二甘醇己二酸酯 | 58984-19-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 二甘醇己二酸酯
• 英文名称: Diethylene glycol adipic acid
• 英文别名: hexanedioic acid;2-(2-hydroxyethoxy)ethanol
• CAS: 58984-19-3
• 化学式: C10H20O7
• 分子量: 252.26
• InChiKey: FRXFBIWLAJRBQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  17
• 可旋转键数：
  9
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  124
• 氢给体数：
  4
• 氢受体数：
  7

反应信息

• 作为反应物：
  描述：

  乙酸乙烯酯 、 N-乙烯基吡咯烷酮 、 偶氮二异丁腈 、 二甘醇己二酸酯 以 甲苯 、 乙酸乙酯 为溶剂， 反应 4.0h， 生成 VP/VAc共聚物
  参考文献：
  名称：

  Water-reducible, water-remoistenable adhesive composition

  摘要：

  水还原、水再湿润粘合剂组合物是由以下混合物制成：（a）醋酸乙烯聚合物的水乳液，（b）醋酸乙烯和乙烯吡咯烷共聚物的有机溶剂溶液，其中分散有糊精，以及（c）酯树脂粘合剂的水乳液。

  公开号：

  US04719264A1

文献信息

• Sustained release of active molecules from polymers topically applied to skin or hair
  申请人：Giacomoni Paolo

  公开号：US20060088489A1

  公开（公告）日：2006-04-27

  The invention relates to a polymer for topical delivery of biologically active ingredients, the polymer comprising at least one moiety: U-B-A in which U represents a physiologically acceptable unit of an oligomer or polymer, A represents a biologically active component, and B represents one or more bond(s) linking A to U, which bond is capable of being disrupted by a biological, physical or chemical process occurring in or on skin.

  该发明涉及一种用于局部传递生物活性成分的聚合物，该聚合物包括至少一种基团：U-B-A，其中U代表寡聚物或聚合物的生理可接受的单元，A代表生物活性成分，B代表将A与U连接的一个或多个键，该键能够被在皮肤内或外发生的生物、物理或化学过程破坏。
• DENTAL COMPOSITE MATERIALS COMPRISING TRICYCLIC PLASTICIZERS
  申请人：VOCO GmbH

  公开号：US20130203884A1

  公开（公告）日：2013-08-08

  The present invention relates to dental polymerizable composite materials (curable dental compositions) comprising one or more plasticizers comprising a tricyclic structural element, to dental materials (polymers), obtainable by curing from the dental polymerizable composite materials comprising one or more plasticizers comprising a tricyclic structural element, to processes for producing a dental material and to dental curable composite materials for use in a therapeutic method in the production of a dental material.

  本发明涉及牙科可聚合复合材料（可固化的牙科组合物），包括一种或多种包含三环结构元素的增塑剂，以及通过从包含一种或多种包含三环结构元素的增塑剂的牙科可聚合复合材料固化获得的牙科材料（聚合物），用于制备牙科材料的工艺和用于治疗方法中的牙科可固化复合材料的生产。
• NOVEL PEPTIDES, USE THEREOF IN COSMETIC AND COSMECEUTIC APPLICATIONS, AND COMPOSITIONS COMPRISING SAME
  申请人：Hocquaux Michel

  公开号：US20100310484A1

  公开（公告）日：2010-12-09

  A peptide of formula I (SEQ ID NO: 1): Lip-A-Gly-His-B-R (I) wherein: Lip is a lipoyl residue of R or S configuration; A is absent or is a lysine residue of configuration L or D; GIy is a glycine residue; His is a histidine residue of configuration L or D; B is a lysine residue of configuration L or D, or a lysine residue of configuration L or D in which the NH2 group of the side chain comprises a modification, wherein said modification is (i) a replacement with a hydrogen or (ii) a modification with a protecting group selected from the group consisting of acetyl, benzoyl, tosyl, sulfonyl benzene, benzyloxycarbonyle and palmitoyl; wherein R is O(Z) or N(Z′)(Z′), and wherein Z, Z′ and Z′ are independently of each other a hydrogen or a protecting group selected from the group consisting of methyl, ethyl, propyl, phenyl, hexyl, decyl and hexadecyl, or a racemate, an enantiomer or a diastereomer thereof, or a mixture thereof, or a salt thereof. A peptide of formula II (SEQ ID NO: 2): Lip-A-His-B-C-Trp-R (II) wherein: Lip is a lipoyl residue of configuration R or S; His is a histidine residue of configuration L; Trp is a tryptophane residue of configuration L; A is absent, is an amino acid residue of configuration L or D selected from the group consisting of a lysine residue, an alanine residue, a glutamic acid residue and a glycine residue, or is a spacer of formula: NH—(CH2)n-CO— wherein n is an integer comprised between 2 and 14; B is an aromatic amino acid residue of configuration D selected from the group consisting of a phenylalanine residue, a homophenylalanine residue, a tryptophane residue, a β-(1-Naphthyl)-alanine residue, a β-(2-Naphthyl)-alanine residue and a phenylglycine residue; C is a basic amino acid residue of configuration L selected from the group consisting of an arginine residue, a lysine residue, an ornithine residue and a homoarginine residue; wherein R is O(Z) or N(Z′)(Z′),

