| 1492905-43-7

• 分子结构分类: 有机化合物 - 生物碱及其衍生物 - 阿朴菲
• CAS: 1492905-43-7
• 化学式: C₆₅H₉NO₂
• 分子量: 835.792
• InChiKey: RTCCYZSDBHAZFU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  18.88
• 重原子数：
  68.0
• 可旋转键数：
  3.0
• 环数：
  31.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  31.23
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为产物：
  描述：

  氨基甲酸丁酯 、 足球烯 在 亚碘酰苯 、 碘 作用下， 以 氯苯 为溶剂， 反应 5.0h， 以15%的产率得到
  参考文献：
  名称：

  Hypervalent Iodine Reagent Mediated Reaction of [60]Fullerene with Amines

  摘要：

  The hypervalent iodine reagent mediated reaction of C-60 with various readily available amines for the easy preparation of iminofullerenes has been developed. The reaction between C-60 and sulfonamides can be effectively controlled to selectively synthesize azafulleroids or aziridinofullerenes under PhI(OAc)(2)/I-2 or PhIO/I-2/CuCl/lutidine conditions, respectively. For phosphamide and urea, only one isomer is obtained. However, carbamate gives three kinds of products. Interestingly, the reaction of C-60 with alkylamines allows the effective synthesis of aziridinofullerenes and regioselective cis-1-bisaziridinofullerenes.

  DOI：

  10.1021/jo402079m

文献信息

• Hypervalent Iodine Reagent Mediated Reaction of [60]Fullerene with Amines
  作者：Chun-Bao Miao、Xin-Wei Lu、Ping Wu、Jiaxing Li、Wen-Long Ren、Meng-Lei Xing、Xiao-Qiang Sun、Hai-Tao Yang

  DOI：10.1021/jo402079m

  日期：2013.12.6

  The hypervalent iodine reagent mediated reaction of C-60 with various readily available amines for the easy preparation of iminofullerenes has been developed. The reaction between C-60 and sulfonamides can be effectively controlled to selectively synthesize azafulleroids or aziridinofullerenes under PhI(OAc)(2)/I-2 or PhIO/I-2/CuCl/lutidine conditions, respectively. For phosphamide and urea, only one isomer is obtained. However, carbamate gives three kinds of products. Interestingly, the reaction of C-60 with alkylamines allows the effective synthesis of aziridinofullerenes and regioselective cis-1-bisaziridinofullerenes.