(2S)-6-methyl-2-prop-2-enylheptan-1-ol

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: (2S)-6-methyl-2-prop-2-enylheptan-1-ol
• 化学式: C₁₁H₂₂O
• 分子量: 170.295
• InChiKey: QSPPHFOOGKDBET-LLVKDONJSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  12
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  (2S)-1-[(1S,5R,7R)-10,10-dimethyl-3,3-dioxo-3lambda6-thia-4-azatricyclo[5.2.1.01,5]decan-4-yl]-6-methyl-2-prop-2-enylheptan-1-one 在 lithium aluminium tetrahydride 作用下， 以 四氢呋喃 为溶剂， 反应 2.0h， 以92%的产率得到(2S)-6-methyl-2-prop-2-enylheptan-1-ol
  参考文献：
  名称：

  Polymerization and Telomerization of Chiral Acrylamides

  摘要：

  The acrylamide derived from Oppolzer's camphor sultam was polymerized and the resulting polymer was converted to poly(allyl acetate) through a reduction-acetylation sequence. The poly(allyl acetate) thus obtained was analyzed by NMR and was compared with authentically prepared isotactic as well as atactic poly(allyl acetate). The C-13 NMR peaks were assigned at the tetrad level. It is concluded that the poly(allyl acetate) obtained from poly(camphor sultam acrylamide) has an isotacticity level as low as 54%. Telomerization studies indicated that this chiral auxiliary is unable to control stereochemistry for telomers with two or more monomers incorporated. A model is proposed to account for the low selectivity in these polymerizations.

  DOI：

  10.1021/jo00085a017