2,3,4-trimethoxy-aniline; hydrochloride

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: 2,3,4-trimethoxy-aniline; hydrochloride
• 英文别名: 2,3,4-Trimethoxy-anilin; Hydrochlorid；2,3,4-Trimethoxyaniline hydrochloride；2,3,4-trimethoxyaniline;hydrochloride
• 化学式: C₉H₁₃NO₃*ClH
• mdl: MFCD16990643
• 分子量: 219.668
• InChiKey: KPEUVSVPSFSOLU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.67
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.333
• 拓扑面积：
  53.7
• 氢给体数：
  2
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  2,3,4-trimethoxy-aniline; hydrochloride 、 硫酸二甲酯 、 对苯醌 生成 2,3,4,2',5'-Pentamethoxybiphenyl
  参考文献：
  名称：

  Stjernstroem,N.E.; Tengedal,J.E., Acta Chemica Scandinavica (1947), 1970, vol. 24, p. 338 - 340

  摘要：

  DOI：

文献信息

• NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USES, AND PROCESSES FOR PREPARING THEM
  申请人：Agouron Pharmaceuticals, Inc.

  公开号：EP1401427A2

  公开（公告）日：2004-03-31
• EP1401427A4
  申请人：——

  公开号：EP1401427A4

  公开（公告）日：2004-12-01
• [EN] NON-PEPTIDE GNRH AGENTS, PHARMACEUTICAL COMPOSITIONS AND METHODS FOR THEIR USE, AND PROCESSES FOR PREPARING THEM AND THEIR INTERMEDIATES<br/>[FR] AGENTS GNRH NON PEPTIDIQUES, COMPOSITIONS PHARMACEUTIQUES ET METHODES D'UTILISATION DE CES DERNIERES, PROCEDES DE PREPARATION DE CES COMPOSES ET DE LEURS INTERMEDIAIRES
  申请人：AGOURON PHARMA

  公开号：WO2002098363A2

  公开（公告）日：2002-12-12

  Non-peptide GnRH agents capable of inhibiting the effect of gonadotropin-releasing hormone are described. Such compounds and their pharmaceutically acceptable salts, prodrugs, and active metabolites are suitable for treating mammalian reproductive disorders and steroid hormone-dependent tumors as well as for regulating fertility, where suppression of gonadotropin release is indicated. Methods for synthesizing the compounds and intermediates useful in their preparation are also described.
• Stjernstroem,N.E.; Tengedal,J.E., Acta Chemica Scandinavica (1947), 1970, vol. 24, p. 338 - 340
  作者：Stjernstroem,N.E.、Tengedal,J.E.

  DOI：——

  日期：——