2-chloro-1,1-difluoropropene

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 乙烯基卤化物
• 英文名称: 2-chloro-1,1-difluoropropene
• 英文别名: chlorodifluoropropene；Chlorodifluoropropen；Chlorodifluoropropene；2-chloro-1,1-difluoroprop-1-ene
• 化学式: C₃H₃ClF₂
• 分子量: 112.507
• InChiKey: SBICOSJPCBAFED-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.9
• 重原子数：
  6
• 可旋转键数：
  0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  三氟氯丙烯 在 三乙基硅烷 、 aluminum(III) fluoride 作用下， 以 全氘代环己烷 为溶剂， 反应 168.0h， 生成 2-chloro-1,1-difluoropropene
  参考文献：
  名称：

  Selective dehydrofluorination of 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) to 2-chloro-3,3,3-trifluoropropene (HFO-1233xf) using nanoscopic aluminium fluoride catalysts at mild conditions

  摘要：

  Aluminium chlorofluoride (ACF, AlClxF3-x, x = 0.05-0.3) and high-surface aluminium fluoride (HS-AlF3) were tested as heterogeneous catalysts for the reactivity towards 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb), which is a potent greenhouse gas. Selective activation and dehydrofluorination of the C-F bond was observed, under remarkable conditions, such as mild temperatures (70 degrees C) and without the need for a hydrogen source as a driving force. Consecutive reactions were developed by using C6D6 as a solvent or adding Et3SiH. Thus, the production of the dehydrofluorination product 2-chloro-3,3,3-trifluoropropene (HFO-1233xf) can be coupled to a hydroarylation or hydrodefluorination reaction in one-pot procedures.

  DOI：

  10.1016/j.jfluchem.2019.04.001

文献信息

• Selective dehydrofluorination of 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb) to 2-chloro-3,3,3-trifluoropropene (HFO-1233xf) using nanoscopic aluminium fluoride catalysts at mild conditions
  作者：Maëva-Charlotte Kervarec、Clara Patricia Marshall、Thomas Braun、Erhard Kemnitz

  DOI：10.1016/j.jfluchem.2019.04.001

  日期：2019.5

  Aluminium chlorofluoride (ACF, AlClxF3-x, x = 0.05-0.3) and high-surface aluminium fluoride (HS-AlF3) were tested as heterogeneous catalysts for the reactivity towards 2-chloro-1,1,1,2-tetrafluoropropane (HCFC-244bb), which is a potent greenhouse gas. Selective activation and dehydrofluorination of the C-F bond was observed, under remarkable conditions, such as mild temperatures (70 degrees C) and without the need for a hydrogen source as a driving force. Consecutive reactions were developed by using C6D6 as a solvent or adding Et3SiH. Thus, the production of the dehydrofluorination product 2-chloro-3,3,3-trifluoropropene (HFO-1233xf) can be coupled to a hydroarylation or hydrodefluorination reaction in one-pot procedures.