6-(tetrahydrofuran-2-yl)hexan-1-ol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 6-(tetrahydrofuran-2-yl)hexan-1-ol
• 英文别名: 2-(6-hydroxyhexyl)tetrahydrofuran；6-(Oxolan-2-yl)hexan-1-ol
• 化学式: C₁₀H₂₀O₂
• 分子量: 172.268
• InChiKey: KANXHFLJQBZBGE-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  12
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  29.5
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  1,10-癸二醇 在 phenyl-λ³-iodanediyl bis(3-chlorobenzoate) 、 碘 作用下， 以 1,2-二氯乙烷 为溶剂， 反应 18.0h， 生成 bis-1,2-tetrahydrofurylethane 、 6-(tetrahydrofuran-2-yl)hexan-1-ol
  参考文献：
  名称：

  分子内碘催化 C(sp3)-H 氧化作为合成四氢呋喃的多功能工具

  摘要：

  脂肪族伯醇和仲醇的第一个碘催化环化反应通过分子内 C(sp 3 )-H 活化获得四氢呋喃。该反应在使用泛光灯或日光的温和反应下进行。

  DOI：

  10.1002/ejoc.202100652

文献信息

• C( <i>sp</i> ³ )−C( <i>sp</i> ³ ) Cross‐Coupling of Alkyl Bromides and Ethers Mediated by Metal and Visible Light Photoredox Catalysis
  作者：Marilia S. Santos、Arlene G. Corrêa、Márcio W. Paixão、Burkhard König

  DOI：10.1002/adsc.202000167

  日期：2020.6.15

  We report a C(sp 3)−C(sp 3) cross‐coupling of alkyl bromides and alkyl chlorides with ethers by dual photoredox‐nickel catalysis. The catalytic system comprises of the organic photocatalyst 1,2,3,5‐tetrakis(carbazol‐9‐yl)‐4,6‐dicyanobenzene (4‐CzIPN) and bench stable nickel (II) acetylacetonate in the presence of visible‐light, providing the coupling products in up to 92% yield. Preliminary mechanistic

  我们报道了通过双光氧化还原镍催化的烷基溴和烷基氯与醚的C（sp 3）-C（sp 3）交叉偶联。催化体系由可见光下的有机光催化剂1,2,3,5-四（咔唑-9-基）-4,6-二氰基苯（4-CzIPN）和稳定的乙酰丙酮镍（II）组成，以高达92％的产率提供耦合产品。初步的机理研究表明，存在两个催化循环，以及偶合伙伴结构中存在的卤原子产生溴或氯自由基的光生化。卤化物自由基介导氢原子转移事件，从而避免了额外的HAT催化剂的需要。
• Deplacements homolytiques intramoleculaires. 12-decomposition induite de peroxydes ethyleniques : influence de la longueur de la chaine
  作者：M.J. Bourgeois、B. Maillard、E. Montaudon

  DOI：10.1016/s0040-4020(01)82080-9

  日期：1986.1

  Products analyses of the thermolyses of the peroxides CH2=CH-(CH2)n OOtBu, , (n= 1-5) showed that an induced decomposition of occured for n=l,2,3,4. Free radical additions of THF, carbon tetrachloride, bromotrichloromethane to have been performed at lower temperature ; they allowed, through the isolation of an adduct peroxide, at least in one case for each peroxide, to prove that a two-steps mechanism

  过氧化物CH 2＝ CH-（CH 2）n OOtBu ，（n ＝ 1-5）的热解的产物分析表明，在n ＝1、2、3、4时发生了诱导的分解。THF，四氯化碳，溴三氯甲烷的自由基加成已在较低温度下进行；他们通过分离过氧化物加合物，至少在每种情况下对一种过氧化物进行了分离，证明了两步机理（自由基Z·加到双键上，分子内均质置换）参与了诱导的三价氧的分解。。可以估计这些S H i反应的速率常数的数量级。
• SUPPORTED NON-METALLOCENE OLEFIN POLYMERIZATION CATALYST, AND PREPARATION AND USE THEREOF
  申请人：Yangzi Petrochemical Company Co., Ltd.

  公开号：EP1829897B1

  公开（公告）日：2014-12-10
• Supported Nonmetallocene Olefin Polymerization Catalyst, Preparation Method and Use Thereof
  申请人：Dai Houliang

  公开号：US20080227936A1

  公开（公告）日：2008-09-18

  The present invention provides a method for supporting a nonmetallocene olefin polymerization catalyst, comprising the following steps: a carrier reacts with a chemical activator to obtain a modified carrier; a magnesium compound is dissolved in a tetrahydrofuran-alcohol mixed solvent to form a solution, then the modified carrier is added to the solution to perform a reaction, then filtered and washed, dried and suction dried to prepare a composite carrier; a nonmetallocene olefin polymerization catalyst is dissolved in a solvent, and then reacts with said composite carrier, then is washed and filtered, dried and suction dried, to prepare a supported nonmetallocene olefin polymerization catalyst. The present invention further relates to a supported nonmetallocene olefin polymerization catalyst as prepared by this method. The present invention further relates to the use of the supported nonmetallocene olefin polymerization catalyst in an olefin polymerization and an olefin copolymerization between two or more different olefins. In one specific embodiment, the present invention relates to the use of the supported nonmetallocene olefin polymerization catalyst in a slurry ethylene polymerization. The present invention provides a new type of catalyst that improves the polymer morphology, increases polymer bulk density and enhances polymerization activity.
• US7875568B2
  申请人：——

  公开号：US7875568B2

  公开（公告）日：2011-01-25