1-phenyl-2-(2-pyridyl)-1,2-disodiumethane

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-phenyl-2-(2-pyridyl)-1,2-disodiumethane
• 英文别名: 1-phenyl-2-(2-pyridyl)-disodiumethane
• 化学式: C₁₃H₁₁NNa₂
• 分子量: 227.217
• InChiKey: MTKWZXLCWVTTAX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.49
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  1-phenyl-2-(2-pyridyl)-1,2-disodiumethane 、 1,2-二氯十二烷 以 四氢呋喃 为溶剂， 反应 1.0h， 生成 1-十二烯十二碳烯α-十二碳烯α-十二碳烯
  参考文献：
  名称：

  A new and highly effective organometallic approach to 1,2-dehalogenations and related reactions

  摘要：

  We investigated the reductive elimination of several functionalized and non-functionalized vic-dibromides with 1,2-diphenyl-, 1, 1,2,2-tetraphenyl- and l-phenyl-2-(2-pyridyl)-1,2-disodioethane. The reaction, involving some of the less expensive organic and inorganic reagents, proceeds under mild conditions, and is tolerant of a variety of functional groups. Extension of this procedure to similar 1,2-disubstituted compounds was also investigated. Reductive eliminations run on stereochernical probe compounds strongly suggest that this reaction proceeds via a "single electron" reductive elimination reaction pathway. (c) 2007 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.jorganchem.2007.05.039
• 作为试剂：
  描述：

  1-(1,2-二溴丙基)-4-甲氧基苯 在 1-phenyl-2-(2-pyridyl)-1,2-disodiumethane 作用下， 以 四氢呋喃 为溶剂， 反应 10.0h， 以90%的产率得到茴香烯
  参考文献：
  名称：

  Reducing properties of 1,2-diaryl-1,2-disodiumethanes

  摘要：

  1,2-Diphenyl- and 1-phenyl-2-(2-pyridyl)-1,2-disodiumethane efficiently dehalogenate vic-dibromoderivatives, affording the corresponding alkenes. The reaction proceeds rapidly, under mild conditions and is tolerant of a variety of functional groups (alcohol, carboxylic acid, ester and amide). This procedure was successfully extended to similar vic-disubstituted compounds. (c) 2005 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2005.12.054