3-chloroprop-2-enylglycidyl ether

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 环氧化物
• 英文名称: 3-chloroprop-2-enylglycidyl ether
• 英文别名: 3-Chloroprop-2-enylglycidyl ether；2-(3-chloroprop-2-enoxymethyl)oxirane
• 化学式: C₆H₉ClO₂
• 分子量: 148.589
• InChiKey: NIHUGASCAJHXJK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.7
• 重原子数：
  9
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  21.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  2-乙基己醇 、 环氧氯丙烷 在 四丁基溴化铵 、 sodium hydroxide 作用下， 反应 12.5h， 生成 辛基缩水甘油醚 、 1,3-di(2-ethylhexyloxy)-2-propylglycidyl ether 、 3-chloroprop-2-enylglycidyl ether
  参考文献：
  名称：

  에틸헥실글리세린의 제조방법

  摘要：

  本发明涉及一种制备2-乙基己基环氧乙醚（2-Ethylhexylglycidyl ether）的方法，包括以下步骤：（A）搅拌2-乙基己基环氧乙醚、水、有机溶剂和催化剂；（B）在搅拌后，在80~120℃下反应15~25小时合成乙基己基甘油；（C）在合成后加入乙酸乙酯（Ethylacetate）；（D）在步骤（C）中，去除分离的水层，提取有机层；（E）蒸馏提取有机层以获得乙基己基甘油。

  公开号：

  KR101528751B1

文献信息

• Improvement of the phase-transfer catalysis method for synthesis of glycidyl ether
  作者：Ho-Cheol Kang、Byung Min Lee、Jungho Yoon、Minjoong Yoon

  DOI：10.1007/s11746-001-0279-y

  日期：2001.4

  AbstractA convenient procedure for the synthesis of aliphatic alkylglycidyl ether has been studied. It has been found that the improved preparation of the alkylglycidyl ether can be achieved by using fatty alcohol such as octanol and octadecanol with epichlorohydrin in the presence of phase‐transfer catalyst (PTC) such as 1‐alkyloxypropan‐2‐ol‐3‐trimethyl ammonium methylsulfate, 1‐alkyloxypropan‐2‐ol‐3‐methyldiethanolammonium methylsulfate, alkyloxy‐2‐hydroxypropyldimethylamine and alkyloxy‐2‐hydroxypropyldiethanolamine, tetrabutylammonium bromide, etc. without water and other organic solvents. This method, carried out in solid phase/organic phase (reactants and product themselves), has the following merits: (i) producing the solid by‐products such as sodium chloride and sodium hydroxide which are easily removed by simple filtration, (ii) saving the amount of reactants used such as sodium chloride and phase‐transfer catalyst, and (iii) increasing the yields of glycidyl ethers. The yields of octylglycidyl ether and octadecylglycidyl ether are 92.0 and 91.7%, respectively. The amount of sodium hydroxide used can be saved by from 1.5 to 0.7 molar ratio with respect to octanol in comparison with those in the conventional method using PTC.
• 에틸헥실글리세린의 제조방법
  申请人：YEO MYUNG BIOCHEM Co., Ltd. 여명바이오켐 주식회사(120140615223) Corp. No ▼ 150111-0160890BRN ▼317-81-29414

  公开号：KR101528751B1

  公开（公告）日：2015-06-16

  본 발명은 2-에틸헥실글리시딜 에테르(2-Ethylhexylglycidyl ether), 물, 유기 용매 및 촉매를 교반하는 단계 (A); 상기 교반 후, 80~120℃에서 15~25시간 동안 반응시켜 에틸헥실글리세린을 합성하는 단계 (B); 상기 합성 후, 에틸아세테이트(Ethylacetate)를 가하는 단계 (C); 상기 단계 (C)에서, 분리된 물층을 제거한 후, 유기층을 수세하는 단계 (D); 및 상기 수세된 유기층을 증류하여 에틸헥실글리세린을 수득하는 단계 (E);를 포함하는 것을 특징으로 하는 에틸헥실글리세린의 제조방법을 제공한다.

  本发明涉及一种制备2-乙基己基环氧乙醚（2-Ethylhexylglycidyl ether）的方法，包括以下步骤：（A）搅拌2-乙基己基环氧乙醚、水、有机溶剂和催化剂；（B）在搅拌后，在80~120℃下反应15~25小时合成乙基己基甘油；（C）在合成后加入乙酸乙酯（Ethylacetate）；（D）在步骤（C）中，去除分离的水层，提取有机层；（E）蒸馏提取有机层以获得乙基己基甘油。