5,6-bis[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]pyrazine-2,3-dicarbonitrile

• 分子结构分类: 有机化合物 - 有机硫化合物 - 硫醚类
• 英文名称: 5,6-bis[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]pyrazine-2,3-dicarbonitrile
• 化学式: C₁₂H₆N₈S₄
• 分子量: 390.497
• InChiKey: YJJKFQITKJFDEH-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  24
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  232
• 氢给体数：
  0
• 氢受体数：
  12

反应信息

• 作为产物：
  描述：

  1,4,5,6-四氢-5,6-二氧-2,3-吡嗪二甲腈 在 氯化亚砜 作用下， 以 吡啶 、 丙酮 为溶剂， 反应 4.5h， 生成 5,6-bis[(5-methyl-1,3,4-thiadiazol-2-yl)sulfanyl]pyrazine-2,3-dicarbonitrile
  参考文献：
  名称：

  Preparation of Magnesium Azaphthalocyanines by Cyclotetramerisation of S-Substituted 4,5-Disulfanylpyrazine-2,3-dicarbonitriles.

  摘要：

  Four novel S-substituted 4,5-disulfanylpyrazine-2,3-dicarbonitriles have been obtained in a multistep synthesis from diaminomaleonitrile. Two of these dicarbonitriles, with ethyl or benzyl S-substituents, give pure magnesium azaphthalocyanines in good yields when reacted with magnesium propoxide in propanol and dioxane. Aromatic S-substituents are less stable during the reaction conditions used for cyclisations, and product mixtures are obtained.

  DOI：

  10.3891/acta.chem.scand.50-1153

文献信息

• Preparation of Magnesium Azaphthalocyanines by Cyclotetramerisation of S-Substituted 4,5-Disulfanylpyrazine-2,3-dicarbonitriles.
  作者：Eva H. Mørkved、Lars T. Holmaas、Helge Kjøsen、Georg Hvistendahl、Markku Leskelä、Mika Polamo、Muhammed Nour Homsi、Frank K. H. Kuske、Monika Haugg、Nathalie Trabesinger-Rüf、Elmar G. Weinhold

  DOI：10.3891/acta.chem.scand.50-1153

  日期：——

  Four novel S-substituted 4,5-disulfanylpyrazine-2,3-dicarbonitriles have been obtained in a multistep synthesis from diaminomaleonitrile. Two of these dicarbonitriles, with ethyl or benzyl S-substituents, give pure magnesium azaphthalocyanines in good yields when reacted with magnesium propoxide in propanol and dioxane. Aromatic S-substituents are less stable during the reaction conditions used for cyclisations, and product mixtures are obtained.