[6-(Nitrooxymethyl)pyridin-2-yl]methyl 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: [6-(Nitrooxymethyl)pyridin-2-yl]methyl 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetate
• 化学式: C26H22ClN3O7
• 分子量: 523.9
• InChiKey: WOCWDBPSDOEKJO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.2
• 重原子数：
  37
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  126
• 氢给体数：
  0
• 氢受体数：
  8

文献信息

• NITROXYDERIVATIVES HAVING ANTIINFLAMMATORY, ANALGESIC AND ANTITHROMBOTIC ACTIVITY
  申请人：NicOx S.A.

  公开号：EP1154999B1

  公开（公告）日：2009-04-15
• US6613784B1
  申请人：——

  公开号：US6613784B1

  公开（公告）日：2003-09-02
• [EN] NITROXYDERIVATIVES HAVING ANTIINFLAMMATORY, ANALGESIC AND ANTITHROMBOTIC ACTIVITY<br/>[FR] DERIVES DE NITROXY PRESENTANT UNE ACTIVITE ANTI-INFLAMMATOIRE, ANALGESIQUE ET ANTI-THROMBOTIQUE
  申请人：NICOX SA

  公开号：WO2000051988A1

  公开（公告）日：2000-09-08

  Organic or inorganic salts of compounds of general formula: A - X1 - N(O)z for use as medicaments having anti-inflammatory, analgesic and antithrombotic activity, wherein A is R(COXu)t wherein t is 0 or 1; u is 0 or 1 and X is O, NH, NR1c wherein R1c us a C1-C10 alkyl and R is, for example, (Ia) wherein R1 is acetoxy, preferably in ortho position with respect to -CO- and R2 is hydrogen or acetylsalicylsalicylic acid derivatives; and X1 is the formula (B), Y being a ring containing at least one salified nitrogen atom.