  序列编号为1的肽类分子式为I：Lip-A-Gly-His-B-R，其中：Lip是R或S构型的脂肪酰残基；A不存在或是L或D构型的赖氨酸残基；Gly是甘氨酸残基；His是L或D构型的组氨酸残基；B是L或D构型的赖氨酸残基，或是其侧链的NH2基团经修饰后的赖氨酸残基，该修饰是(i)用氢原子替换或(ii)用保护基选自乙酰基、苯甲酰基、托磺基苯、苄氧羰基和棕榈酰基的保护基进行修饰；其中R是O(Z)或N(Z′)(Z′)，Z、Z′和Z′独立地选自氢原子或选自甲基、乙基、丙基、苯基、己基、癸基和十六烷基的保护基，或是它们的外消旋体、对映体或二对映异构体的混合物，或是其盐。 序列编号为2的肽类分子式为II：Lip-A-His-B-C-Trp-R，其中：Lip是R或S构型的脂肪酰残基；His是L构型的组氨酸残基；Trp是L构型的色氨酸残基；A不存在，是选自L或D构型的氨基酸残基的赖氨酸残基、丙氨酸残基、谷氨酸残基和甘氨酸残基，或是分子式为NH—(CH2)n-CO—，其中n为2至14之间的整数的间隔物；B是D构型的芳香族氨基酸残基，选自苯丙氨酸残基、同型苯丙氨酸残基、色氨酸残基、β-(1-萘基)-丙氨酸残基、β-(2-萘基)-丙氨酸残基和苯基甘氨酸残基；C是L构型的碱性氨基酸残基，选自精氨酸残基、赖氨酸残基、鸟氨酸残基和同型精氨酸残基；其中R是O(Z)或N(Z′)(Z′)。
• Process for preparing integral skin microcellular polyester base polyurethane elastomers, the elastomers per se isocyanate curable compositions and two component combinations for producing the elastomers and cast shoe soles attached to shoe uppers
  申请人：PLASTICS TECHNOLOGY ASSOCIATES, INC.

  公开号：EP0035389A2

  公开（公告）日：1981-09-09

  Synthesis of integral skinmicrocellular polyurethane elastomers by reacting hydroxyl-terminated aliphatic polyesters with symmetrical diisocyanates, prepolymers of these isocyanates such as derived form p,p'-diphenylmethane diisocyanate and an aliphatic glycol and mixtures thereof, these are polymerized in the presence of an organic blowing agent, and one or more plasticizers such as of the formulae and further enhancement of the results is brought about by the presence of catalysts and cell regulating agents, such as dimethylpolysiloxanes; the obtained elastomers are useful, such as for shoe soles and in the manufacture of other products, e.g., vibration dampening devices, floatation devices, gaskets and the like.

  通过使羟基封端脂肪族聚酯与对称二异氰酸酯、这些异氰酸酯的预聚物（如 p,p'-二苯基甲烷二异氰酸酯和脂肪族乙二醇及其混合物）反应，合成整体皮膜微孔聚氨酯弹性体。 和 催化剂和细胞调节剂（如二甲基聚硅氧烷）的存在可进一步提高效果；获得的弹性体可用于鞋底和制造其他产品，如减震装置、漂浮装置、垫圈等。
• Polyurethane oligomer impact and shrinkage modifiers for thermoset polyesters
  申请人：OLIN CORPORATION

  公开号：EP0074746A1

  公开（公告）日：1983-03-23

  The polyurethane oligomer reaction product of a hydroxyl-terminated prepolymer with a dicarboxylic acid anhydride is incorporated into conventional thermosetting polyester resin formulations to impart improved impact properties and reduced shrinkage behaviour.

  在传统的热固性聚酯树脂配方中加入羟基封端预聚物与二羧酸酐的聚氨酯低聚物反应产物，可改善冲击性能并降低收缩性能。