双[4-(2-羟基乙氧基)-3,5-二溴苯基]砜 | 53714-39-9

• 物质功能分类: 化学试剂 - 有机试剂 - 砜、亚砜类化合物
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 双[4-(2-羟基乙氧基)-3,5-二溴苯基]砜
• 中文别名: 双[3,5-二溴-4-(2-羟基乙氧基)苯基]砜；双[3,5-二溴-4-(2-羟乙氧基)苯基]砜；二[4-(2-羟基乙氧基)-3,5-二溴苯基]砜
• 英文名称: 2-[4-[4-(2-hydroxyethoxy)-3,5-dibromophenyl]sulfonyl-2,6-dibromophenoxy]ethanol
• 英文别名: 2,2'-(Sulphonylbis((2,6-dibromo-4,1-phenylene)oxy))bisethanol；2-[2,6-dibromo-4-[3,5-dibromo-4-(2-hydroxyethoxy)phenyl]sulfonylphenoxy]ethanol
• CAS: 53714-39-9
• 化学式: C₁₆H₁₄Br₄O₆S
• 分子量: 653.966
• InChiKey: OFBQIWFJRDGFEK-UHFFFAOYSA-N

物化性质

• 溶解度：
  溶于二甲基甲酰胺

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  27
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  101
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  二苯并噻吩-4-硼酸 、 双[4-(2-羟基乙氧基)-3,5-二溴苯基]砜 在 potassium phosphate 、 palladium diacetate 、 三(邻甲基苯基)磷 作用下， 以 水 为溶剂， 生成 2-[4-[4-(2-hydroxyethoxy)-3,5-di(dibenzo[b,d]thien-4-yl)phenyl]sulfonyl-2,6-(dibenzo[b,d]thien-4-yl)phenoxy]ethanol
  参考文献：
  名称：

  [EN] (HET)ARYL SUBSTITUTED BISPHENOL COMPOUNDS AND THERMOPLASTIC RESINS
  [FR] COMPOSÉS DE BISPHÉNOL SUBSTITUÉS PAR (HÉT)ARYLE ET RÉSINES THERMOPLASTIQUES

  摘要：

  The present invention relates to compounds of the formula (I) where X is selected from the group consisting of a single bond, O, N-(C1-C4)-alkyl, N-Ar1, CR5R6, S, S(O) and SO2; Z1and Z2are independently selected from hydrogen, -Alk-OH, -CH2-Ar2-CH2-OH, -Alk'-C(O)ORX, -CH2-Ar2-C(O)ORXand -C(O)-Ar2-C(O)ORx, where Rxis selected from the group consisting of hydrogen, phenyl, benzyl and C1-C4-alkyl; R1and R2are independently selected from the group consisting of optionally substituted mono- or polycyclic aryl having from 6 to 26 carbon atoms as ring members and optionally substituted mono- or polycyclic hetaryl having a total of 5 to 26 atoms as ring members, R5is selected from the group consisting of hydrogen, C1-C4-alkyl and a radical Ar1; R6is selected from the group consisting of hydrogen and C1-C4-alkyl; Alk is C2-C4-alkandiyl; provided that R1and R2are not both phenyl, if R3and R4are both hydrogen. The present invention also relates to use of the compounds of the formula (I) as defined herein as a monomer for producing thermoplastic resins comprising a structural unit represented by formulae (II) below where # represents a connection point to a neighboring structural unit; and where X, Z1a, Z2a, R1, R2, R3and R4are as defined herein, and to such thermoplastic resins. The present invention also relates optical devices made of a thermoplastic resin comprising a structural unit represented by formulae (II) as defined herein.

  公开号：

  WO2023038156A1

文献信息

• Method of producing hybridoma and utilization thereof
  申请人：Tomita Masahiro

  公开号：US20070026455A1

  公开（公告）日：2007-02-01

  The present invention provides a method of producing an antibody-producing hybridoma, which includes fusing a B cell immunized in vitro and a myeloma cell, and which is more efficient and practical than the conventional methods, more specifically a method of producing an antibody-producing hybridoma, which includes fusing a B cell immunized with an antigenic substance in the coexistence of a cytokine and a glycolipid in vitro, and a myeloma cell, and use thereof.

