2,2′-bis(4-methylphenyl)biphenyl

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,2′-bis(4-methylphenyl)biphenyl
• 英文别名: 1-Methyl-4-[2-[2-(4-methylphenyl)phenyl]phenyl]benzene
• 化学式: C₂₆H₂₂
• 分子量: 334.461
• InChiKey: PKNWQDBTUJGANS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.2
• 重原子数：
  26
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  2,2′-bis(4-methylphenyl)biphenyl 在 三氟甲磺酸 、 2,3-二氯-5,6-二氰基-1,4-苯醌 作用下， 以 二氯甲烷 为溶剂， 以55%的产率得到2-(4-Methylphenyl)triphenylene
  参考文献：
  名称：

  Palladium-Catalyzed Double-Suzuki–Miyaura Reactions Using Cyclic Dibenziodoniums: Synthesis of o-Tetraaryls

  摘要：

  Palladium-catalyzed double-Suzuki-Miyaura couplings between cyclic dibenziodoniums and arylboronic acids have been developed. As such, a wide range of otetraaryls were synthesized in good to excellent yields of 22-94%. Furthermore, tetraphenylene was prepared in 21% isolated yield with 2,2'-biphenyldiboronic acid by using this method.

  DOI：

  10.1021/acs.joc.5b02255
• 作为产物：
  描述：

  dibenzo[b,d]iodol-5-ium trifluoromethanesulfonate 、 4-甲苯硼酸 在 potassium phosphate 、 bis(dibenzylideneacetone)-palladium⁽⁰⁾ 作用下， 以 二氯甲烷 为溶剂， 反应 12.0h， 以83%的产率得到2,2′-bis(4-methylphenyl)biphenyl
  参考文献：
  名称：

  Palladium-Catalyzed Double-Suzuki–Miyaura Reactions Using Cyclic Dibenziodoniums: Synthesis of o-Tetraaryls

  摘要：

  Palladium-catalyzed double-Suzuki-Miyaura couplings between cyclic dibenziodoniums and arylboronic acids have been developed. As such, a wide range of otetraaryls were synthesized in good to excellent yields of 22-94%. Furthermore, tetraphenylene was prepared in 21% isolated yield with 2,2'-biphenyldiboronic acid by using this method.

  DOI：

  10.1021/acs.joc.5b02255

文献信息

• Desulfurization of dibenzothiophene and dibenzothiophene sulfone via Suzuki–Miyaura type reaction: Direct access to o-terphenyls and polyphenyl derivatives
  作者：Rubén Gutiérrez-Ordaz、Juventino J. García

  DOI：10.1016/j.poly.2018.08.008

  日期：2018.11

  between the desulfurization of the corresponding substrates via a hydrodesulfurization (HDS) or by a hydrodesulfurative cross-coupling (HDSCC) reaction. Furthermore, in the absence of water sulfur-free poly-phenylic compounds were obtained in good yields as a result of a Suzuki–Miyaura type reaction, being the main product in most of the cases the corresponding o-terphenyl derivative, these products are

  摘要镍前体[Ni（dpepe）Cl2]在碱存在下介导了二苯并噻吩（DBT）或二苯并噻吩砜（DBTO2）与多种苯基硼酸的反应性。该反应在相对温和的条件下（70–100°C）在水性介质中进行。对反应性的研究揭示了水作为氢源的作用，并显示了通过加氢脱硫（HDS）或加氢脱硫交叉偶联（HDSCC）反应对相应底物进行脱硫之间的竞争。此外，在没有水的情况下，由于铃木-宫浦（Suzuki-Miyaura）型反应而获得了高收率的无硫聚苯基化合物，在大多数情况下，它们是主要的产物，相应的邻三联苯衍生物
• Palladium-Catalyzed Double-Suzuki–Miyaura Reactions Using Cyclic Dibenziodoniums: Synthesis of <i>o</i>-Tetraaryls
  作者：Yanxia Zhang、Jianwei Han、Zhen-Jiang Liu

  DOI：10.1021/acs.joc.5b02255

  日期：2016.2.19

  Palladium-catalyzed double-Suzuki-Miyaura couplings between cyclic dibenziodoniums and arylboronic acids have been developed. As such, a wide range of otetraaryls were synthesized in good to excellent yields of 22-94%. Furthermore, tetraphenylene was prepared in 21% isolated yield with 2,2'-biphenyldiboronic acid by using this method.