1-[bis(2-phenylethyl)phosphoroselenoyl]-3-(trimethylsilyl)prop-2-yn-1-ol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-[bis(2-phenylethyl)phosphoroselenoyl]-3-(trimethylsilyl)prop-2-yn-1-ol
• 英文别名: 1-[Bis(2-phenylethyl)phosphinoselenoyl]-3-trimethylsilylprop-2-yn-1-ol
• 化学式: C₂₂H₂₉OPSeSi
• 分子量: 447.491
• InChiKey: QRONGYVOIICZAP-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.77
• 重原子数：
  26
• 可旋转键数：
  8
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  20.2
• 氢给体数：
  1
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  bis(2-phenylethyl)phosphine selenide 、 3-三甲基甲硅烷基丙炔醛 以 四氢呋喃 为溶剂， 反应 5.0h， 以86%的产率得到1-[bis(2-phenylethyl)phosphoroselenoyl]-3-(trimethylsilyl)prop-2-yn-1-ol
  参考文献：
  名称：

  Non-Catalyzed, Atom-Economic, High-Yield Synthesis of Tertiary α-Hydroxyphosphane Selenides

  摘要：

  First examples of a Facile hydroselenophosphorylation of aldehydes are reported. Nucleophilic addition of P,Se-ambident secondary phosphane selenides to a series of aldehydes proceeds under catalyst-free conditions at room temperature to give tertiary alpha-hydroxyphosphane selenides in high yield.

  DOI：

  10.1055/s-2006-950340

文献信息

• Non-Catalyzed, Atom-Economic, High-Yield Synthesis of Tertiary α-Hydroxyphosphane Selenides
  作者：Boris Trofimov、Nina Gusarova、Nina Ivanova、Nataliya Konovalova、Boris Sukhov、Ludmila Baikalova、Lidiya Sinegovskaya、Dmitriy Pavlov

  DOI：10.1055/s-2006-950340

  日期：——

  First examples of a Facile hydroselenophosphorylation of aldehydes are reported. Nucleophilic addition of P,Se-ambident secondary phosphane selenides to a series of aldehydes proceeds under catalyst-free conditions at room temperature to give tertiary alpha-hydroxyphosphane selenides in high yield.