N,N-diphenyl-oxalamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: N,N-diphenyl-oxalamide
• 英文别名: N,N-Diphenyl-oxalamid；Oxalsaeure-amid-diphenylamid；N.N-Diphenyl-oxamid；N,N-diphenyloxamide；N,N'-Diphenyl-oxamid；Diphenyloxamide；N',N'-diphenyloxamide
• 化学式: C₁₄H₁₂N₂O₂
• 分子量: 240.261
• InChiKey: RYKIMYINWPEUBW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  18
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  63.4
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  3-(N,N-diphenylamino)-3-oxopropanenitrile 在 permanganate(VII) ion 作用下， 生成 二苯基草酸 、 N,N-diphenyl-oxalamide
  参考文献：
  名称：

  Guareschi, Chemische Berichte, 26 Ref. <1893>,93

  摘要：

  DOI：

文献信息

• PROCESS FOR ALKENYLATING CARBOXAMIDES
  申请人：Staffel Wolfgang

  公开号：US20090131657A1

  公开（公告）日：2009-05-21

  The present invention relates to a process for preparing N-(1-alkenyl)carboxamides of the formula I, which comprises reacting a carboxamide of the formula II with an alkyne of the formula III in the presence of a catalyst selected from among carbonyl complexes, halides and oxides of rhenium, manganese, tungsten, molybdenum, chromium and iron.

  本发明涉及一种制备式I的N-(1-烯基)羧酰胺的方法，包括在选择自铼、锰、钨、钼、铬和铁的羰基配合物、卤化物和氧化物之一作为催化剂的情况下，将式II的羧酰胺与式III的炔烃反应。
• METHOD FOR CONVERTING HYDROXYL GROUP OF ALCOHOL
  申请人：Takasago International Corporation

  公开号：US20210047254A1

  公开（公告）日：2021-02-18

  The present invention relates to: a method for converting a hydroxyl group of an alcohol; and a catalyst which makes the method possible. A method for converting a hydroxyl group of an alcohol according to the present invention is characterized by producing a compound represented by CH(R 1 )(R 2 )Nu (wherein R 1 , R 2 and Nu are as defined below) by reacting an alcohol represented by CH(R 1 )(R 2 )OH (wherein each of R 1 and R 2 represents a hydrogen atom, an optionally substituted alkyl group, or the like) and a compound having an active proton, which is represented by H-Nu (wherein Nu represents a group represented by —CHX 1 -EWG 1 or —NR 3 R 4 ; X 1 represents a hydrogen atom or the like; EWG 1 represents an electron-withdrawing group; and each of R 3 and R 4 represents a hydrogen atom, an optionally substituted alkyl group, or the like), with each other in the presence of a complex of a group 7-11 metal of the periodic table and at least one solid base that is selected from the group consisting of layered double hydroxides, composite oxides and calcium hydroxide.

  本发明涉及：将醇的羟基转化为的方法；以及使该方法成为可能的催化剂。根据本发明的将醇的羟基转化为的方法的特征在于，在周期表的7-11族金属群的复合物存在下，通过将一个由CH(R1)(R2)OH（其中R1和R2分别表示氢原子、可选择取代的烷基基团或类似物）表示的醇与一个具有活性质子的化合物（其中Nu表示由—CHX1-EWG1或—NR3R4表示的基团；X1表示氢原子或类似物；EWG1表示电子吸引基团；R3和R4分别表示氢原子、可选择取代的烷基基团或类似物）反应，从而产生一个由CH(R1)(R2)Nu（其中R1、R2和Nu如下定义）表示的化合物。同时，所述反应中至少选择一种来自层状双氢氧化物、复合氧化物和氢氧化钙的固体碱作为催化剂。
• Method for the synthesis of amides and related products from esters or ester-like compounds
  申请人：Gojon-Zorrilla Gabriel

  公开号：US20050027120A1

  公开（公告）日：2005-02-03

  A versatile, eco-friendly, and efficient method for the convenient conversion of esters and ester-like compounds into amides, peptides, carbamates, ureas, oxamides, oxamates, hydrazides, oxazolidinones, pyrazolones, oxazolidinediones, barbituric acids, and other molecules containing one or more OCN moieties in the presence of a diol or polyol is disclosed.

  本发明公开了一种多功能、环保、高效的方法，用于在二醇或多元醇存在的情况下，将酯和类酯化合物方便地转化为酰胺、肽、氨基甲酸酯、脲、氧化酰胺、氧化酰酸酯、肼、噁唑烷酮、噁唑烷二酮、巴比妥酸和其他含有一个或多个OCN基团的分子。
• NOVEL SULFAMOYL-PHENYL-UREIDO COMPOUNDS AND THEIR USE AS MEDICAMENT
  申请人：PEGORARO Stefano

  公开号：US20100197640A1

  公开（公告）日：2010-08-05

  The present invention relates to novel sulfamoyl-phenyl-ureido compounds having the formula (I) or a physiologically acceptable salt or derivative thereof which are suitable for the therapy of infections caused by protozoa and in particular uncomplicated or severe malaria caused by plasmodia.

  本发明涉及具有化学式（I）的新型磺胺酰基苯基脲类化合物或其生理上可接受的盐或衍生物，适用于治疗由原虫引起的感染，特别是由疟原虫引起的非并发或严重疟疾。
• PROCESS FOR MANUFACTURE OF PENTAERYTHRITOL DIPHOSPHITES
  申请人：Larke W. Carroll

  公开号：US20050131244A1

  公开（公告）日：2005-06-16

  A method is disclosed for the production of pentaerythritol diphosphites of high spiro isomer content. The pentaerythritol diphosphites are produced via sequential transesterification of pentaerythritol with a monophosphite followed by a substituted phenol or other alcohol, wherein the transesterification reactions are carried out under controlled conditions of temperature and pressure. The unique reaction conditions result in intermediate and final pentaerythritol diphosphites of high spiro isomer content and high total yield of the diphosphites.

  本发明公开了一种生产高螺旋异构体含量的对叔丁基苯酚二磷酸酯的方法。该方法通过将对叔丁基苯酚或其他醇与单磷酸酯逐步进行酯交换反应，其中酯交换反应在控制温度和压力的条件下进行。独特的反应条件导致中间体和最终产物对叔丁基苯酚二磷酸酯具有高螺旋异构体含量和高总产率的特点。