十二(烷)酸十四(烷)酯 | 22412-97-1

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 十二(烷)酸十四(烷)酯
• 中文别名: 月桂酸十四烷酯
• 英文名称: dodecanoic acid tetradecyl ester
• 英文别名: myristyl dodecanoate；n-tetradecyl laurate；tetradecyl laurate；myristyl laurate；n-Dodecansaeure-n-tetradecylester；Dodecansaeure-tetradecylester；tetradecyl dodecanoate
• CAS: 22412-97-1
• 化学式: C₂₆H₅₂O₂
• 分子量: 396.698
• InChiKey: FNMPODAQERUMDD-UHFFFAOYSA-N

物化性质

• 沸点：
  407℃[at 101 325 Pa]
• 密度：
  0.85[at 20℃]
• LogP：
  11.7 at 25℃
• 物理描述：
  OtherSolid
• 保留指数：
  2752.66;2750

计算性质

• 辛醇/水分配系数(LogP)：
  11.9
• 重原子数：
  28
• 可旋转键数：
  24
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.961
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 海关编码：
  2915900090

制备方法与用途

月桂酸肉豆蔻酯是一种生物化学试剂，可用作生物材料或有机化合物，广泛应用于生命科学研究。

反应信息

• 作为产物：
  描述：

  甘油三酯 、 十四醇 在 十二烷基苯磺酸 作用下， 以 水 为溶剂， 反应 168.0h， 以87%的产率得到十二(烷)酸十四(烷)酯
  参考文献：
  名称：

  Dehydration Reactions in Water. Brønsted Acid−Surfactant-Combined Catalyst for Ester, Ether, Thioether, and Dithioacetal Formation in Water

  摘要：

  Dehydration reactions in water have been realized by a surfactant-type catalyst, dodecylbenzenesulfonic acid (DBSA). These reactions include dehydrative esterification, etherification, thioetherification, and dithioacetalization. In these reactions, DBSA and substrates form emulsion droplets whose interior is hydrophobic enough to exclude water molecules generated during the reactions. Detailed studies on the esterification revealed that the yields of esters were affected by temperature, amounts of DBSA used, and the substrates. Esters were obtained in high yields for highly hydrophobic substrates. On the basis of the difference in hydrophobicity of the substrates, unique selective esterification and etherification in water were attained. Furthermore, chemospecific, three-component reactions under DBSA-catalyzed conditions were also found to proceed smoothly. This work not only may lead to environmentally benign systems but also will provide a new aspect of organic chemistry in water.

  DOI：

  10.1021/ja026241j

文献信息

• Allantoin-containing preparations for administration as gels and aerosols
  申请人：Alwyn Company, Inc.

  公开号：US20030147968A1

  公开（公告）日：2003-08-07

  Allantoin-containing preparations are prepared in a form suitable for administration as gels and aerosols. In one embodiment of the aerosol formulation, an allantoin-containing composition comprises: (1) water; (2) allantoin in a therapeutically effective quantity; (3) an anionic ethoxylated surfactant; (4) lanolin oil; and (5) cod liver oil. The composition has a viscosity and surface tension in a range that allows the composition to be administered to the skin of a user as an aerosol by a mechanical spray pump. In another aspect of this invention, the allantoin-containing preparations are prepared in a form suitable for administration as gels. The compositions can be substantially anhydrous or can contain water. In one embodiment of the gel formation, an allantoin-containing composition comprises: (1) allantoin in a therapeutically effective quantity; (2) a complex comprising mineral oil and at least one hydrogenated alkylene copolymer; (3) lanolin oil; and (4) cod liver oil. The compositions can comprise other ingredients. Compositions according to the present invention are suitable for the treatment of a number of skin conditions or diseases characterized by ulceration, inflammation, or blistering of the skin, such as epidermolysis bullosa.

  含有尿囊素的制剂以适合作为凝胶和气雾剂的形式制备。在气雾剂配方的一个实施例中，含有尿囊素的组合物包括：（1）水；（2）疗效有效量的尿囊素；（3）阴离子乙氧基化表面活性剂；（4）羊毛脂油；和（5）鱼肝油。该组合物具有粘度和表面张力范围，使得通过机械喷雾泵将组合物作为气雾施用到用户皮肤上。在这项发明的另一个方面，含有尿囊素的制剂以适合作为凝胶的形式制备。这些组合物可以是几乎无水的，也可以含水。在凝胶形成的一个实施例中，含有尿囊素的组合物包括：（1）疗效有效量的尿囊素；（2）包括矿物油和至少一种氢化烷烯共聚物的复合物；（3）羊毛脂油；和（4）鱼肝油。这些组合物可以包含其他成分。根据本发明的组合物适用于治疗一系列皮肤状况或疾病，其特征是皮肤溃疡、炎症或水疱，如表皮溶解性水疱症。
• Long chain diol diesters as low calorie fat mimetics
  申请人：NABISCO, INC.

