(4-methoxyphenyl)-bisthienylmethane

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: (4-methoxyphenyl)-bisthienylmethane
• 英文别名: (4-methoxy-phenyl)-di-[2]thienyl-methane；(4-Methoxy-phenyl)-di-[2]thienyl-methan；2-[(4-Methoxyphenyl)-thiophen-2-ylmethyl]thiophene
• 化学式: C₁₆H₁₄OS₂
• 分子量: 286.419
• InChiKey: WKVUVITZNKHLES-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.7
• 重原子数：
  19
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  65.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  4,4'-二甲氧基苯酚酯 在 乙醚 、 碘 、 溶剂黄146 作用下， 生成 (4-methoxyphenyl)-bisthienylmethane
  参考文献：
  名称：

  The Pinacol Rearrangement in the Heterocyclic Series. III. Numerical Migratory Aptitudes

  摘要：

  DOI：

  10.1021/ja01639a035

文献信息

• Efficient synthesis of triarylmethanes via bisarylation of aryl aldehydes with arenes catalyzed by silica gel-supported sodium hydrogen sulfate
  作者：Yixin Leng、Fang Chen、Li Zuo、Wenhu Duan

  DOI：10.1016/j.tetlet.2010.02.157

  日期：2010.4

  An efficient synthesis of triarylmethanes has been developed via bisarylation of aryl aldehydes with arenes catalyzed by silica gel-supported sodium hydrogen sulfate in a solvent-free system. The new method features high yield, mild reaction conditions, and environmental friendliness.

  在无溶剂体系中，通过硅胶负载的硫酸氢钠催化芳基醛与芳烃的二芳基化，已开发出三芳基甲烷的有效合成方法。该新方法具有收率高，反应条件温和和环境友好的特点。
• Melamine Trisulfonic Acid: A New Efficient Catalyst for the Synthesis of Aryldithienylmethanes
  作者：Liqiang Wu、Yunhui Yan、Fulin Yan

  DOI：10.1080/10426507.2011.559496

  日期：2012.2.1

  Abstract An efficient method has been developed for the synthesis of dithienylmethanes via bisarylation of aldehydes with thiophene in the presence of melamine trisulfonic acid as a catalyst under solvent-free conditions. GRAPHICAL ABSTRACT

  摘要 开发了一种在无溶剂条件下，在三聚氰胺三磺酸作为催化剂的情况下，通过醛与噻吩的双芳基化合成二噻吩基甲烷的有效方法。图形概要
• Unique versatility of Amberlyst 15. An acid and solvent-free paradigm towards synthesis of bis(heterocyclyl)methane derivatives
  作者：Kamaljit Singh、Shivali Sharma、Amit Sharma

  DOI：10.1016/j.molcata.2011.07.007

  日期：2011.8

  Bis(heterocyclyl)methanes, key intermediates for a variety of chemical, biochemical and material science relevant targets, have been obtained in a synthetically useful manner using Amberlyst 15 ion-exchange resin. This method promises versatility, cost-effectiveness, and efficiency. (C) 2011 Elsevier B.V. All rights reserved.
• Wang, Yingling; Lu, Guangzhou; Wu, Liqiang, Asian Journal of Chemistry, 2011, vol. 23, # 9, p. 4221 - 4222
  作者：Wang, Yingling、Lu, Guangzhou、Wu, Liqiang

  DOI：——

  日期：——
• TRIARYLMETHYL RADICALS AND THE USE OF INERT CARBON FREE RADICALS IN MRI
  申请人：Nycomed Innovation AB

  公开号：EP0515458B1

  公开（公告）日：1995-08-23