N-(2,2-Dimethoxyethyl)maleamic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: N-(2,2-Dimethoxyethyl)maleamic acid
• 英文别名: (Z)-4-(2,2-dimethoxyethylamino)-4-oxobut-2-enoic acid
• 化学式: C₈H₁₃NO₅
• 分子量: 203.195
• InChiKey: VACQOXIVQVPQKN-ARJAWSKDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.8
• 重原子数：
  14
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  84.9
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  氨基乙醛缩二甲醇 以 二氯甲烷 为溶剂， 以75%的产率得到N-(2,2-Dimethoxyethyl)maleamic acid
  参考文献：
  名称：

  Self- and diol reactive formaldehyde-free crosslinking monomers and

  摘要：

  一个由以下公式表示的化合物：##STR1##其中R是具有功能性的C.sub.3-C.sub.24烯丙基不饱和有机基团，使氮原子电子亏损，烯丙基不饱和功能性可聚合，R.sup.1是氢或C.sub.1-C.sub.4烷基基团，或R和R.sup.1与氮原子一起可以形成具有使氮原子电子亏损的烯丙基不饱和功能性可聚合的5至7环成员环，R.sup.2和R.sup.3是氢，C.sub.1-C.sub.4烷基或酰基基团，或R.sup.2和R.sup.3一起是C.sub.1-C.sub.4烷基烷基，R.sup.4是氢或C.sub.1-C.sub.4烷基、酰基、酯、酰胺或酸基团，n是1到10的整数，当R是(meth)acryloyl时，R.sup.2和R.sup.3是甲基，R.sup.1和R.sup.4是氢时，n不是1。

  公开号：

  US04864055A1

文献信息

• Self- and hydroxyl reactive formaldehyde-free cyclic hemiamidal and
  申请人：Air Products and Chemicals, Inc.

  公开号：US04691026A1

  公开（公告）日：1987-09-01

  A compound represented by the following formula: ##STR1## wherein R is a C.sub.3 -C.sub.24 olefinically unsaturated organic radical having functionality which renders the nitrogen atom electron deficient, the olefinic unsaturation functionality being polymerizable, R.sup.1 is hydrogen or a C.sub.1 -C.sub.4 alkyl radical, or R and R.sup.1 together with the nitrogen atom can form an olefinically unsaturated 5 to 7-member ring which has functionality that renders the nitrogen atom electron deficient and the olefinic unsaturation functionality is polymerizable, R.sup.2 and R.sup.3 are hydrogen, a C.sub.1 -C.sub.4 alkyl or acyl radical, or R.sup.2 and R.sup.3 together are a C.sub.2 -C.sub.4 alkylene group, R.sup.4 is hydrogen or a C.sub.1 -C.sub.4 alkyl, acyl, ester, amide or acid group, and n is an integer from 1 to 10, provided n is not 1 when R is (meth)acryloyl, R.sup.2 and R.sup.3 are methyl and R.sup.1 and R.sup.4 are hydrogen. Under acidic conditions the above compounds having R.sup.1 =hydrogen afford cyclic hemiamidals and hemiamide ketals of the following formula ##STR2##

  一个由以下式表示的化合物：##STR1##其中R是具有使氮原子电子亏损的官能团的C.sub.3 -C.sub.24烯烃不饱和有机基团，烯烃不饱和官能团是可聚合的，R.sup.1是氢或C.sub.1 -C.sub.4烷基基团，或者R和R.sup.1与氮原子一起可以形成一个具有使氮原子电子亏损的烯烃不饱和官能团且可聚合的5至7元环，R.sup.2和R.sup.3是氢、C.sub.1 -C.sub.4烷基或酰基基团，或者R.sup.2和R.sup.3一起是C.sub.2 -C.sub.4烷基基团，R.sup.4是氢或C.sub.1 -C.sub.4烷基、酰基、酯、酰胺或酸基团，n是从1到10的整数，当R为(meth)acryloyl，R.sup.2和R.sup.3为甲基，R.sup.1和R.sup.4为氢时，提供n不为1。在酸性条件下，具有R.sup.1=氢的上述化合物产生以下式的环烯酰胺和烯酰胺醇醚：##STR2##
• Polymers of self- and hydroxyl reactive formaldehyde-free cyclic
  申请人：Air Products and Chemicals, Inc.