  公开号：EP0405873A1

  公开（公告）日：1991-01-02

  Long chain diol diesters, notably 11- to 30- carbon aliphatic chains having two vicinal fatty acid esters or dicarboxylate-extended fatty acid esters, or two fatty acid esters or dicarboxylate-extended fatty acid esters separated by one or two methylene groups, attached to one end of the chain, are edible, preferably partially digestible, fat replacements for foods and pharmaceuticals.

  长链二醇双酯，尤其是具有两个邻近脂肪酸酯或二羧酸扩展脂肪酸酯的11-至30-碳链，或者具有两个脂肪酸酯或二羧酸扩展脂肪酸酯，其之间隔着一个或两个亚甲基基团，附着在链的一端，是食品和药品的可食用、部分可消化的脂肪替代品。
• Magnetic disc
  申请人：Hitachi Maxell Ltd.

  公开号：EP0206244A2

  公开（公告）日：1986-12-30

  A magnetic disc comprising a non-magnetic supporting substrate and a magnetic layer consisting of a magnetic coating which is formed on at least one surface of the substrate and comprises ferromagnetic powder, a binder, an aliphatic acid ester having a melting point not higher than 10°C and an aliphatic acid ester having a melting point of 15 to 60°C, the magnetic coating of which has improved lubricity and durability.

  一种磁性圆盘，包括非磁性支撑基板和磁性涂层组成的磁性层，磁性涂层至少形成在基板的一个表面上，由铁磁性粉末、粘结剂、熔点不高于 10°C 的脂肪族酸酯和熔点为 15 至 60°C 的脂肪族酸酯组成，其磁性涂层具有更好的润滑性和耐用性。
• Thermochromic microencapsulated pigments
  申请人：THE PILOT INK CO., LTD.

  公开号：EP1084860A2

  公开（公告）日：2001-03-21

  Disclosed is a thermochromic microencapsulated pigment which comprises as four essential components (a) an electron-donating chromatic organic compound, (b) an electron-accepting compound, (c) a reaction medium determining the temperatures at which the color reactions of component (a) with component (b) take place, and (d) a color change temperature regulator, the color change temperature regulator (d) comprising one or more compounds selected from the group consisting of esters, alcohols, ketones, acid amides, hydrocarbons, and fatty acids and having a melting point Y (°C) satisfying the relationship (X+30)°C≤Y≤200°C, wherein X (°C) is the melting point of component (c), and the four essential components being microencapsulated.

  本发明公开了一种热致变色微胶囊颜料，它由四种基本成分组成：(a) 一种电子供色有机化合物；(b) 一种电子受色化合物；(c) 一种决定成分(a)与成分(b)发生颜色反应的温度的反应介质；(d) 一种变色温度调节剂、变色温度调节剂(d)包括一种或多种从酯、醇、酮、酸酰胺、烃和脂肪酸组成的组中选出的化合物，其熔点 Y(℃)满足(X+30)℃≤Y≤200℃的关系，其中 X(℃)是组分(c)的熔点，四种基本组分被微胶囊化。
• Color changing candle
  申请人：Dragoco Gerberding & Co Aktiengesellschaft

  公开号：EP1090977A2

  公开（公告）日：2001-04-11

  A candle having a selectively and reversibly variable color pattern. In one embodiment, the candle comprises a solid transparent gel with a thermochromic or photochromic pigment dispersed evenly throughout. The candle main body changes from a first color to a second color, or from colored to transparent, or from transparent to colored, in response to heat or light from the candle flame, and reverts to the original color or absence of color upon extinguishing the flame. The candle comprises (a) a solid combustible matrix, and (b) a reversible thermochromic or photochromic composition blended into said solid combustible matrix.

  一种具有可选择、可逆变色图案的蜡烛。在一个实施方案中，蜡烛由固体透明凝胶组成，凝胶中均匀地分散着热致变色或光致变色颜料。蜡烛主体在烛焰的热量或光线作用下，从第一种颜色变为第二种颜色，或从有色变为透明，或从透明变为有色，熄灭火焰后又恢复到原来的颜色或无色。蜡烛包括 (a) 固体可燃基体，和 (b) 混入所述固体可燃基体的可逆热致变色或光致变色组合物。