2-(methylthio)hexafluoroisobutyryl chloride

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: 2-(methylthio)hexafluoroisobutyryl chloride
• 英文别名: 3,3,3-trifluoro-2-methylsulfanyl-2-(trifluoromethyl)propanoyl chloride
• 化学式: C₅H₃ClF₆OS
• 分子量: 260.588
• InChiKey: XUVFLVNRHYGZRT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  14
• 可旋转键数：
  2
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.8
• 拓扑面积：
  42.4
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  2-(methylthio)hexafluoroisobutyryl chloride 在 水 作用下， 以 二乙二醇二甲醚 为溶剂， 以72%的产率得到methyl 2H-hexafluoroisopropyl sulfide
  参考文献：
  名称：

  2-(Methylthio)pentafluoropropene

  摘要：

  2-(Methylthio) pentafluoropropene was obtained by dehydrofluorination of methyl 2H-hexafluoroisopropyl sulfide by the BF3.NEt(3) complex. Its reactivity with respect to allyl alcohol and hexamethyldisilazane was studied. The electrophilcity of 2-(methylthio)pentafluoropropene was compared with the properties of terminal polyfluoroalkenes whose behavior in these reactions has been studied previously.

  DOI：

  10.1007/bf00699139
• 作为产物：
  描述：

  氯硫基甲烷 、 3,3,3-三氟-2-(三氟甲基)丙-1-烯-1-酮 以82%的产率得到2-(methylthio)hexafluoroisobutyryl chloride
  参考文献：
  名称：

  2-(Methylthio)pentafluoropropene

  摘要：

  2-(Methylthio) pentafluoropropene was obtained by dehydrofluorination of methyl 2H-hexafluoroisopropyl sulfide by the BF3.NEt(3) complex. Its reactivity with respect to allyl alcohol and hexamethyldisilazane was studied. The electrophilcity of 2-(methylthio)pentafluoropropene was compared with the properties of terminal polyfluoroalkenes whose behavior in these reactions has been studied previously.

  DOI：

  10.1007/bf00699139

文献信息

• 2-(Methylthio)pentafluoropropene
  作者：V. G. Andreev、A. Yu. Sizov、A. F. Kolomiets

  DOI：10.1007/bf00699139

  日期：1994.1

  2-(Methylthio) pentafluoropropene was obtained by dehydrofluorination of methyl 2H-hexafluoroisopropyl sulfide by the BF3.NEt(3) complex. Its reactivity with respect to allyl alcohol and hexamethyldisilazane was studied. The electrophilcity of 2-(methylthio)pentafluoropropene was compared with the properties of terminal polyfluoroalkenes whose behavior in these reactions has been studied previously.