  公开号：US04663410A1

  公开（公告）日：1987-05-05

  A compound represented by the following formula: ##STR1## wherein R is a C.sub.3 -C.sub.24 olefinically unsaturated organic radical having functionality which renders the nitrogen atom electron deficient, the olefinic unsaturation functionality being polymerizable, R.sup.1 is hydrogen or a C.sub.1 -C.sub.4 alkyl radical, or R and R.sup.1 together with the nitrogen atom can form an olefinically unsaturated 5 to 7-member ring which has functionality that renders the nitrogen atom electron deficient and the olefinic unsaturation functionality is polymerizable, R.sup.2 and R.sup.3 are hydrogen, a C.sub.1 -C.sub.4 alkyl or acyl radical, or R.sup.2 and R.sup.3 together are a C.sub.2 -C.sub.4 alkylene group, R.sup.4 is hydrogen or a C.sub.1 -C.sub.4 alkyl, acyl, ester, amide or acid group, and n is an integer from 1 to 10, provided n is not 1 when R is (meth)acryloyl, R.sup.2 and R.sup.3 are methyl and R.sup.1 and R.sup.4 are hydrogen. Under acidic conditions the above compounds in which R.sup.1 is hydrogen afford cyclic hemiamidals and hemiamide ketals of the following formula: ##STR2## The dialkyl acetal and ketal compounds and the cyclic hemiamidal and hemiamide ketal compounds can be homopolymerized or polymerized with other copolymerizable monomers.

  以下化合物的化学式：##STR1## 其中R是具有使氮原子电子不足的官能团的C.sub.3-C.sub.24烯烃不饱和有机基团，烯烃不饱和官能团是可聚合的，R.sup.1是氢或C.sub.1-C.sub.4烷基基团，或R和R.sup.1与氮原子一起可以形成具有使氮原子电子不足的烯烃不饱和5至7成员环，烯烃不饱和官能团是可聚合的，R.sup.2和R.sup.3是氢、C.sub.1-C.sub.4烷基或酰基基团，或R.sup.2和R.sup.3一起是C.sub.2-C.sub.4烷基撑链，R.sup.4是氢或C.sub.1-C.sub.4烷基、酰基、酯、酰胺或酸基团，n是1至10的整数，当R为(meth)acryloyl时，n不为1，R.sup.2和R.sup.3为甲基，R.sup.1和R.sup.4为氢。在酸性条件下，其中R.sup.1为氢的上述化合物会生成以下的环状半酰胺和半酰胺缩酮：##STR2## 双烷基缩醛和缩酮化合物以及环状半酰胺和半酰胺缩酮化合物可以与其他共聚单体进行均聚或共聚。
• Polymers of self- and diol reactive formaldehyde-free crosslinking
  申请人：Air Products and Chemicals, Inc.

  公开号：US05463007A1

  公开（公告）日：1995-10-31

  A compound represented by the following formula: ##STR1## wherein R is a C.sub.3 -C.sub.24 olefinically unsaturated organic radical having functionality which renders the nitrogen atom electron deficient, the olefinic unsaturation functionality being polymerizable, R.sup.1 is hydrogen or a C.sub.1 -C.sub.4 alkyl radical, or R and R.sup.1 together with the nitrogen atom can form an olefinically unsaturated 5 to 7-member ring which has functionality that renders the nitrogen atom electron deficient and the olefinic unsaturation functionality is polymerizable, R.sup.2 and R.sup.3 are hydrogen, a C.sub.1 -C.sub.4 alkyl or acyl radical, or R.sup.2 and R.sup.3 together are a C.sub.2 -C.sub.4 alkylene group, R.sup.4 is hydrogen or a C.sub.1 -C.sub.4 alkyl, acyl, ester, amide or acid group, and n is an integer from 1 to 10, provided n is not 1 when R is (meth)acryloyl, R.sup.2 and R.sup.3 are methyl and R.sup.1 and R.sup.4 are hydrogen. Under acidic conditions the above compounds in which R.sup.1 is hydrogen afford cyclic hemiamidals and hemiamide ketals of the following formula: ##STR2## The dialkyl acetal and ketal compounds and the cyclic hemiamidal and hemiamide ketal compounds can be homopolymerized or polymerized with other copolymerizable monomers.

  以下化合物的化学式：##STR1## 其中，R是具有使氮原子电子不足的官能团的C.sub.3-C.sub.24烯丙基不饱和有机基，烯丙基不饱和官能团可聚合，R.sup.1是氢或C.sub.1-C.sub.4烷基基团，或R和R.sup.1与氮原子一起可以形成具有使氮原子电子不足的烯丙基不饱和5至7元环，烯丙基不饱和官能团可聚合，R.sup.2和R.sup.3是氢，C.sub.1-C.sub.4烷基或酰基基团，或R.sup.2和R.sup.3一起是C.sub.2-C.sub.4烷基基团，R.sup.4是氢或C.sub.1-C.sub.4烷基、酰基、酯基、酰胺基或酸基团，n是1至10的整数，当R为(meth)acryloyl，R.sup.2和R.sup.3为甲基，R.sup.1和R.sup.4为氢时，n不为1。在酸性条件下，其中R.sup.1为氢的上述化合物会生成以下的环状半酰胺和半酰胺醚：##STR2## 二烷基缩醛和缩酮化合物以及环状半酰胺和半酰胺醚化合物可以与其他共聚单体一起进行均聚或共聚。
• Self-and Hydroxyl reactive formaldehyde-free cyclic hemiamidal and
  申请人：Air Products and Chemicals, Inc.

