dinitromethane sodium salt

• 分子结构分类: 有机化合物 - 有机1,3-偶极化合物 - 烯丙基型1,3-偶极有机化合物
• 英文名称: dinitromethane sodium salt
• 英文别名: dinitromethane; sodium salt
• 化学式: CHN₂NaO₄
• 分子量: 128.02
• InChiKey: SIKHXSAZIYZHDS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.72
• 重原子数：
  8
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  91.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  dinitromethane sodium salt 在 fluorine 、 sodium fluoride 作用下， 以53%的产率得到二氟-二硝基甲烷
  参考文献：
  名称：

  Solid-phase fluorination of salts of nitro compounds

  摘要：

  DOI：

  10.1007/bf00955979

文献信息

• Side-chain prototropic tautomerism of 4-hydroxyfuroxans in methylation reactions
  作者：Leonid L. Fershtat、Margarita A. Epishina、Igor V. Ovchinnikov、Marina I. Struchkova、Anna A. Romanova、Ivan V. Ananyev、Nina N. Makhova

  DOI：10.1016/j.tetlet.2016.11.023

  日期：2016.12

  A general and simple method for the preparation of under explored 3-aryl-4-hydroxyfuroxans by nucleophilic substitution of the nitro group in 3-aryl-4-nitrofuroxans using NaOH in H2O-THF has been developed. The methylation of 3-aryl-4-hydroxyfuroxans was studied with various methylating reagents (CH2N2, MeI, (MeO)2SO2) which showed for the first time that 3-aryl-4-hydroxyfuroxans are prone to side-chain

  已经开发了通过使用H 2 O-THF中的NaOH亲核取代3-芳基-4-硝基呋喃烷中的硝基来制备待探索的3-芳基-4-羟基呋喃烷的通用而简单的方法。用各种甲基化试剂（CH 2 N 2，MeI，（MeO）2 SO 2）研究了3-芳基-4-羟基呋喃恶烷的甲基化，这首次表明3-芳基-4-羟基呋喃恶烷倾向于侧-链质变互变异构。在温和条件下，合成了新型呋喃喃衍生物，N（5）-烷基化产物（3-芳基-5-甲基-1,2,5-恶二唑-4（2 H）-一2-氧化物）。与O的区域选择性形成-烷基化产物（3-芳基-4-甲氧基呋喃烷）。
• Regioselective synthesis of bifuroxanyl systems with the 3-nitrobifuroxanyl core via a one-pot acylation/nitrosation/cyclization cascade
  作者：Leonid L. Fershtat、Alexander A. Larin、Margarita A. Epishina、Alexander S. Kulikov、Igor V. Ovchinnikov、Ivan V. Ananyev、Nina N. Makhova

  DOI：10.1016/j.tetlet.2016.08.011

  日期：2016.9

  3-nitrobifuroxanyl core, based on a cascade of one-pot reactions comprising of the acylation of dinitromethane sodium salt with furoxanyl hydroxamic acid chlorides, nitrosation of the acylation product with NaNO2/AcOH/AcONa, and intramolecular cyclization of the nitrosation product to give the 3-nitrobifuroxanyl moiety, has been developed.

  基于一锅反应的级联反应，用于合成先前未知的包含3-硝基联呋喃基核心的联呋喃基系统的区域选择性方法，该反应包括二硝基甲烷钠盐与呋喃基异羟肟酸氯化物的酰化，酰化产物与NaNO 2 /的亚硝化已经开发了AcOH / AcONa，以及亚硝化产物的分子内环化以生成3-硝基联呋喃基基团部分。
• Gmelin Handbuch der Anorganischen Chemie, Gmelin Handbook: Fe: Org.Verb.A4, 5.1.4.6.2, page 193 - 202
  作者：

  DOI：——

  日期：——
• Tropylation and pyrylation of salts of aliphatic mono-, di-, and trinitro compounds
  作者：A. A. Gakh、A. S. Kiselev

  DOI：10.1007/bf00960417

  日期：1991.9

  We have studied the reactions of salts of nitroalkanes with tropylium and 2,6-diphenylpyrylium salts leading to products of C-tropylation and C-pyrylation of the corresponding anions. The only exception is the salt of cyanodinitromethane, which is not tropylated. Splitting off of a HNO2 molecule from the products of tropylation of nitroalkane anions to prepare nitroheptafulvenes was unsuccessful.
• gem-Dinitro compounds in organic synthesis. 2. Synthesis of 4-nitropyrazoles from dinitromethane and its derivatives
  作者：A. L. Laikhter、T. I. Cherkasova、V. V. Semenov

  DOI：10.1007/bf00959723

  日期：1991.12

  A series of 4-nitropyrazoles was synthesized from dinitromethane and other gemdinitro derivatives. New cyclization reactions of aliphatic azines with dinitromethane and an intramolecular cyclization of dinitroacetazines have been discovered, with which 4-nitropyrazoles substituted at the 3- and 5-positions of the pyrazole ring can be obtained in one stage.