1-(2,3-dimethylphenyl)-2,5-dimethyl-1H-pyrrole

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 1-(2,3-dimethylphenyl)-2,5-dimethyl-1H-pyrrole
• 英文别名: 1-(2,3-dimethyl-phenyl)-2,5-dimethyl-pyrrole；1-(2,3-Dimethyl-phenyl)-2,5-dimethyl-pyrrol；1-(2,3-Dimethylphenyl)-2,5-dimethylpyrrole
• 化学式: C₁₄H₁₇N
• mdl: MFCD03576687
• 分子量: 199.296
• InChiKey: ZYAOBNNKTUTUJJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.9
• 重原子数：
  15
• 可旋转键数：
  1
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.285
• 拓扑面积：
  4.9
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  1-(2,3-dimethylphenyl)-2,5-dimethyl-1H-pyrrole 、 丙酰氯 在 二硫化碳 、 三氯化铝 作用下， 生成 1-[1-(2,3-dimethyl-phenyl)-2,5-dimethyl-pyrrol-3-yl]-propan-1-one
  参考文献：
  名称：

  609.致癌氮化合物的化学作用。第三部分 多取代的吡咯和吲哚是潜在的致癌物

  摘要：

  DOI：

  10.1039/jr9490002882
• 作为产物：
  描述：

  5-已烯-2-酮 、 2,3-二甲基苯胺 在 palladium(II) trifluoroacetate 、 氧气 作用下， 以 甲苯 为溶剂， 以75%的产率得到1-(2,3-dimethylphenyl)-2,5-dimethyl-1H-pyrrole
  参考文献：
  名称：

  通过Pd（OCOCF 3）2催化5-己烯-2-酮与伯胺的有效合成取代的吡咯

  摘要：

  已经开发了一种有效且简便的Pd（OCOCF 3）2催化的一锅级联方案，用于合成多个取代的吡咯，产率高至优异。与报道的从2-链烯基-1,3-羰基化合物开始的方法不同，该方法利用了反应性较低的5-己烯-2-酮，该方法具有很大的潜力作为对当前开发方法的补充。

  DOI：

  10.1016/j.tetlet.2016.10.029

文献信息

• ORGANIC ELECTROLUMINESCENCE ELEMENT, LIGHTING DEVICE AND DISPLAY DEVICE
  申请人：Katakura Rie

  公开号：US20100045171A1

  公开（公告）日：2010-02-25

  Disclosed is an organic electroluminescent device having high external quantum efficiency and long emission life. Also disclosed are an illuminating device and a display, each comprising such an organic electroluminescent device. The organic electroluminescent device is characterized by comprising at least an anode and a cathode on a supporting substrate, while having at least one light-emitting layer between the anode and the cathode. The organic electroluminescent device is also characterized by containing a polymer which at least partially contains a compound A having a partial structure represented by the general formula (a) below and a reactive group, and is obtained by polymerizing the compound A through the reactive group. (In the formula, Ar1 and Ar2 respectively represent an aromatic ring.)
• ORGANIC ELECTROLUMINESCENCE ELEMENT, NEW COMPOUND FOR THE SAME, DISPLAY DEVICE AND LIGHTING DEVICE USING THE SAME
  申请人：KATAKURA Rie

  公开号：US20110006670A1

  公开（公告）日：2011-01-13

  Disclosed is an organic electroluminescence element comprising an anode, a cathode and a plurality of organic compound layers between the anode and the cathode, provided that one of the organic compound layers is a light emitting layer containing a phosphorescence emitting compound, wherein at least one of the organic compound layers contains a compound represented by Formula (1), wherein, X represents O or S; Y 1 to Y 3 each represents a hydrogen atom, a substituent or a group represented by Formula (A) disclosed in the specification, provided that at least two of Y 1 to Y 3 are groups represented by Formula (A), not all of Y 1 to Y 3 are the same group, and at least one of the groups represented by Formula (A) has Ar of a carbazolyl group, or an azacarbazolyl group containing 2 to 5 nitrogen atoms.
• US8852757B2
  申请人：——

  公开号：US8852757B2

  公开（公告）日：2014-10-07
• US9617255B2
  申请人：——

  公开号：US9617255B2

  公开（公告）日：2017-04-11
• Efficient synthesis of substituted pyrroles through Pd(OCOCF3)2-catalyzed reaction of 5-hexen-2-one with primary amines
  作者：Xi Chen、Meng Yang、Min Zhou

  DOI：10.1016/j.tetlet.2016.10.029

  日期：2016.11

  An efficient and facile Pd(OCOCF3)2-catalyzed one-pot cascade protocol has been developed for the synthesis of multiple substituted pyrroles in good to excellent yields. Unlike the reported method starting from the 2-alkenal-1,3-carbonyl compounds, the process utilizes the less reactive 5-hexen-2-one and the method has great potential as a complement to the current developed methods.

  已经开发了一种有效且简便的Pd（OCOCF 3）2催化的一锅级联方案，用于合成多个取代的吡咯，产率高至优异。与报道的从2-链烯基-1,3-羰基化合物开始的方法不同，该方法利用了反应性较低的5-己烯-2-酮，该方法具有很大的潜力作为对当前开发方法的补充。