2-methyl-N-(4-(((2-methylpropyl)imino)methyl)phenyl)methylidene-1-propanamine

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-methyl-N-(4-(((2-methylpropyl)imino)methyl)phenyl)methylidene-1-propanamine
• 英文别名: N-(2-methylpropyl)-1-[4-(2-methylpropyliminomethyl)phenyl]methanimine
• 化学式: C₁₆H₂₄N₂
• 分子量: 244.38
• InChiKey: HVWITPUIBLGIPD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  18
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  24.7
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2-methyl-N-(4-(((2-methylpropyl)imino)methyl)phenyl)methylidene-1-propanamine 在 sodium tetrahydroborate 作用下， 以 甲醇 为溶剂， 反应 0.33h， 生成 N-(4-((isobutylamine)methyl)benzyl)-2-methyl-1-propanamine
  参考文献：
  名称：

  In Situ Oxidation−Imine Formation−Reduction Routes from Alcohols to Amines

  摘要：

  [GRAPHICS]Manganese dioxide is employed as an in situ oxidant for the one pot conversion of alcohols into imines, In combination with polymer-supported cyanoborohydride (PSCBH), a one-pot oxidation-imine formation-reduction sequence is reported, This procedure enables alcohols to be converted directly into both secondary and tertiary amines.

  DOI：

  10.1021/ol015819b
• 作为产物：
  描述：

  对苯二甲醇 、 异丁胺 在 manganese(IV) oxide 作用下， 以 二氯甲烷 为溶剂， 以91%的产率得到2-methyl-N-(4-(((2-methylpropyl)imino)methyl)phenyl)methylidene-1-propanamine
  参考文献：
  名称：

  In Situ Oxidation−Imine Formation−Reduction Routes from Alcohols to Amines

  摘要：

  [GRAPHICS]Manganese dioxide is employed as an in situ oxidant for the one pot conversion of alcohols into imines, In combination with polymer-supported cyanoborohydride (PSCBH), a one-pot oxidation-imine formation-reduction sequence is reported, This procedure enables alcohols to be converted directly into both secondary and tertiary amines.

  DOI：

  10.1021/ol015819b

文献信息

• In Situ Oxidation−Imine Formation−Reduction Routes from Alcohols to Amines
  作者：Leonie Blackburn、Richard J. K. Taylor

  DOI：10.1021/ol015819b

  日期：2001.5.1

  [GRAPHICS]Manganese dioxide is employed as an in situ oxidant for the one pot conversion of alcohols into imines, In combination with polymer-supported cyanoborohydride (PSCBH), a one-pot oxidation-imine formation-reduction sequence is reported, This procedure enables alcohols to be converted directly into both secondary and tertiary amines.