N,N-diisobutylmethanesulfonamide

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 有机磺酸及其衍生物
• 英文名称: N,N-diisobutylmethanesulfonamide
• 英文别名: N,N-bis(2-methylpropyl)methanesulfonamide
• 化学式: C₉H₂₁NO₂S
• mdl: MFCD04227569
• 分子量: 207.337
• InChiKey: QGBCJVDWVFQBDN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  13
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  1.0
• 拓扑面积：
  45.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  二异丁胺 、 二甲基亚砜 在 potassium iodide 作用下， 反应 8.0h， 以80%的产率得到N,N-diisobutylmethanesulfonamide
  参考文献：
  名称：

  Electrosynthesis of sulfonamides from DMSO and amines under mild conditions

  摘要：

  在室温下，以DMSO为溶剂，使用带有-SO₂Me基团的前体，开发了一种新的电化学氧化和胺化反应，用于合成磺酰胺。

  DOI：

  10.1039/d1cc00026h

文献信息

• SUBSTITUTED-QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND THE USES THEREOF
  申请人：Purdue Pharma L.P.

  公开号：US20150141643A1

  公开（公告）日：2015-05-21

  The invention relates to Substituted-Quinoxaline-Type Piperidine Compounds, compositions comprising an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Substituted-Quinoxaline-Type Piperidine Compound.

  该发明涉及取代喹喔啉型哌啶化合物，包括一种有效量的取代喹喔啉型哌啶化合物的组合物以及治疗或预防疾病的方法，例如疼痛，通过向需要治疗的动物施用一种有效量的取代喹喔啉型哌啶化合物。
• DYES FOR POLYMER COLORATION, THEIR PREPARATION AND THEIR USE
  申请人：Barbieru Roxana

  公开号：US20120174324A1

  公开（公告）日：2012-07-12

  The present invention relates to a dye of formula (I) where R 1 , R 2 , X, Y and t are each as defined in claim 1 , to its preparation and to its use.
• CYCLIC UREA- OR LACTAM-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF
  申请人：Shionogi & Co., Ltd.

  公开号：US20140045830A1

  公开（公告）日：2014-02-13

  The disclosure relates to Cyclic Urea- or Lactam-Substituted Quinoxaline-Type Piperidine Compounds of Formula (I): and pharmaceutically acceptable derivatives thereof wherein R 1 , R 2 , Q a , Y 1 , Z, A, B, Q x , E, G, J, M, U, W, and a are as defined herein, compositions comprising an effective amount of a Cyclic Urea- or Lactam-Substituted Quinoxaline-Type Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Cyclic Urea- or Lactam-Substituted Quinoxaline-Type Piperidine Compound.
• PHOSPHORUS-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF
  申请人：Tadesse Dawit

  公开号：US20140128346A1

  公开（公告）日：2014-05-08

  The disclosure relates to Phosphorus-Substituted Quinoxaline-Type Piperidine Compounds of Formula (I): and pharmaceutically acceptable derivatives thereof wherein the dashed line, A, B, Q, R 1 , R 2 , R 3 , R 4 , Y 1 , Z, and a are as defined herein, compositions comprising an effective amount of a Phosphorus-Substituted Quinoxaline-Type Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of a Phosphorus-Substituted Quinoxaline-Type Piperidine Compound.
• AZETIDINE-SUBSTITUTED QUINOXALINE-TYPE PIPERIDINE COMPOUNDS AND USES THEREOF
  申请人：Purdue Pharma L.P.

  公开号：US20150011529A1

  公开（公告）日：2015-01-08

  The disclosure relates to Azetidine-Substituted Quinoxaline-Type Piperidine Compounds of Formula (I): and pharmaceutically acceptable derivatives thereof wherein the R 1 , R 2 , R 3 , Q, Y 1 , Z, A, B, a, and b are as defined herein, compositions comprising an effective amount of an Azetidine-Substituted Quinoxaline-Type Piperidine Compound, and methods to treat or prevent a condition, such as pain, comprising administering to an animal in need thereof an effective amount of an Azetidine-Substituted Quinoxaline-Type Piperidine Compound.