methyl (2S)-2-hydroxydocosanoate

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: methyl (2S)-2-hydroxydocosanoate
• 化学式: C₂₃H₄₆O₃
• 分子量: 370.616
• InChiKey: KUHHQOLYDNMSJW-QFIPXVFZSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  10
• 重原子数：
  26
• 可旋转键数：
  21
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.96
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  methyl (2S)-2-hydroxydocosanoate 、 乙酸酐 在 吡啶 作用下， 生成 methyl 2-acetoxydocosanoate
  参考文献：
  名称：

  New norterpenoids and a sphingolipid fromCarissa opaca

  摘要：

  Chemical investigations on the aerial parts of Carissa opaca resulted in the isolation and characterization of two new nor-triterpenoids (compounds 1 and 2) and a new sphingolipid (compound 3) together with six known compounds. The structures of all the isolates were established using spectral data. All the isolated compounds showed DPPH radical scavenging and enzyme inhibitory activities against enzymes acetylcholinesterase, butyrylcholinesterase, and lipoxygenase.

  DOI：

  10.1080/10286020.2015.1064904
• 作为产物：
  描述：

  甲醇 、 (2S,3S,4R,15E)-2-{[(2R)-2-hydroxydocosanoyl]amino}eicos-15-ene-1,3,4-triol 在 盐酸 作用下， 以 水 为溶剂， 反应 15.0h， 生成 methyl (2S)-2-hydroxydocosanoate
  参考文献：
  名称：

  New norterpenoids and a sphingolipid fromCarissa opaca

  摘要：

  Chemical investigations on the aerial parts of Carissa opaca resulted in the isolation and characterization of two new nor-triterpenoids (compounds 1 and 2) and a new sphingolipid (compound 3) together with six known compounds. The structures of all the isolates were established using spectral data. All the isolated compounds showed DPPH radical scavenging and enzyme inhibitory activities against enzymes acetylcholinesterase, butyrylcholinesterase, and lipoxygenase.

  DOI：

  10.1080/10286020.2015.1064904

文献信息

• New norterpenoids and a sphingolipid from<i>Carissa opaca</i>
  作者：Shehla Parveen、Muhammad Saleem、Naheed Riaz、Muhammad Ashraf、Qurat-ul-Ain、Muhammad Farrukh Nisar、Abdul Jabbar

  DOI：10.1080/10286020.2015.1064904

  日期：2016.3.3

  Chemical investigations on the aerial parts of Carissa opaca resulted in the isolation and characterization of two new nor-triterpenoids (compounds 1 and 2) and a new sphingolipid (compound 3) together with six known compounds. The structures of all the isolates were established using spectral data. All the isolated compounds showed DPPH radical scavenging and enzyme inhibitory activities against enzymes acetylcholinesterase, butyrylcholinesterase, and lipoxygenase.