N-(2,5-dimethylphenyl)-m-toluidine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(2,5-dimethylphenyl)-m-toluidine
• 英文别名: 2,5-dimethyl-N-(3-methylphenyl)aniline
• 化学式: C₁₅H₁₇N
• 分子量: 211.307
• InChiKey: GBNSXDYOJRYFDN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  16
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  12
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  N-(2,5-dimethylphenyl)-m-toluidine 在 copper diacetate 、 palladium diacetate 、 N,N-二甲基甲酰胺 作用下， 反应 4.0h， 以62%的产率得到1,4,7-trimethyl-9H-carbazole
  参考文献：
  名称：

  二芳基胺和甲基咔唑的合成及生物碱玫瑰树碱和橄榄碱的正式全合成

  摘要：

  描述了一种用于合成 1-甲基和 1,4-二甲基 3-甲酰基咔唑的通用且有效的方法。微波促进 4-恶唑啉-2-酮的一锅级联反应得到甲基化二芳基胺，将其环化成一系列咔唑，包括天然存在的吡啶并[4,3- b ]咔唑生物碱玫瑰树碱的正式全合成和橄榄素。

  DOI：

  10.1002/ejoc.202200364
• 作为产物：
  描述：

  异氰酸间甲苯酯 以 neat (no solvent) 为溶剂， 反应 9.0h， 生成 N-(2,5-dimethylphenyl)-m-toluidine
  参考文献：
  名称：

  二芳基胺和甲基咔唑的合成及生物碱玫瑰树碱和橄榄碱的正式全合成

  摘要：

  描述了一种用于合成 1-甲基和 1,4-二甲基 3-甲酰基咔唑的通用且有效的方法。微波促进 4-恶唑啉-2-酮的一锅级联反应得到甲基化二芳基胺，将其环化成一系列咔唑，包括天然存在的吡啶并[4,3- b ]咔唑生物碱玫瑰树碱的正式全合成和橄榄素。

  DOI：

  10.1002/ejoc.202200364

文献信息

• Use of Polymer-Supported Dialkylphosphinobiphenyl Ligands for Palladium-Catalyzed Amination and Suzuki Reactions
  作者：Cynthia A. Parrish、Stephen L. Buchwald

  DOI：10.1021/jo010025w

  日期：2001.6.1

  The preparations of polymer-supported dialkylphosphinobiphenyl ligands (3) are reported. A palladium catalyst based on ligand 3a is active for amination and Suzuki reactions using unactivated aryl iodides, bromides, or chlorides. Filtration of the catalyst from the reaction mixture allows for simplified product isolation via an aqueous workup. The resin-bound catalyst can be recycled without additional

  报道了聚合物负载的二烷基膦基联苯配体（3）的制备。基于配体3a的钯催化剂对于使用未活化的芳基碘化物，溴化物或氯化物的胺化和Suzuki反应具有活性。从反应混合物中过滤催化剂可以通过水后处理简化产物分离。树脂结合的催化剂可以在胺化反应和Suzuki反应中无需额外的钯即可循环使用。
• COMPOSITION FOR ANODE BUFFER LAYERS, HIGH-MOLECULAR COMPOUND FOR ANODE BUFFER LAYERS, ORGANIC ELECTROLUMINESCENT ELEMENT, PROCESS FOR PRODUCTION OF SAME, AND USE THEREOF
  申请人：Showa Denko K.K.

  公开号：EP2495287A1

  公开（公告）日：2012-09-05

  There is provided a material for an anode buffer layer which permits the use of an organic solvent as a solvent of an anode buffer layer-forming solution, and is capable of forming an anode buffer layer that does not dissolve even when coated with a luminescent layer-forming material solution containing an organic solvent as a solvent, and which is capable of producing an organic EL element having high electrical power efficiency and long life. The composition for an anode buffer layer includes an electron-accepting compound and a high-molecular weight compound having a structural unit represented by the following formula (1) or the following formula (2) and having a weight average molecular weight of 20,000 to 1,000,000 as measured by GPC: wherein in each of the formulae (1) and (2), plural Ras are each a hydrogen atom or an alkyl group, with at least one Ra being the alkyl group, plural Rbs are each a hydrogen atom or an alkyl group, plural Rcs are each a hydrogen atom, an alkyl group or the like, X is a single bond or the like, Y is a structure derived from a vinyl group and the like, and p is 0, 1 or 2.

