6-(2,2,6,6-tetramethylpiperidin-1-oxyl-4-ylamino)-6-oxohexane-1-sulfonic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 6-(2,2,6,6-tetramethylpiperidin-1-oxyl-4-ylamino)-6-oxohexane-1-sulfonic acid
• 化学式: C₁₅H₂₉N₂O₅S
• 分子量: 349.472
• InChiKey: SEYNYSUMJBMDGI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -1.5
• 重原子数：
  23
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.93
• 拓扑面积：
  96.1
• 氢给体数：
  2
• 氢受体数：
  5

反应信息

• 作为产物：
  描述：

  4-(6-bromohexanoylamino)-2,2,6,6-tetramethylpiperidine-N-oxyl 在 sodium sulfite 作用下， 以 乙醇 为溶剂， 反应 3.0h， 以52%的产率得到6-(2,2,6,6-tetramethylpiperidin-1-oxyl-4-ylamino)-6-oxohexane-1-sulfonic acid
  参考文献：
  名称：

  Anionic WS-TEMPO-mediatory electrooxidation of alcohols in water: halide-free oxidation directed towards a totally closed system

  摘要：

  Electrooxidation of alcohols in water with water-soluble N-oxyl derivatives bearing a sulfonic acid group (anionic WS-TEMPOs) as a mediator proceeded to afford the corresponding ketones and aldehydes in moderate to good yields. The aqueous solution containing WS-TEMPOs could be readily recovered and reused for the electrooxidation of alcohols, thereby providing a totally closed system. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2007.10.088

文献信息

• Anionic WS-TEMPO-mediatory electrooxidation of alcohols in water: halide-free oxidation directed towards a totally closed system
  作者：Koichi Mitsudo、Hiroki Kumagai、Fumiko Takabatake、Jun Kubota、Hideo Tanaka

  DOI：10.1016/j.tetlet.2007.10.088

  日期：2007.12

  Electrooxidation of alcohols in water with water-soluble N-oxyl derivatives bearing a sulfonic acid group (anionic WS-TEMPOs) as a mediator proceeded to afford the corresponding ketones and aldehydes in moderate to good yields. The aqueous solution containing WS-TEMPOs could be readily recovered and reused for the electrooxidation of alcohols, thereby providing a totally closed system. (c) 2007 Elsevier Ltd. All rights reserved.