  本发明提供了一种生产抗体产生的杂交瘤的方法，包括将体外免疫的B细胞与骨髓瘤细胞融合，比传统方法更高效、更实用，更具体地说，本发明提供了一种在体外将免疫原物质免疫的B细胞在细胞因子和糖脂质共存的条件下与骨髓瘤细胞融合，以及其使用的方法。
• FIRE RETARDANT ORGANIC HIGH MOLECULAR COMPOSITION
  申请人：ACOME, SOCIETE COOPERATIVE DE TRAVAILLEURS

  公开号：EP0042440A1

  公开（公告）日：1981-12-30

  An organic high molecular composition having improved fire retardance, which is prepared by compounding a fire retardant composition comprising (a) organic high molecular material, (b) organic fire retardant, and (c) incombustible, polar, inorganic powder, with (d) a multi-functional compound and (e) an organic compound represented by the following formula [wherein Z represents an oxygen atom or a sulfur atom, A represents a divalent hydrocarbyl group containing 2 to 20 carbon atoms, optionally having a substituent, and forming a ring together with the adjacent two carbon atoms and B, and B represents an oxygen atom or an imino group represented by -NY- (wherein Y represents a hydrogen atom, a halogen atom or an organic group containing 30 or less carbon atoms)] or the hydrolyzate thereof.

  一种具有更佳阻燃性的有机高分子组合物，其制备方法是将包含(a)有机高分子材料、(b)有机阻燃剂和(c)不可燃极性无机粉末的阻燃组合物与(d)多功能化合物和(e)由下式表示的有机化合物复合在一起 [其中 Z 代表氧原子或硫原子，A 代表含有 2 至 20 个碳原子的二价烃基，可选择具有一 个取代基，并与相邻的两个碳原子和 B 一起形成一个环，B 代表氧原子或由 -NY- 代表的亚氨基（其中 Y 代表氢原子、卤素原子或含有 30 个或更少碳原子的有机基团））]或其水解物。
• A polyester composition used for thermoshrinkable films
  申请人：Toyo Boseki Kabushiki Kaisha

  公开号：EP0751183A2

  公开（公告）日：1997-01-02

  A polyester composition used for thermoshrinkable films, wherein the composition comprises acid components including terephthalic acid and glycol components including ethylene glycol, and wherein the composition has a transformation ratio of 0.175 or more, is described.

  本文描述了一种用于热收缩薄膜的聚酯组合物，其中该组合物包含包括对苯二甲酸在内的酸组分和包括乙二醇在内的乙二醇组分，并且该组合物的转化率为 0.175 或更高。
• MONOCLONAL ANTIBODY FOR IMMUNOLOGICALLY ANALYZING OR CONCENTRATING ENDOCRINE DISRUPTING SUBSTANCE OR ITS DEGRADATION PRODUCT AND UTILIZATION OF THE SAME
  申请人：Takeda Chemical Industries, Ltd.

  公开号：EP1057890A1

  公开（公告）日：2000-12-06

  A hybridoma which produces a monoclonal antibody against an endocrine disruptor or its degradation product obtained by fusing spleen cells or lymphoid cells of an animal having been immunized with a complex of the endocrine disruptor or a compound similar thereto with a protein with myeloma cells; the monoclonal antibody produced thereby; and a method for immunologically detecting the endocrine disruptor or its degradation product and a method for immunologically concentrating the same each by using the above antibody.

  一种杂交瘤，可产生针对内分泌干扰素或其降解产物的单克隆抗体，该抗体是通过将免疫过内分泌干扰素或类似化合物与蛋白质的复合物的动物脾细胞或淋巴细胞与骨髓瘤细胞融合而获得的；由此产生的单克隆抗体；以及利用上述抗体对内分泌干扰素或其降解产物进行免疫检测的方法和对内分泌干扰素或其降解产物进行免疫浓缩的方法。
• METHOD FOR IMMUNOLOGICALLY ANALYZING AND ASSAYING ENVIRONMENTAL POLLUTANT
  申请人：Takeda Chemical Industries, Ltd.

  公开号：EP1207393A1

  公开（公告）日：2002-05-22

  An environmental contaminant, its degradation product or a mixture thereof can be determined or analyzed in high sensitivity by immunoassay using a complex of an anti-immunoglobulin antibody supported on a carrier and a further antibody against the environmental contaminant or its degradation product bound to said anti-immunoglobulin antibody.

  环境污染物、其降解产物或其混合物可通过免疫测定法进行高灵敏度测定或分析，该方法使用的复合物包括支撑在载体上的抗免疫球蛋白抗体和与所述抗免疫球蛋白抗体结合的抗环境污染物或其降解产物的抗体。

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