N-(4-vinylphenyl)picolinamide

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: N-(4-vinylphenyl)picolinamide
• 英文别名: N-(4-ethenylphenyl)pyridine-2-carboxamide
• 化学式: C₁₄H₁₂N₂O
• 分子量: 224.262
• InChiKey: LGDFWLPESGYRJG-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  17
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  42
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  吗啉 、 N-(4-vinylphenyl)picolinamide 在 四丁基碘化铵 、 三甲基乙酸钾 、 copper(II) bis(trifluoromethanesulfonate) 作用下， 以 乙腈 为溶剂， 反应 24.0h， 以69%的产率得到N-(2-morpholino-4-vinylphenyl)picolinamide
  参考文献：
  名称：

  芳烃与仲胺的铜催化电化学 C-H 胺化

  摘要：

  电化学氧化是对需要腐蚀性化学计量化学氧化剂的传统方法的一种环保解决方案。然而，迄今为止，结合过渡金属催化和电化学技术的 CH 官能化主要限于使用贵金属和分离的电池。在此，我们报告了使用未分割的电化学电池在室温下铜催化芳烃电化学 CH 胺化的第一个例子，从而为芳胺的构建提供了实用的解决方案。使用 n-Bu4NI 作为氧化还原介质对于这种转变至关重要。基于包括动力学曲线、同位素效应、循环伏安分析和自由基抑制实验在内的机理研究，该反应似乎是通过单电子转移 (SET) 过程进行的，并且可能涉及高价 Cu(III) 物质。这些发现为使用氧化还原介质的过渡金属催化电化学 CH 官能化反应提供了新途径。

  DOI：

  10.1021/jacs.8b07380
• 作为产物：
  描述：

  2-吡啶甲酸 在 草酰氯 、 三乙胺 、 N,N-二甲基甲酰胺 作用下， 以 二氯甲烷 为溶剂， 生成 N-(4-vinylphenyl)picolinamide
  参考文献：
  名称：

  芳烃与仲胺的铜催化电化学 C-H 胺化

  摘要：

  电化学氧化是对需要腐蚀性化学计量化学氧化剂的传统方法的一种环保解决方案。然而，迄今为止，结合过渡金属催化和电化学技术的 CH 官能化主要限于使用贵金属和分离的电池。在此，我们报告了使用未分割的电化学电池在室温下铜催化芳烃电化学 CH 胺化的第一个例子，从而为芳胺的构建提供了实用的解决方案。使用 n-Bu4NI 作为氧化还原介质对于这种转变至关重要。基于包括动力学曲线、同位素效应、循环伏安分析和自由基抑制实验在内的机理研究，该反应似乎是通过单电子转移 (SET) 过程进行的，并且可能涉及高价 Cu(III) 物质。这些发现为使用氧化还原介质的过渡金属催化电化学 CH 官能化反应提供了新途径。

  DOI：

  10.1021/jacs.8b07380

文献信息

• A flexible approach to Pd-catalyzed carbonylations via aroyl dimethylaminopyridinium salts
  作者：Jeffrey S. Quesnel、Alexander Fabrikant、Bruce A. Arndtsen

  DOI：10.1039/c5sc02949j

  日期：——

  The palladium catalyzed carbonylation of aryl halides in the presence of DMAP can allow the generation of highly electrophilic aroylating agents: aroyl–DMAP salts.

  帕拉铂催化的芳基卤化物羰基化反应在DMAP存在下可以生成高度亲电性的芳酰化试剂：芳酰-DMAP盐。
• Reactive oxygen detecting and/or absorbing compound, method for preparing said compound and a device comprising it
  申请人：Lapinte Claude

  公开号：US20070152186A1

  公开（公告）日：2007-07-05

  The inventive reactive oxygen detecting and/or absorbing compound is characterised in that it consists of a complex molecular metallic ( 1 )/ligand ( 2 ) derivatives which changes the colour thereof according to the oxydation degree of a metal and is connected to the surface of a solid support ( 3 ) by a covalent bond.
• ORGANIC PIEZOELECTRIC MATERIAL, ULTRASONIC OSCILLATOR USING THE SAME, METHOD FOR PRODUCING THE ULTRASONIC OSCILLATOR, ULTRASONIC PROBE AND ULTRASONIC MEDICAL DIAGNOSTIC IMAGING DEVICE
  申请人：Morita Kiyokazu

  公开号：US20110004102A1

  公开（公告）日：2011-01-06

  Disclosed is an organic piezoelectric material which has particularly excellent heat resistance, while exhibiting excellent transparency, surface gloss, adhesion and piezoelectric characteristics. Also disclosed are an ultrasonic oscillator used in an ultrasonic medical diagnostic imaging device, which is capable of highly sensitively receiving a high frequency wave and suitable for harmonic imaging technique, a method for producing the ultrasonic oscillator, an ultrasonic probe, and an ultrasonic medical diagnostic imaging device. The organic piezoelectric material is characterized in that the piezoelectric material is formed by laminating two or more films at the same time by a coating process.
• ORGANIC PIEZOELECTRIC MATERIAL, ULTRASONIC OSCILLATOR USING THE MATERIAL, METHOD FOR MANUFACTURING THE ULTRASONIC OSCILLATOR, ULTRASONIC PROBE, AND ULTRASONIC MEDICAL DIAGNOSTIC IMAGING DEVICE
  申请人：Morita Kiyokazu

  公开号：US20110021916A1

  公开（公告）日：2011-01-27

  Provided is an organic piezoelectric material which has excellent piezoelectric property, heat resistance property in particular. An ultrasonic oscillator, which is to be used for an ultrasonic medical diagnostic imaging device which can receive high frequencies at high sensitivity and is suitable for harmonic imaging techniques, a method for manufacturing such oscillator, and an ultrasonic probe are also provided. The ultrasonic medical diagnostic imaging device is provided by sing such oscillator, method and probe. The organic piezoelectric material is characterized by containing empty particles having an average particle diameter of 10 μm or less.
• ORGANIC PIEZOELECTRIC MATERIAL FILM, METHOD FOR PRODUCTION OF ORGANIC PIEZOELECTRIC MATERIAL FILM, METHOD FOR PRODUCTION OF ULTRASONIC OSCILLATOR, AND ULTRASONIC MEDICAL IMAGING INSTRUMENT
  申请人：Morita Kiyokazu

  公开号：US20110021918A1

  公开（公告）日：2011-01-27

  Disclosed is an organic piezoelectric material film which has little contaminants and has excellent piezoelectric properties. The organic piezoelectric material film is produced by casting a solution of an organic piezoelectric material in an organic solvent and subsequently drying the resulting product. The organic piezoelectric material film has a moisture content of 0.1 mass % or less.