名称为新型环丙烷羧酸酯，其化学式为##STR1##其中X1为氢、氟、氯和溴中的一种，X2为氟、氯和溴中的一种，X3为氯、溴和碘中的一种，R为##STR2##和苄基，可选地被替换为1至4个碳原子的烷基，2至6个碳原子的烯基，2至6个碳原子的烯氧基，4至8个碳原子的烯二烷基，亚甲二氧基，苯甲基和卤素中的至少一个成员。R1为氢和甲基中的一种，R2为单环芳基和--CH2--C.tbd.CH中的一种，R3为具有至少一个双键的2至6个碳原子的脂肪基，R4为氢、--CN和--C.tbd.CH中的一种，R5为氯和甲基中的一种，n为0、1或2，R6、R7、R8和R9分别为氢、氯和甲基中的一种，S/I表示环可以是芳香、二氢或四氢，具有杀虫性能，以及其制备方法。
• US4179575A
  申请人：——

  公开号：US4179575A

  公开（公告）日：1979-12-18
• US4224227A
  申请人：——

  公开号：US4224227A

  公开（公告）日：1980-09-23
• US4231932A
  申请人：——

  公开号：US4231932A

  公开（公告）日：1980-11-04