(3S,5S)-5-Butyl-2,2,3-trimethyl-tetrahydro-furan

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 氧唑烯
• 英文名称: (3S,5S)-5-Butyl-2,2,3-trimethyl-tetrahydro-furan
• 英文别名: (3S,5S)-5-butyl-2,2,3-trimethyloxolane
• 化学式: C₁₁H₂₂O
• 分子量: 170.295
• InChiKey: ONYFLGWMJMUAIO-UWVGGRQHSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  12
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (3S,5R)-2,3-Dimethyl-2,5-nonanediol 在 吡啶 、 sodium hydroxide 作用下， 以 四氢呋喃 为溶剂， 生成 (3S,5S)-5-Butyl-2,2,3-trimethyl-tetrahydro-furan
  参考文献：
  名称：

  Electroorganic chemistry. 143. Electroreductively promoted diastereoselective coupling of ketones with allylic alcohols. Synthesis of optically active 1,4-diols

  摘要：

  Cathodic coupling of ketones with allylic alcohols has been found to take place with high regio- and stereoselectivities at the position gamma to the hydroxyl group to afford the corresponding 1,4-diols.

  DOI：

  10.1021/jo00081a001

文献信息

• Electroorganic chemistry. 143. Electroreductively promoted diastereoselective coupling of ketones with allylic alcohols. Synthesis of optically active 1,4-diols
  作者：Tatsuya Shono、Yoshiyuki Morishima、Naotake Moriyoshi、Manabu Ishifune、Shigenori Kashimura

  DOI：10.1021/jo00081a001

  日期：1994.1

  Cathodic coupling of ketones with allylic alcohols has been found to take place with high regio- and stereoselectivities at the position gamma to the hydroxyl group to afford the corresponding 1,4-diols.