pentafluorophenyl pyridin-2-sulfonate | 1199262-21-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: pentafluorophenyl pyridin-2-sulfonate
• 英文别名: Pentafluorophenyl pyridine-2-sulfonate；(2,3,4,5,6-pentafluorophenyl) pyridine-2-sulfonate
• CAS: 1199262-21-9
• 化学式: C₁₁H₄F₅NO₃S
• mdl: MFCD22391988
• 分子量: 325.216
• InChiKey: HUNMTSONVAJCQW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  64.6
• 氢给体数：
  0
• 氢受体数：
  9

反应信息

• 作为反应物：
  描述：

  pentafluorophenyl pyridin-2-sulfonate 、 苄胺 在 N,N-二异丙基乙胺 作用下， 以 乙腈 为溶剂， 以91%的产率得到N-benzylpyridine-2-sulfonamide
  参考文献：
  名称：

  Heterocyclic pentafluorophenyl sulfonate esters as shelf stable alternatives to sulfonyl chlorides

  摘要：

  Heterocyclic pentafluorophenyl sulfonate esters are shelf stable alternatives to the often less stable sulfonyl chlorides. They are easily prepared from thiols and react readily with primary and secondary amines to produce sulfonamides in high yields. (c) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.09.015
• 作为产物：
  描述：

  吡啶-2-磺酰氯 、 五氟苯酚 在 三乙胺 作用下， 以 二氯甲烷 为溶剂， 以7.41 g的产率得到pentafluorophenyl pyridin-2-sulfonate
  参考文献：
  名称：

  Heterocyclic pentafluorophenyl sulfonate esters as shelf stable alternatives to sulfonyl chlorides

  摘要：

  Heterocyclic pentafluorophenyl sulfonate esters are shelf stable alternatives to the often less stable sulfonyl chlorides. They are easily prepared from thiols and react readily with primary and secondary amines to produce sulfonamides in high yields. (c) 2009 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tet.2009.09.015

文献信息

• Heterocyclic pentafluorophenyl sulfonate esters as shelf stable alternatives to sulfonyl chlorides
  作者：Jan Bornholdt、Karianne Wilhemsen Fjære、Jakob Felding、Jesper Langgaard Kristensen

  DOI：10.1016/j.tet.2009.09.015

  日期：2009.11

  Heterocyclic pentafluorophenyl sulfonate esters are shelf stable alternatives to the often less stable sulfonyl chlorides. They are easily prepared from thiols and react readily with primary and secondary amines to produce sulfonamides in high yields. (c) 2009 Elsevier Ltd. All rights reserved.