2-Methylpropyl 4-cyano-3-hydroxybutanoate

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羟基酸及其衍生物
• 英文名称: 2-Methylpropyl 4-cyano-3-hydroxybutanoate
• 化学式: C₉H₁₅NO₃
• 分子量: 185.22
• InChiKey: HAPJMULFSUHAHA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.5
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  70.3
• 氢给体数：
  1
• 氢受体数：
  4

文献信息

• A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER
  申请人：Samsung Fine Chemicals Co., Ltd.

  公开号：EP1149068A1

  公开（公告）日：2001-10-31
• EP1149068A4
  申请人：——

  公开号：EP1149068A4

  公开（公告）日：2003-01-02
• US6586616B1
  申请人：——

  公开号：US6586616B1

  公开（公告）日：2003-07-01
• [EN] A PROCESS FOR PREPARING (R)-4-CYANO-3-HYDROXYBUTYRIC ACID ESTER<br/>[FR] PROCEDE DE PREPARATION DE DERIVES D'ESTER D'ACIDE (R)-4-CYANO-3-HYDROXYBUTYRIQUE
  申请人：SAMSUNG FINE CHEMICALS CO LTD

  公开号：WO2000046186A1

  公开（公告）日：2000-08-10

  The present invention relates to a process for preparing (R)-4-cyano-3-hydroxybutyric acid ester derivatives and more particularly, to a process for preparing optically pure (R)-4-cyano-3-hydroxybutyric acid ester derivatives expressed by formula (1) in high yield by performing cyanation and sequential esterification of (S)-3,4-epoxybutyric acid salt as a starting material. In said formula, R represents linear or branched alkyl group with 1∩5 carbon atoms or benzyl group.