(bicyclo[2.2.1]hept-5-enyl)methyl monochloroacetate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: (bicyclo[2.2.1]hept-5-enyl)methyl monochloroacetate
• 英文别名: [(1S,2R,4S)-2-bicyclo[2.2.1]hept-5-enyl]methyl 2-chloroacetate
• 化学式: C₁₀H₁₃ClO₂
• 分子量: 200.665
• InChiKey: YEQPPBCBKNMCKW-YIZRAAEISA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  13
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.7
• 拓扑面积：
  26.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  氯乙酸丙烯酯 、 环戊二烯 在 对苯二酚 作用下， 反应 6.0h， 生成 (bicyclo[2.2.1]hept-5-enyl)methyl monochloroacetate 、 (bicyclo[2.2.1]hept-5-enyl)methyl monochloroacetate
  参考文献：
  名称：

  Synthesis of bicyclo[2.2.1]hept-5-enyl methyl esters of haloacetic acids

  摘要：

  Synthesis of norbornenyl methyl esters of a number of haloacetic acids via [4+2] cycloaddition of cyclopentadiene to allyl esters of these acids was examined. The yield and isomer composition of the synthesized compounds were examined in relation to the reaction conditions, and the best conditions for their preparation were found.

  DOI：

  10.1134/s1070427208100182

文献信息

• Synthesis of bicyclo[2.2.1]hept-5-enyl methyl esters of haloacetic acids
  作者：T. G. Kyazimova、E. G. Mamedbeili、A. V. Nagiev、E. I. Suleimanova、Kh. S. Khalilov

  DOI：10.1134/s1070427208100182

  日期：2008.10

  Synthesis of norbornenyl methyl esters of a number of haloacetic acids via [4+2] cycloaddition of cyclopentadiene to allyl esters of these acids was examined. The yield and isomer composition of the synthesized compounds were examined in relation to the reaction conditions, and the best conditions for their preparation were found.