2,2'-bipyridyl-6-acid chloride

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2,2'-bipyridyl-6-acid chloride
• 英文别名: 2,2′-bipyridine-6-carbonyl chloride；2,2'-Bipyridine-6-carbonyl chloride；6-pyridin-2-ylpyridine-2-carbonyl chloride
• 化学式: C₁₁H₇ClN₂O
• 分子量: 218.642
• InChiKey: XKPXGIIAZLITJX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.3
• 重原子数：
  15
• 可旋转键数：
  2
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  42.8
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2,2'-bipyridyl-6-acid chloride 在 氯化亚砜 、 三乙胺 作用下， 以 二氯甲烷 为溶剂， 反应 32.0h， 生成 (S)-6-(4-(tert-butyl)-1-(p-tolyl)-4,5-dihydro-1H-imidazol-2-yl)-2,2'-bipyridine
  参考文献：
  名称：

  α-Alkylation of Nitriles with Alcohols Catalyzed by NNN′ Pincer Ru(II) Complexes Bearing Bipyridyl Imidazoline Ligands

  摘要：

  DOI：

  10.1021/acs.organomet.9b00146
• 作为产物：
  描述：

  6-氰基-2,2'-联吡啶 在 氯化亚砜 、 水 、 sodium hydroxide 作用下， 以 乙醇 为溶剂， 反应 1.0h， 生成 2,2'-bipyridyl-6-acid chloride
  参考文献：
  名称：

  α-Alkylation of Nitriles with Alcohols Catalyzed by NNN′ Pincer Ru(II) Complexes Bearing Bipyridyl Imidazoline Ligands

  摘要：

  DOI：

  10.1021/acs.organomet.9b00146

文献信息

• Transport of Potassium Picrate through a Liquid Membrane by Metal-Responsive Carriers
  作者：Shinji Tsuchiya、Manabu Seno

  DOI：10.1021/j100057a023

  日期：1994.2

  Metal-responsive carriers having three receptors, and conformational variations were synthesized. The transport experiments of potassium picrate using these carriers were performed, and the mechanism was analyzed by numerical simulations. It was found that the rates and the mechanisms of transport of potassium picrate facilitated by these new carriers depend on the conformation of the carriers. That is, the transport rate of potassium picrate by carrier I was fast and potassium picrate was transported easily against its concentration gradient. On the other hand, when carrier I was coordinated by cupric ion, carrier III of cis conformation was formed and the transport rate by this carrier III was slower. The efficient uphill transport of potassium picrate by carrier I arises both from the different extraction equilibrium constants between the aqueous phase containing potassium chloride and the aqueous phase without potassium chloride, and the weak interaction between potassium picrate and carrier I in the organic phase. The numerical simulation of this uphill transport has been performed by using a diffusion-limited process, and the calculated result is consistent with the experimental result. It was also found that the transport rate of potassium picrate depends on the substituents of the nitrogen atoms of diazacrown ether, which affects the interaction between diazacrown ether and potassium picrate.
• α-Alkylation of Nitriles with Alcohols Catalyzed by NNN′ Pincer Ru(II) Complexes Bearing Bipyridyl Imidazoline Ligands
  作者：Zhi-Hui Zhu、Yigao Li、Yan-Bing Wang、Zhi-Gang Lan、Xinju Zhu、Xin-Qi Hao、Mao-Ping Song

  DOI：10.1021/acs.organomet.9b00146

  日期：2019.5.13