ethyl 4-(methyldimethoxysilyl)benzoate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: ethyl 4-(methyldimethoxysilyl)benzoate
• 英文别名: Ethyl 4-[dimethoxy(methyl)silyl]benzoate；ethyl 4-[dimethoxy(methyl)silyl]benzoate
• 化学式: C₁₂H₁₈O₄Si
• 分子量: 254.358
• InChiKey: SEXPQGMHDBZHGT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.44
• 重原子数：
  17
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  44.8
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  甲基二甲氧基硅烷 、 对碘苯甲酸乙酯 在 acethylacetonato(1,5-cyclooctadiene)rhodium(I) 三乙胺 作用下， 以 N,N-二甲基甲酰胺 为溶剂， 反应 4.0h， 以59%的产率得到苯甲酸乙酯
  参考文献：
  名称：

  Synthesis of aryltriethoxysilanes via rhodium(I)-catalyzed cross-coupling of aryl electrophiles with triethoxysilane

  摘要：

  The general and efficient silylation of aryl halides has been developed utilizing triethoxysilane and a rhodium catalyst, The substrate scope is broad and includes ortho-, meta-, and para-substituted electron-rich and -deficient aryl iodides. In addition, the silylation of aryl bromides and fluoroalkanesulfonates proceeded in the presence of tetra-n-butylammonium iodide. (C) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2007.02.103

文献信息

• Synthesis of aryltriethoxysilanes via rhodium(I)-catalyzed cross-coupling of aryl electrophiles with triethoxysilane
  作者：Miki Murata、Hiyoruki Yamasaki、Tsukasa Ueta、Masayuki Nagata、Masanori Ishikura、Shinji Watanabe、Yuzuru Masuda

  DOI：10.1016/j.tet.2007.02.103

  日期：2007.5

  The general and efficient silylation of aryl halides has been developed utilizing triethoxysilane and a rhodium catalyst, The substrate scope is broad and includes ortho-, meta-, and para-substituted electron-rich and -deficient aryl iodides. In addition, the silylation of aryl bromides and fluoroalkanesulfonates proceeded in the presence of tetra-n-butylammonium iodide. (C) 2007 Elsevier Ltd. All rights reserved.