3,5-dimethyl-1H-pyrrole-2,4-dicarboxylic acid, 4-ethyl 2-(2-pyridinylmethyl)ester

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡咯
• 英文名称: 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylic acid, 4-ethyl 2-(2-pyridinylmethyl)ester
• 英文别名: 4-ethyl 2-pyridin-2-ylmethyl 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate；4-O-ethyl 2-O-(pyridin-2-ylmethyl) 3,5-dimethyl-1H-pyrrole-2,4-dicarboxylate
• 化学式: C₁₆H₁₈N₂O₄
• mdl: MFCD08526939
• 分子量: 302.33
• InChiKey: SBTXERZLOHULQK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.312
• 拓扑面积：
  81.3
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  2-吡啶甲醇 在 三氟乙酸酐 作用下， 以 甲苯 为溶剂， 以77%的产率得到3,5-dimethyl-1H-pyrrole-2,4-dicarboxylic acid, 4-ethyl 2-(2-pyridinylmethyl)ester
  参考文献：
  名称：

  1H-pyrrole-2,4-dicarbonyl-derivatives and their use as flavoring agents

  摘要：

  本发明主要涉及式(I)的1H-吡咯-2,4-二羰基衍生物，其中R1、R2、R3、Z、Z'和J按描述定义，及其混合物，以及用作调味剂的使用。根据本发明的化合物适用于生产、赋予或增强鲜味。本发明进一步涉及包含式(I)化合物或式(I)化合物混合物的有效量的调味混合物、口腔消费的组成物以及即食、即用和半成品，以及用于生产、赋予、改变和/或增强特定风味印象的特定方法。

  公开号：

  EP2832233A1

文献信息

• 1H-PYRROLE-DICARBONYL-DERIVATIVES AND THEIR USE AS FLAVORING AGENTS
  申请人：IMAX DISCOVERY GMBH

  公开号：US20160198747A1

  公开（公告）日：2016-07-14

  The present invention primarily relates to 1H-pyrrole-2,4-dicarbonyl- derivatives of Formula (I) wherein R 1 , R 2 , R 3 , Z. Z′ and J are as defined in the description, to mixtures thereof and to the use thereof as flavoring agents. The compounds in accordance with the present invention are suitable for producing, imparting, or intensifying an umami flavor. The invention further relates to flavoring mixtures, compositions for oral consumption as well as ready-to-eat, ready-to-use and semifinished products, comprising an effective amount of the compound of Formula (I) or of a mixture of compounds of Formula (I) and to specific methods for producing, imparting, modifying and/or intensifying specific flavor impressions.
• [EN] 1H-PYRROLE-2,4-DICARBONYL-DERIVATIVES AND THEIR USE AS FLAVORING AGENTS<br/>[FR] DÉRIVÉS DE 1H-PYRROLE-2,4-DICARBONYLE, ET LEUR UTILISATION COMME AROMATISANTS
  申请人：IMAX DISCOVERY GMBH

  公开号：WO2015014609A1

  公开（公告）日：2015-02-05

  The present invention primarily relates to lH-pyrrole-2,4-dicarbonyl- derivatives of Formula (I) wherein R1, R2, R3, Z. Z' and J are as defined in the description, to mixtures thereof and to the use thereof as flavoring agents. The compounds in accordance with the present invention are suitable for producing, imparting, or intensifying an umami flavor. The invention further relates to flavoring mixtures, compositions for oral consumption as well as ready-to-eat, ready-to-use and semifinished products, comprising an effective amount of the compound of Formula (I) or of a mixture of compounds of Formula (I) and to specific methods for producing, imparting, modifying and/or intensifying specific flavor impressions.
• 1H-pyrrole-2,4-dicarbonyl-derivatives and their use as flavoring agents
  申请人：IMAX Discovery GmbH

  公开号：EP2832233A1

  公开（公告）日：2015-02-04

  The present invention primarily relates to 1H-pyrrole-2,4-dicarbonyl-derivatives of Formula (I) wherein R1, R2, R3, Z. Z' and J are as defined in the description, to mixtures thereof and to the use thereof as flavoring agents. The compounds in accordance with the present invention are suitable for producing, imparting, or intensifying an umami flavor. The invention further relates to flavoring mixtures, compositions for oral consumption as well as ready-to-eat, ready-to-use and semifinished products, comprising an effective amount of the compound of Formula (I) or of a mixture of compounds of Formula (I) and to specific methods for producing, imparting, modifying and/or intensifying specific flavor impressions.

  本发明主要涉及式(I)的1H-吡咯-2,4-二羰基衍生物，其中R1、R2、R3、Z、Z'和J按描述定义，及其混合物，以及用作调味剂的使用。根据本发明的化合物适用于生产、赋予或增强鲜味。本发明进一步涉及包含式(I)化合物或式(I)化合物混合物的有效量的调味混合物、口腔消费的组成物以及即食、即用和半成品，以及用于生产、赋予、改变和/或增强特定风味印象的特定方法。