[bis(2-phenylethyl)phosphoroselenoyl](1-vinyl-1H-benzimidazol-2-yl)methanol

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 苯并咪唑类
• 英文名称: [bis(2-phenylethyl)phosphoroselenoyl](1-vinyl-1H-benzimidazol-2-yl)methanol
• 英文别名: [(1-Ethenylbenzimidazol-2-yl)-hydroxymethyl]-bis(2-phenylethyl)-selenidophosphanium；[(1-ethenylbenzimidazol-2-yl)-hydroxymethyl]-bis(2-phenylethyl)-selenidophosphanium
• 化学式: C₂₆H₂₇N₂OPSe
• 分子量: 493.447
• InChiKey: DWUUCPTYWNJXLI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.71
• 重原子数：
  31
• 可旋转键数：
  9
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.19
• 拓扑面积：
  38
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  bis(2-phenylethyl)phosphine selenide 、 1-乙烯基-1H-苯并咪唑-2-甲醛 以 四氢呋喃 为溶剂， 反应 5.0h， 以81%的产率得到[bis(2-phenylethyl)phosphoroselenoyl](1-vinyl-1H-benzimidazol-2-yl)methanol
  参考文献：
  名称：

  Non-Catalyzed, Atom-Economic, High-Yield Synthesis of Tertiary α-Hydroxyphosphane Selenides

  摘要：

  First examples of a Facile hydroselenophosphorylation of aldehydes are reported. Nucleophilic addition of P,Se-ambident secondary phosphane selenides to a series of aldehydes proceeds under catalyst-free conditions at room temperature to give tertiary alpha-hydroxyphosphane selenides in high yield.

  DOI：

  10.1055/s-2006-950340

文献信息

• Non-Catalyzed, Atom-Economic, High-Yield Synthesis of Tertiary α-Hydroxyphosphane Selenides
  作者：Boris Trofimov、Nina Gusarova、Nina Ivanova、Nataliya Konovalova、Boris Sukhov、Ludmila Baikalova、Lidiya Sinegovskaya、Dmitriy Pavlov

  DOI：10.1055/s-2006-950340

  日期：——

  First examples of a Facile hydroselenophosphorylation of aldehydes are reported. Nucleophilic addition of P,Se-ambident secondary phosphane selenides to a series of aldehydes proceeds under catalyst-free conditions at room temperature to give tertiary alpha-hydroxyphosphane selenides in high yield.