十四烷基2-甲基庚烷酸酯 | 94088-84-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: 十四烷基2-甲基庚烷酸酯
• 英文名称: cetyl isooctanoate
• 英文别名: palmityl isooctylate；cetyl isooctanate；Hexadecyl 6-methylheptanoate
• CAS: 94088-84-3；72585-97-8
• 化学式: C₂₄H₄₈O₂
• 分子量: 368.644
• InChiKey: OIKBVOIOVNEVJR-UHFFFAOYSA-N

物化性质

• 保留指数：
  2460

计算性质

• 辛醇/水分配系数(LogP)：
  10.6
• 重原子数：
  26
• 可旋转键数：
  21
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  异辛酰氯 、 1-十六烷醇 在 吡啶 作用下， 以 丙酮 为溶剂， 反应 1.0h， 以80%的产率得到十四烷基2-甲基庚烷酸酯
  参考文献：
  名称：

  一种低极性油脂的制备方法

  摘要：

  本发明涉及精细化工产品领域，具体提供了一种低极性油脂的制备方法，该方法包括：在溶剂和缚酸剂存在下，将酰氯和脂肪醇进行接触反应，分离得到产品油脂。本发明的合成方法是用脂肪醇和酰氯发生亲核取代反应，该反应不存在逆反应(副产物是盐酸)，反应产率比一般酯化反应高，且工艺简单，反应条件温和，最终产率可高达80％，本发明的方法可制备出无色、无味、易于储存，稳定性好的产品。

  公开号：

  CN108003021B

文献信息

• MELANIN PRODUCTION INHIBITOR
  申请人：Yokoyama Kouji

  公开号：US20110243865A1

  公开（公告）日：2011-10-06

  Disclosed is a melanin production inhibitor which has an excellent inhibitory activity on the production of melanin and is highly safe. The melanin production inhibitor comprises a compound represented by general formula (1) (excluding clotrimazole), and/or a pharmacologically acceptable salt thereof. In the formula, A1, A2 and A3 are independently selected from a hydrogen atom, an aryl group which may have a substituent, and an aromatic heterocyclic group which may have a substituent, wherein at least one of A1, A2 and A3 is selected from the aryl group and the aromatic heterocyclic group, the total number of carbon atoms contained in A1, A2 and A3 is 6 to 50 and, when at least two of A1, A2 and A3 represent the aryl groups or the aromatic heterocyclic groups, the adjacent two aryl or aromatic heterocyclic groups may be bound to each other via an alkyl chain or an alkenyl chain to form a ring; m represents an integer of 0 to 2; X represents a hetero atom, a hydrogen atom, or a carbon atom; R1 and R2 are independently selected from a hydrogen atom and an oxo group, wherein when one of R1 and R2 is an oxo group, the other is not present; and R3 is selected from a hydrogen atom, and a C 1-8 hydrocarbon group in which one or some of hydrogen atoms or carbon atoms may be substituted by a hetero atom or hetero atoms, wherein the number of R3's present in the compound corresponds to the number of X's and, when two or more R3's are present, the R3's are independently present and the adjacent two R3's may be bound to each other to form, together with X, a ring, and the terminal of R3 may be bound to a carbon atom to which A1, A2 and A3 are bound, thereby forming a ring.

  披露了一种黑色素生产抑制剂，它对黑色素的生产具有出色的抑制活性且高度安全。该黑色素生产抑制剂包括由通用公式（1）表示的化合物（不包括克霉唑）和/或其药理上可接受的盐。在公式中，A1、A2和A3独立地选自氢原子、可能带有取代基的芳基团和可能带有取代基的芳香杂环团，其中至少A1、A2和A3之一选自芳基团和芳香杂环团，A1、A2和A3中包含的碳原子总数为6至50，并且当至少两个A1、A2和A3表示芳基团或芳香杂环团时，相邻的两个芳基或芳香杂环团可以通过烷基链或烯基链相互连接形成环；m代表0至2的整数；X代表异原子、氢原子或碳原子；R1和R2独立地选自氢原子和氧代基，其中当R1和R2之一是氧代基时，另一个不出现；R3选自氢原子和C 1-8 碳氢化合物组，其中一些或所有的氢原子或碳原子可能被异原子或异原子取代，其中化合物中存在的R3的数量对应于X的数量，并且当存在两个或更多R3时，R3独立地存在，并且相邻的两个R3可以相互连接以与X一起形成环，并且R3的末端可以与A1、A2和A3连接的碳原子结合，从而形成环。
• SUBSTITUTED DIHYDROPYRROLOPYRAZOLE DERIVATIVE
  申请人：UBE INDUSTRIES, LTD.

  公开号：US20180186818A1

  公开（公告）日：2018-07-05

  The present invention provides a compound represented by the general formula (Ia) or a pharmacologically acceptable salt thereof. In the general formula (Ia), two R moieties each independently represent a C 1-3 alkyl group or the like; and R 1 , R 2 and R 3 each independently represent an optionally substituted linear or branched C 1-4 alkyl group.

