(2R,3R)-N-p-methoxyphenyl-2,3-dimethylsuccinimide

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯烷类
• 英文名称: (2R,3R)-N-p-methoxyphenyl-2,3-dimethylsuccinimide
• 英文别名: (3R,4R)-1-(4-methoxyphenyl)-3,4-dimethylpyrrolidine-2,5-dione
• 化学式: C₁₃H₁₅NO₃
• 分子量: 233.267
• InChiKey: JGLHMVJLAHUEOR-RKDXNWHRSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.8
• 重原子数：
  17
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.38
• 拓扑面积：
  46.6
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  2,3-二甲基马来酸酐 在 Marchantia polymorpha cells 、 MSK-II medium 作用下， 以 二甲基亚砜 为溶剂， 反应 120.0h， 生成 (2R,3R)-N-p-methoxyphenyl-2,3-dimethylsuccinimide
  参考文献：
  名称：

  Asymmetric hydrogenation of the C–C double bond of 1- and 1,2-methylated maleimides with cultured suspension cells of Marchantia polymorpha

  摘要：

  Suspension cultured cells of Marchantia polymorpha have the potential to hydrogenate the C-C double bonds of 2-methyl- and 2,3-dimethylmaleimide derivatives to give enantiomerically pure (2R)-2-methyl- and (2R, 3R)-2, 3-dimethylsuccinimide derivatives, respectively. (c) 2006 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetasy.2006.06.030

文献信息

• Asymmetric hydrogenation of the C–C double bond of 1- and 1,2-methylated maleimides with cultured suspension cells of Marchantia polymorpha
  作者：Mohamed-Elamir F. Hegazy、Kozo Shishido、Toshifumi Hirata

  DOI：10.1016/j.tetasy.2006.06.030

  日期：2006.7

  Suspension cultured cells of Marchantia polymorpha have the potential to hydrogenate the C-C double bonds of 2-methyl- and 2,3-dimethylmaleimide derivatives to give enantiomerically pure (2R)-2-methyl- and (2R, 3R)-2, 3-dimethylsuccinimide derivatives, respectively. (c) 2006 Elsevier Ltd. All rights reserved.