N,N'-di(methoxycarbonyl)(4-bromophenyl)-methanediamine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N,N'-di(methoxycarbonyl)(4-bromophenyl)-methanediamine
• 英文别名: N,N'-di(methoxycarbonyl)(4-bromophenyl)methanediamine；methyl N-[(4-bromophenyl)[(methoxycarbonyl)amino]methyl]carbamate；methyl N-[(4-bromophenyl)-(methoxycarbonylamino)methyl]carbamate
• 化学式: C₁₁H₁₃BrN₂O₄
• 分子量: 317.139
• InChiKey: VIZXTCSQIBOUMM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2
• 重原子数：
  18
• 可旋转键数：
  5
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.27
• 拓扑面积：
  76.7
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  (Z)-1-(trimethylsilyl)dodec-1-ene 、 N,N'-di(methoxycarbonyl)(4-bromophenyl)-methanediamine 在 silver hexafluoroantimonate 、 platinum(II) chloride 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 24.0h， 以24%的产率得到
  参考文献：
  名称：

  Platinum-catalyzed allylation of carbon electrophiles with alkenylsilanes

  摘要：

  In the presence of catalytic amounts of PtCl2 and AgSbF6, (Z)-alkenylsilanes react with various carbon electrophiles at the gamma-position to give allylation products. A plausible mechanism for the Pt-catalyzed allylation involves alkene migration of alkenylsilanes to allylsilanes and subsequent allylation of carbon electrophiles. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.12.077
• 作为产物：
  描述：

  对溴苯甲醛 、 氨基甲酸甲酯 在 硫酸 作用下， 以 甲苯 为溶剂， 反应 1.0h， 以9%的产率得到N,N'-di(methoxycarbonyl)(4-bromophenyl)-methanediamine
  参考文献：
  名称：

  Platinum-catalyzed allylation of carbon electrophiles with alkenylsilanes

  摘要：

  In the presence of catalytic amounts of PtCl2 and AgSbF6, (Z)-alkenylsilanes react with various carbon electrophiles at the gamma-position to give allylation products. A plausible mechanism for the Pt-catalyzed allylation involves alkene migration of alkenylsilanes to allylsilanes and subsequent allylation of carbon electrophiles. (C) 2014 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2014.12.077

文献信息

• Platinum-catalyzed allylation of carbon electrophiles with alkenylsilanes
  作者：Hidenori Kinoshita、Ryosuke Kizu、Gen Inoue、Masayuki Fujimoto、Masanori Saito、Junji Ichikawa、Akira Hosomi、Katsukiyo Miura

  DOI：10.1016/j.tetlet.2014.12.077

  日期：2015.1

  In the presence of catalytic amounts of PtCl2 and AgSbF6, (Z)-alkenylsilanes react with various carbon electrophiles at the gamma-position to give allylation products. A plausible mechanism for the Pt-catalyzed allylation involves alkene migration of alkenylsilanes to allylsilanes and subsequent allylation of carbon electrophiles. (C) 2014 Elsevier Ltd. All rights reserved.
• Regioselective Allylation of Carbon Electrophiles with Alkenyl­silanes under Dual Catalysis by Cationic Platinum(II) Species
  作者：Katsukiyo Miura、Hidenori Kinoshita、Ryosuke Kizu、Masahiro Horikoshi、Gen Inoue、Masayuki Fujimoto、Masanori Saito、Junji Ichikawa、Akira Hosomi

  DOI：10.1055/s-0035-1560380

  日期：——

  In the presence of catalytic amounts of platinum(II) chloride and silver(I) hexafluoroantimonate, (Z)-alkenylsilanes reacted with various carbon electrophiles (acetals, aminals, carboxylic anhydrides, alkyl chlorides, etc.) at the -position to give allylation products. A plausible mechanism for the platinum-catalyzed allylation involves alkene migration of alkenylsilanes to allylsilanes and subsequent allylation of carbon electrophiles, both of which are catalyzed by a cationic platinum(II) species.