  本发明提供了一种由通用公式（Ia）表示的化合物或其药理可接受的盐。在通用公式（Ia）中，两个R基团各自独立地代表一个C1-3烷基团或类似物；而R1、R2和R3各自独立地代表一个可选地取代的线性或支链的C1-4烷基团。
• SUNSCREEN COSMETICS
  申请人：SHISEIDO COMPANY, LTD.

  公开号：EP1977730A1

  公开（公告）日：2008-10-08

  The present invention is a sunscreen cosmetic comprising 4-(1,1-dimethylethyl)-4'-methoxydibenzoylmethane, a benzotriazole derivative represented by the following general formula (I), and ethylhexyl 2-cyano-3,3-diphenylacrylate. The present invention is a sunscreen cosmetic comprising hexyl diethylaminohydroxybenzoylbenzoate and a benzotriazole derivative represented by the following general formula (I). (In this formula, R' = a straight chain alkyl group of C1-C6 and R" = a straight chain alkyl group of C1-C3.) The object of the present invention is to provide a sunscreen cosmetic that prevents staining due to secondary adhesion to clothing.

  本发明是一种防晒化妆品，包括4-(1,1-二甲基乙基)-4'-甲氧基二苯甲酮甲烷，由以下通用式(I)表示的苯并三唑衍生物，以及乙基己基2-氰基-3,3-二苯基丙烯酸酯。本发明是一种防晒化妆品，包括己基二乙氨基羟基苯甲酰苯甲酸酯和由以下通用式(I)表示的苯并三唑衍生物。（在该式中，R' = C1-C6的直链烷基，R" = C1-C3的直链烷基。）本发明的目的是提供一种防晒化妆品，可防止因次生粘附到衣物而导致的染色。
• SUNSCREEN PREPARATIONS
  申请人：Shiseido Company, Limited

  公开号：EP2027847A1

  公开（公告）日：2009-02-25

  The present invention is a sunscreen cosmetic comprising a benzotriazole derivative represented by the following general formula (I) and metal oxide powder whose surface is treated with an alkylalkoxy silane. The present invention is a sunscreen cosmetic comprising an ultraviolet absorbent having absorption in the UV-A region and metal oxide powder whose surface is treated with an alkylalkoxy silane. The object of the present invention is to provide a sunscreen cosmetic that prevents staining due to secondary adhesion to clothing. General formula (I) (In this formula, R' = a straight chain alkyl group of C1-C6 and R" = a straight chain alkyl group of C1-C3.)

  本发明是一种防晒化妆品，包括以下一般式（I）所代表的苯并三唑衍生物和其表面经过烷基烷氧基硅烷处理的金属氧化物粉末。本发明是一种防晒化妆品，包括在紫外线A区域具有吸收作用的紫外线吸收剂和其表面经过烷基烷氧基硅烷处理的金属氧化物粉末。本发明的目的是提供一种防晒化妆品，可防止因次生粘附到衣物而导致的污渍。一般式（I）（在此式中，R' = C1-C6的直链烷基基团，R" = C1-C3的直链烷基基团。）
• SUNSCREEN COSMETIC COMPOSITION
  申请人：Shiseido Company, Limited

  公开号：EP1944012A1

  公开（公告）日：2008-07-16

  The present invention is a sunscreen cosmetic comprising 2,4-bis [[4-(2-ethylhexyloxy)-2-hydroxy] phenyl]-6-(4-methoxyphenyl)-1,3,5-triazine and a specific benzotriazole derivative. Also, the present invention is a sunscreen cosmetic comprising a specific benzotriazole derivative and a specific alkylaryl 1,3-propanedione silicone derivative. An object of the present invention is to provide a sunscreen cosmetic that exhibits superior UV-A absorption capacity and excellent stability and also sufficiently dissolves 2,4-bis [[4-(2-ethylhexyloxy)-2-hydroxy] phenyl]-6-(4-methoxyphenyl)-1,3,5-triazine, which has low solubility and crystallizes easily. Another object is to provide a sunscreen cosmetic that can synergistically improve the ultraviolet absorption capacity of conventional ultraviolet absorbents.

  本发明是一种防晒化妆品，包括2,4-双[[4-(2-乙基己氧基)-2-羟基]苯基]-6-(4-甲氧基苯基)-1,3,5-三嗪和一种特定的苯并三唑衍生物。此外，本发明是一种防晒化妆品，包括一种特定的苯并三唑衍生物和一种特定的烷基芳基1,3-丙二酮硅氧烷衍生物。本发明的目的是提供一种具有优越的UV-A吸收能力和优异稳定性的防晒化妆品，同时充分溶解2,4-双[[4-(2-乙基己氧基)-2-羟基]苯基]-6-(4-甲氧基苯基)-1,3,5-三嗪，该化合物溶解度低且容易结晶。另一个目的是提供一种可以协同改善传统紫外线吸收剂的紫外线吸收能力的防晒化妆品。