7-(Chloroacetyl)indole, 97%

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吲哚及其衍生物
• 英文名称: 7-(Chloroacetyl)indole, 97%
• 英文别名: 2-chloro-1-(1H-indol-7-yl)ethanone
• 化学式: C₁₀H₈ClNO
• 分子量: 193.63
• InChiKey: XECUBKDUDDTVMX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  32.9
• 氢给体数：
  1
• 氢受体数：
  1

文献信息

• Compounds for Use in the Treatment of Bacterial Infections
  申请人：Universität Konstanz

  公开号：US20210393586A1

  公开（公告）日：2021-12-23

  The present invention relates to a compound which can be used in the treatment of infections with pathogenic bacteria, in particular pathogens mediating pathogenicity by quinolone dependent production of virulence factors, such as e.g. Pseudomonas aeruginosa and species of the genus Burkholderia , and which can be used for treating bacterial or chronic infections or can be used in combination with other anti-bacterial agents, such as antibiotics, to increase sensitivity of the bacteria for treatment of e.g. multiresistant strains in e.g. mammals.