(Z)-3-(2-methoxy-phenylamino)-1-phenyl-but-2-en-1-one

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (Z)-3-(2-methoxy-phenylamino)-1-phenyl-but-2-en-1-one
• 英文别名: (Z)-1-phenyl-3-(2-methoxyanilino)but-2-enone；(Z)-3-(2-Methoxyanilino)-1-phenylbut-2-en-1-one
• 化学式: C₁₇H₁₇NO₂
• 分子量: 267.327
• InChiKey: QPEJHLFJQICRNS-SEYXRHQNSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.3
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  38.3
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  邻甲氧基苯胺 、 1-苯基-1,3-丁二酮 在 ammonium cerium(IV) nitrate 作用下， 反应 1.67h， 以88%的产率得到(Z)-3-(2-methoxy-phenylamino)-1-phenyl-but-2-en-1-one
  参考文献：
  名称：

  一种用硝酸铈铵 (CAN) 烯胺化 1,3-二羰基化合物的有效方法

  摘要：

  已经描述了一种通过使用硝酸铈铵 (CAN) 作为催化剂来烯化 1,3-二羰基化合物的有效方法。在无溶剂条件下，在很短的反应时间内以优异的收率合成了多种 β-氨基-α,β-不饱和酮和酯。

  DOI：

  10.1002/jccs.200700127

文献信息

• Vanadium(IV) acetylacetonate catalyzed stereoselective synthesis of β-enaminoesters and β-enaminones
  作者：Rajibul A. Laskar、Naznin A. Begum、Mohammad Hedayetullah Mir、Shahzad Ali、Abu T. Khan

  DOI：10.1016/j.tetlet.2012.11.051

  日期：2013.1

  and stereoselective procedure has been described for the synthesis of a series of β-enaminoesters and β-enaminones by vanadium(IV) acetylacetonate [VO(acac)2] catalyzed reaction of β-ketoesters and 1,3-diketones with both aliphatic and aromatic amines. X-ray crystallographic studies of some representative compounds corroborate two types of structural geometry formed by inter-molecular as well as intra-molecular

  已经描述了一种有效的立体选择性方法，该方法可通过乙酰丙酮钒（IV）[VO（acac）2 ]催化β-酮酸酯和1,3-二酮与脂肪族化合物的合成来合成一系列β-烯胺酯和β-烯酮和芳香胺。一些代表性化合物的X射线晶体学研究证实了分子间和分子内氢键形成的两种类型的结构几何形状。
• A General and Efficient Method for the Preparation of β-Enamino Ketones and Esters Catalyzed by Indium Tribromide
  作者：Zhan-Hui Zhang、Liang Yin、Yong-Mei Wang

  DOI：10.1002/adsc.200505268

  日期：2006.1

  A variety of β-enamino ketones and esters have been synthesized in high to exellent yields by reacting β-dicarbonyl compounds with amines in the presence of a catalytic amount of indium tribromide. The reaction proceeds smoothly at room temperature in a short reaction time under solvent-free conditions.

  在催化量的三溴化铟存在下，通过使β-二羰基化合物与胺反应，可以高产率地合成出多种β-烯胺酮和酯。在无溶剂条件下，反应在室温下以短的反应时间平稳地进行。
• ORGANIC COMPOUNDS CONTAINING HETEROATOMS AND THEIR USE IN ZIEGLER-NATTA CATALYST WITH SINGLE ACTIVATION CENTER
  申请人：SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES

  公开号：EP2039677A1

  公开（公告）日：2009-03-25

  Organic compounds containing heteroatoms and their use in preparing Ziegler-Natta (Z-N) catalyst with single activation center. The Z-N olefin polymerization catalyst is prepared by adding organic or inorganic solid carrier or compound of them which is pre-activated by heating or pre-treated chemically, organic compound containing heteroatoms and metallic compound into magnesium compound/tetrahydrofuran solution. The Z-N olefin polymerization catalyst prepared in the present invention is fluidizable powder and can prepare ethene homopolymer and copolymer of controllable construction with high catalytic activity, during homo-polymerization and combined polymerization with alpha-olefin of C3-C8 under action of catalyst promoter such as alkyl aluminium, alkyl aluminoxane, and so on.

  含有杂原子的有机化合物及其在制备具有单活化中心的齐格勒-纳塔（Z-N）催化剂中的应用。Z-N 烯烃聚合催化剂的制备方法是在镁化合物/四氢呋喃溶液中加入经加热预活化或化学预处理的有机或无机固体载体或它们的化合物、含杂原子的有机化合物和金属化合物。本发明制备的 Z-N 烯烃聚合催化剂为可流动粉末，在烷基铝、烷基铝氧烷等催化剂促进剂的作用下，与 C3-C8 α-烯烃进行均聚和联合聚合时，可制备结构可控、催化活性高的乙烯均聚物和共聚物。
• Organic compounds containing heteroatoms and their use in ziegler-natta catalyst with single activation center
  申请人：SHANGHAI INSTITUTE OF ORGANIC CHEMISTRY, CHINESE ACADEMY OF SCIENCES

  公开号：EP2039677B1

  公开（公告）日：2014-04-23
• CLASS OF ORGANIC COMPOUNDS CONTAINING HETEROATOM AND ITS APPLICATIONS IN PREPARING SINGLE-SITE ZIEGLER-NATTA CATALYST
  申请人：TANG Yong

  公开号：US20090137383A1

  公开（公告）日：2009-05-28

  Organic compounds containing heteroatoms and their use in preparing Ziegler-Natta (Ziegler-Natta) catalyst with single activation center. The Ziegler-Natta olefin polymerization catalyst is preparing by adding organic or inorganic solid carrier or compound of them which is pre-activated by heating or pre-treated chemically, organic compound containing heteroatoms and metallic compound into magnesium compound/tetrahydrofuran solution. The Ziegler-Natta olefin polymerization catalyst prepared in the present invention is fluidizable powder and can prepare ethene homopolymer and copolymer of controllable construction with high catalytic activity, during homo-polymerization and combined polymerization with alpha-olefin of C 3 ˜C 18 under action of catalyst promoter such as alkyl aluminum, alkyl aluminoxane, and so on.