1,3,6,8-tetrakis(4,5-dihydro-4-methyl-1H-imidazol-2-yl)pyrene

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 英文名称: 1,3,6,8-tetrakis(4,5-dihydro-4-methyl-1H-imidazol-2-yl)pyrene
• 英文别名: 5-methyl-2-[3,6,8-tris(5-methyl-4,5-dihydro-1H-imidazol-2-yl)pyren-1-yl]-4,5-dihydro-1H-imidazole
• 化学式: C₃₂H₃₄N₈
• 分子量: 530.676
• InChiKey: VICLPTXFKGAHDP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.6
• 重原子数：
  40
• 可旋转键数：
  4
• 环数：
  8.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  97.6
• 氢给体数：
  4
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  1,3,6,8-tetracyanopyrene 、 1,2-丙二胺 在 硫化氢 作用下， 以 乙醇 为溶剂， 反应 18.0h， 生成 1,3,6,8-tetrakis(4,5-dihydro-4-methyl-1H-imidazol-2-yl)pyrene
  参考文献：
  名称：

  A general synthesis of diaryl cyclic diamidines

  摘要：

  A convenient and general method has been developed for directly converting bis-nitriles to cyclic diamidines using reagents derived from diaminoalkanes saturated with hydrogen sulfide. A 1:1 mixture of a diaminoalkane and ethyl alcohol (or without) was effective in most cases (72-88%). The synthetic utility of this methodology in the preparation of 1,3,6,8-tetrakis(cyclic amidino)pyrenes from 1,3,6,8-tetracyanopyrene is described. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)00307-x

文献信息

• A general synthesis of diaryl cyclic diamidines
  作者：Jarosław Spychała

  DOI：10.1016/s0040-4039(99)00307-x

  日期：1999.4

  A convenient and general method has been developed for directly converting bis-nitriles to cyclic diamidines using reagents derived from diaminoalkanes saturated with hydrogen sulfide. A 1:1 mixture of a diaminoalkane and ethyl alcohol (or without) was effective in most cases (72-88%). The synthetic utility of this methodology in the preparation of 1,3,6,8-tetrakis(cyclic amidino)pyrenes from 1,3,6,8-tetracyanopyrene is described. (C) 1999 Elsevier Science Ltd. All rights reserved.