  本发明提供了一种用于阳极缓冲层的材料，该材料允许使用有机溶剂作为阳极缓冲层形成溶液的溶剂，并且能够形成即使涂覆了含有有机溶剂作为溶剂的发光层形成材料溶液也不会溶解的阳极缓冲层，并且能够生产出具有高电功率效率和长寿命的有机电致发光元件。 用于阳极缓冲层的组合物包括一种电子接受化合物和一种高分子量化合物，其结构单元由下式（1）或下式（2）表示，经 GPC 测定，其重量平均分子量为 20,000 至 1,000,000： 其中，在式（1）和式（2）中，多个 Ras 各为氢原子或烷基，其中至少一个 Ra 为烷基；多个 Rbs 各为氢原子或烷基；多个 Rcs 各为氢原子、烷基或类似物；X 为单键或类似物；Y 为乙烯基等衍生结构；p 为 0、1 或 2。
• COMPOSITION FOR ANODE BUFFER LAYER, HIGH-MOLECULAR WEIGHT COMPOUND FOR ANODE BUFFER LAYER, ORGANIC ELECTROLUMINESCENCE ELEMENT, AND PRODUCTION PROCESS AND USES OF THE SAME
  申请人：Osako Haruka

  公开号：US20120217491A1

  公开（公告）日：2012-08-30

  There is provided a material for an anode buffer layer which permits the use of an organic solvent as a solvent of an anode buffer layer-forming solution, and is capable of forming an anode buffer layer that does not dissolve even when coated with a luminescent layer-forming material solution containing an organic solvent as a solvent, and which is capable of producing an organic EL element having high electrical power efficiency and long life. The composition for an anode buffer layer includes an electron-accepting compound and a high-molecular weight compound having a structural unit represented by the following formula (1) or the following formula (2) and having a weight average molecular weight of 20,000 to 1,000,000 as measured by GPC: wherein in each of the formulae (1) and (2), plural R a s are each a hydrogen atom or an alkyl group, with at least one R a being the alkyl group, plural R b s are each a hydrogen atom or an alkyl group, plural R c S are each a hydrogen atom, an alkyl group or the like, X is a single bond or the like, Y is a structure derived from a vinyl group and the like, and p is 0, 1 or 2.
• US9644048B2
  申请人：——

  公开号：US9644048B2

  公开（公告）日：2017-05-09
• Synthesis of Diarylamines and Methylcarbazoles and Formal Total Synthesis of Alkaloids Ellipticine and Olivacine
  作者：Edson Barrera、R. Israel Hernández‐Benitez、Carlos A. González‐González、Carlos H. Escalante、Aydeé Fuentes‐Benítes、Carlos González‐Romero、Elvia Becerra‐Martínez、Francisco Delgado、Joaquín Tamariz

  DOI：10.1002/ejoc.202200364

  日期：2022.6.27

  A versatile and efficient methodology for the synthesis of 1-methyl and 1,4-dimethyl 3-formylcarbazoles is described. Microwave-promoted one-pot cascade reactions of 4-oxazolin-2-ones afforded methylated diarylamines, which were cyclized into a series of carbazoles, including the formal total synthesis of the naturally occurring pyrido[4,3-b]carbazole alkaloids ellipticine and olivacine.

  描述了一种用于合成 1-甲基和 1,4-二甲基 3-甲酰基咔唑的通用且有效的方法。微波促进 4-恶唑啉-2-酮的一锅级联反应得到甲基化二芳基胺，将其环化成一系列咔唑，包括天然存在的吡啶并[4,3- b ]咔唑生物碱玫瑰树碱的正式全合成和橄榄素。