N-[2-(5-methoxy-1-nitrosoindol-3-yl)ethyl]formamide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: N-[2-(5-methoxy-1-nitrosoindol-3-yl)ethyl]formamide
• 化学式: C₁₂H₁₃N₃O₃
• 分子量: 247.25
• InChiKey: LYXCSCHHGQDDPH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.4
• 重原子数：
  18
• 可旋转键数：
  4
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  72.7
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• [EN] MELATONIN DERIVATIVES AND THEIR USE FOR TREATING NEUROLOGICAL DYSFUNCTIONS<br/>[FR] DERIVES DE MELATONINE ET LEUR UTILISATION DANS LE TRAITEMENT DE DYSFONCTIONNEMENTS NEUROLOGIQUES
  申请人：FAUST PHARMACEUTICALS

  公开号：WO2004085395A1

  公开（公告）日：2004-10-07

  The present invention relates to compounds, of the general formula (I), wherein R1 represents -O-R7 in which R7 represents H, or a C1 to C4 alkyl group, R2 and R3, independently from one another, represent H, or a halogen atom, R4 represents H, methyl, or a halogen atom, Ra represents H, or a Cl to C4 alkyl group, Rb represents H, a CL to C4 alkyl group, or a C1 to C4 alkoxy group, for the manufacture of a drug for the treatment and/or prevention of diseases and conditions mediated by the imbalance of acetylcholine and NO, diseases and conditions mediated by the imbalance of acetylcholine and glutamate, or for improving memory capability.