  公开号：US04788288A1

  公开（公告）日：1988-11-29

  A compound represented by the following formula: ##STR1## wherein R is a C.sub.3 -C.sub.24 olefinically unsaturated organic radical having functionality which renders the nitrogen atom electron deficient, the olefinic unsaturation functionality being polymerizable, R.sup.1 is hydrogen or a C.sub.1 -C.sub.4 alkyl radical, or R and R.sup.1 together with the nitrogen atom can form an olefinically unsaturated 5 to 7-member ring which has functionality that renders the nitrogen atom electron deficient and the olefinic unsaturation functionality is polymerizable, R.sup.2 and R.sup.3 are hydrogen, a C.sub.1 -C.sub.4 alkyl or acyl radical, or R.sup.2 and R.sup.3 together are a C.sub.2 -C.sub.4 alkylene group, R.sup.4 is hydrogen or a C.sub.1 -C.sub.4 alkyl, acyl, ester, amide or acid group, and n is an integer from 1 to 10, provided n is not 1 when R is (meth)acryloyl, R.sup.2 and R.sup.3 are methyl and R.sup.1 and R.sup.4 are hydrogen. Under acidic conditions the above compounds having R.sup.1 =hydrogen afford cyclic hemiamidals and hemiamide ketals of the following formula ##STR2##

  以下化合物的化学式：##STR1## 其中R是具有使氮原子电子不足的官能团的C.sub.3-C.sub.24烯丙基不饱和有机基，烯丙基不饱和官能团可聚合，R.sup.1是氢或C.sub.1-C.sub.4烷基基团，或R和R.sup.1与氮原子一起可以形成具有使氮原子电子不足的烯丙基不饱和5至7环成员环，烯丙基不饱和官能团可聚合，R.sup.2和R.sup.3是氢，C.sub.1-C.sub.4烷基或酰基基团，或R.sup.2和R.sup.3一起是C.sub.2-C.sub.4烷基基团，R.sup.4是氢或C.sub.1-C.sub.4烷基，酰基，酯，酰胺或酸基团，n是1至10的整数，当R为（甲基）丙烯酰基，R.sup.2和R.sup.3为甲基，R.sup.1和R.sup.4为氢时，n不为1。在酸性条件下，具有R.sup.1 =氢的上述化合物会产生如下化合物的环状半胺和半胺酮：##STR2##
• Self- and diol reactive formaldehyde-free crosslinking monomers and their derived polymers
  申请人：AIR PRODUCTS AND CHEMICALS, INC.

  公开号：EP0201693A2

  公开（公告）日：1986-11-20

  A compound represented by the following formula:- wherein R is a C3-C24 olefinically unsaturated organic radical having functionality which renders the nitrogen atom electron deficient, the olefinic unsaturation functionality being polymerizable, R' is hydrogen or a C1-C4 alkyl radical, or R and R1 together with the nitrogen atom can form an olefinically unsaturated 5 to 7-member ring which has functionality that renders the nitrogen atom electron deficient and the olefinic unsaturation functionality is polymerizable, R2 and R3 are hydrogen, a C1-C4 alkyl or acyl radical, or R2 and R3 together are a C2-C4 alkylene group, R4 is hydrogen or a C1-C4 alkyl, acyl, ester, amide or acid group, and n is an integer from 1 to 10, provided n is not 1 when R is (meth)acryloyl, R2 and R3 are methyl and R' and R4 are hydrogen.

  下式所代表的化合物 其中 R 是 C3-C24 烯烃不饱和有机基，具有使氮原子缺电子的官能团，烯烃不饱和官能团可聚合、 R' 是氢或 C1-C4 烷基，或 R 和 R1 与氮原子一起可形成烯烃不饱和 5 至 7 元环，该环具有使氮原子缺电子的官能度，且烯烃不饱和官能度可聚合、 R2 和 R3 是氢、C1-C4 烷基或酰基，或 R2 和 R3 合在一起是一个 C2-C4 烯基、 R4 是氢或 C1-C4 烷基、酰基、酯基、酰胺基或酸基，以及 n 是 1 到 10 的整数，但当 R 是（甲基）丙烯酰基、R2 和 R3 是甲基、R'和 R4 是氢时，n 不是 1。