反式-2-[3-(4-叔丁基苯基)-2-甲基-2-丙烯]丙二腈 | 300364-84-5

• 物质功能分类: 分析化学 - 标准品 - 光谱标准品
• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 反式-2-[3-(4-叔丁基苯基)-2-甲基-2-丙烯]丙二腈
• 中文别名: 反式-2-[3-(4-叔丁基苯基)-2-甲基-2-亚丙烯基]丙二腈；反-2-[3-(4-叔丁基苯基)-2-甲基-2-亚丙烯基]丙二腈
• 英文名称: trans-2-[3-(4-tert-Butylphenyl)-2-methyl-2-propenylidene]malononitrile
• 英文别名: 2-[(E)-3-(4-tert-butylphenyl)-2-methylprop-2-enylidene]propanedinitrile
• CAS: 300364-84-5
• 化学式: C₁₇H₁₈N₂
• 分子量: 250.34
• InChiKey: OIASAVWSBWJWBR-UKTHLTGXSA-N

物化性质

• 熔点：
  123-126 °C
• 沸点：
  392.5±37.0 °C(Predicted)
• 密度：
  1.029±0.06 g/cm3(Predicted)
• 溶解度：
  可溶于DMSO（少许）、甲醇（少许）

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  19
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  47.6
• 氢给体数：
  0
• 氢受体数：
  2

安全信息

• 危险等级：
  6.1
• 危险品标志：
  Xn
• 安全说明：
  S36
• 危险类别码：
  R20/21/22
• WGK Germany：
  3
• 海关编码：
  29269090,2926909090

文献信息

• [EN] (AZIRIDINYL HYDROXY)-FUNCTIONAL ORGANIC COMPOUNDS<br/>[FR] COMPOSÉS ORGANIQUES FONCTIONNELS D'(AZIRIDINYLE HYDROXY)
  申请人：COVESTRO NETHERLANDS BV

  公开号：WO2021148558A1

  公开（公告）日：2021-07-29

  The invention relates to particular (aziridinyl hydroxy)-functional organic component. The invention further relates to liquid compositions comprising said (aziridinyl hydroxy)-functional organic component. The invention further relates to coating compositions comprising said (aziridinyl hydroxy)-functional organic component. The invention further relates to liquid coating compositions comprising said (aziridinyl hydroxy)-functional organic component. The invention further relates to a kit-of-parts comprising in one of its parts a liquid composition comprising a particular (aziridinyl hydroxy)-functional organic component. The invention further relates to cured forms of said liquid compositions, coating compositions, and liquid coating compositions. The invention further relates to articles comprising the (aziridinyl hydroxy)-functional organic component and/or the liquid compositions and/or the liquid coating compositions and/or their cured forms. The invention further relates to various uses of the (aziridinyl hydroxy)- functional organic component and/or said liquid compositions, and/or said liquid coating compositions, and/or said kit-of-parts and/or said cured forms.

  该发明涉及特定的（环氧环丙基羟基）-功能有机组分。该发明还涉及包含所述（环氧环丙基羟基）-功能有机组分的液体组合物。该发明还涉及包含所述（环氧环丙基羟基）-功能有机组分的涂料组合物。该发明还涉及包含所述（环氧环丙基羟基）-功能有机组分的液体涂料组合物。该发明还涉及一种部件中包含液体组合物的套件，所述液体组合物包含特定的（环氧环丙基羟基）-功能有机组分。该发明还涉及所述液体组合物、涂料组合物和液体涂料组合物的固化形式。该发明还涉及包含（环氧环丙基羟基）-功能有机组分和/或液体组合物和/或液体涂料组合物和/或其固化形式的物品。该发明还涉及（环氧环丙基羟基）-功能有机组分和/或所述液体组合物和/或所述液体涂料组合物和/或所述套件和/或所述固化形式的各种用途。
• [EN] THIOL-PROTECTED AMINO ACID DERIVATIVES AND USES THEREOF<br/>[FR] DÉRIVÉS D'ACIDE AMINÉ À PROTECTION THIOL ET LEURS UTILISATIONS
  申请人：JOHANNES GUTENBERG UNIVERSITÄT MAINZ

  公开号：WO2015169908A1

  公开（公告）日：2015-11-12

  The present invention relates to thiol-protected amino acid derivatives of formulae (I) and (II), peptides and block-copolymers containing the compounds and methods for preparing same. The present invention also relates to core-shell particles comprising such thiol-protected block-copolymers and compositions thereof.

