2-Pentyl-nitrobenzol

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Pentyl-nitrobenzol
• 英文别名: o-Pentylnitrobenzene；1-nitro-2-pentylbenzene
• 化学式: C₁₁H₁₅NO₂
• 分子量: 193.246
• InChiKey: GSNYOSHZJIDORJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.45
• 拓扑面积：
  45.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  戊基苯 在 硝酸 、 乙酸酐 作用下， 生成 2-Pentyl-nitrobenzol
  参考文献：
  名称：

  Amoretti; Mossini, Farmaco, Edizione Scientifica, 1967, vol. 22, # 10, p. 796 - 800

  摘要：

  DOI：

文献信息

• Inhibitors of DNA Methyltransferase
  申请人：Wahhab Amal

  公开号：US20080132525A1

  公开（公告）日：2008-06-05

  The invention relates to the inhibition of DNA methyltransferase isoforms DNMT1 and DNMT3b2. The invention provides compounds and methods for inhibiting DNMT1 and DNMT3b2.

  这项发明涉及抑制DNA甲基转移酶亚型DNMT1和DNMT3b2。该发明提供了用于抑制DNMT1和DNMT3b2的化合物和方法。
• 1-Aryl-2-N-, S- or O-substituted benzimidazole derivatives, their use for the production of pharmaceutical agents as well as pharmaceutical preparations that contain these derivatives
  申请人：——

  公开号：US20030125550A1

  公开（公告）日：2003-07-03

  The invention relates to novel benzimidazole derivatives with general formula I, whereby radicals R 1 , R 2 , R 3 , A, B, Y and Z have the meanings that are indicated in the description and the claims, the use of these compounds for the production of a pharmaceutical agent for treatment and prevention of diseases associated with microglia activation as well as pharmaceutical preparations that contain these compounds. 1

  该发明涉及具有一般式I的新型苯并咪唑衍生物，其中基团R1、R2、R3、A、B、Y和Z的含义如描述和索赔中所示，这些化合物用于生产用于治疗和预防与微胶质细胞激活相关疾病的药物剂，以及含有这些化合物的药物制剂。
• 1-Phenyl-2-heteroaryl-substituted benzimdazole derivatives, their use for the production of pharmaceutical agents as well as pharmaceutical preparations that contain these derivatives
  申请人：Schering Aktiengesellschaft

  公开号：US20030229085A1

  公开（公告）日：2003-12-11

  New benzimidazole derivatives are described, their production and their use for the production of pharmaceutical agents for treatment and prevention of diseases that are associated with a microglia activation and T-cell-mediated immunological diseases, as well as pharmaceutical preparations that contain the new benzimidazole derivatives.

  本文介绍了新的苯并咪唑衍生物，它们的制备方法以及它们用于生产用于治疗和预防与微神经胶质细胞活化和T细胞介导的免疫性疾病相关的药物，以及含有新的苯并咪唑衍生物的制药制剂。
• 1-alkyl-2-aryl-benzimidazole derivatives, their use for the production of pharmaceutial agents as well as pharmaceutical preparations that contain these derivatives
  申请人：Schering AG

  公开号：US20030055057A1

  公开（公告）日：2003-03-20

  The invention relates to novel benzimidazole derivatives with general formula I, whereby radicals R 1 , R 2 , R 3 , A, B and Y have the meanings that are indicated in the description and the claims, the use of these compounds for the production of a pharmaceutical agent for treating and for preventing diseases that are associated with microglia activation, as well as pharmaceutical preparations that contain these compounds. 1

  该发明涉及一种具有一般式I的新型苯并咪唑衍生物，其中基团R1、R2、R3、A、B和Y具有说明书和权利要求所示的含义，这些化合物的用途是生产用于治疗和预防与微胶质细胞活化相关的疾病的药物剂，以及含有这些化合物的制药制剂。
• 1-Phenyl-2-heteroaryl-substituted benzimidazole derivatives, their use for the production of pharmaceutical agents as well as pharmaceutical preparations that contain these derivatives
  申请人：Blume Thorsten

  公开号：US20050267160A1

  公开（公告）日：2005-12-01

  New benzimidazole derivatives are described, their production and their use for the production of pharmaceutical agents for treatment and prevention of diseases that are associated with a microglia activation and T-cell-mediated immunological diseases, as well as pharmaceutical preparations that contain the new benzimidazole derivatives.

  本文描述了新的苯并咪唑衍生物，它们的生产以及它们用于制备与微胶质细胞激活和T细胞介导的免疫性疾病有关的药物治疗和预防疾病的用途，以及包含新的苯并咪唑衍生物的制药制剂。