  本发明涉及式(I)和(II)的巯基保护氨基酸衍生物，含有这些化合物的肽和嵌段共聚物，以及制备它们的方法。本发明还涉及包含这种巯基保护嵌段共聚物的核-壳粒子及其组合物。
• MULTI-AZIRIDINE COMPOUND
  申请人：DSM IP ASSETS B.V.

  公开号：US20210332031A1

  公开（公告）日：2021-10-28

  The present invention relates to a multi-aziridine compound having: a) from 2 to 6 of the following structural units (A): (A) whereby R′, R″, R 1 , R 2 , R 3 and R 4 are as defined herein m is an integer from 1 to 6; b) one or more linking chains wherein each one of these linking chains links two of the structural units A; and c) a molecular weight in the range from 600 Daltons to 5000 Daltons. The multi-aziridine compound can be used for example for crosslinking of for example carboxylic acid functional polymers dissolved and/or dispersed in an aqueous medium.

  本发明涉及一种多环氮丙烷化合物，其具有：a) 2至6个以下结构单元（A）：（A），其中R′、R″、R1、R2、R3和R4如本文所定义，m为1至6的整数；b) 一个或多个连接链，其中每个连接链连接两个结构单元A；以及c) 分子量在600道尔顿至5000道尔顿范围内。该多环氮丙烷化合物可用于例如交联溶解和/或分散在水性介质中的羧酸官能聚合物。
• [EN] HYDROPHOBICALLY MODIFIED ANTISENSE OLIGONUCLEOTIDES COMPRISING A TRIPLE ALKYL CHAIN<br/>[FR] OLIGONUCLÉOTIDES ANTI-SENS MODIFIÉES PAR HYDROPHOBIE COMPRENANT UNE CHAÎNE ALKYLE TRIPLE
  申请人：INST NAT SANTE RECH MED

  公开号：WO2014195432A1

  公开（公告）日：2014-12-11

  The present invention concerns an oligonucleotide modified by substitution at the 3' or the 5' end by a moiety comprising at least three saturated or unsaturated, linear or branched hydrocarbon chains comprising from 2 to 30 carbon atoms, and the use therefore as a medicament, in particular for use for treating cancer.

  本发明涉及一种寡核苷酸，其在3'端或5'端被至少包含三条饱和或不饱和、线性或支链烃链的基团取代，并且作为药物的用途，特别用于治疗癌症。
• ANTIMICROBIAL COMPOUNDS AND NANOSTRUCTURES
  申请人：THE BOEING COMPANY

  公开号：US20180362462A1

  公开（公告）日：2018-12-20

  The present disclosure provides compounds and nanostructures having one or more quaternary ammonium salts, compositions including the compounds and nanostructures, and methods useful for treating conditions using the compounds, nanostructures, and compositions. In at least one aspect, a compound is represented by formula (I): or a pharmaceutically acceptable salt thereof, wherein: Q is fluoro, chloro, bromo, or iodo; each of s, b, and n is independently an integer from about 10 to about 100; and each of v, j, p, z, q, x and m is independently an integer from 1 to about 20.

  本公开提供具有一个或多个季铵盐的化合物和纳米结构，包括该化合物和纳米结构的组合物以及使用该化合物、纳米结构和组合物治疗疾病的有用方法。在至少一个方面，化合物由公式（I）表示：或其药学上可接受的盐，其中：Q为氟、氯、溴或碘；每个s、b和n独立地为约10至约100的整数；每个v、j、p、z、q、x和m独立地为1至约20的整数。